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Acta ophthalmologica Scandinavica. Supplement最新文献

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On the structural origin of refractive instability and corneal haze after excimer laser keratectomy for myopia. 准分子激光角膜切除术后屈光不稳及角膜混浊的结构成因。
Torben Møller-Pedersen
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引用次数: 0
Epidemiology of retinitis pigmentosa in Denmark. 丹麦色素性视网膜炎的流行病学。
Pub Date : 2002-02-12 DOI: 10.1046/J.1395-3907.2002.00001.X
M. Haim
A nation-wide registration of Danish cases of retinitis pigmentosa (RP) provided 1890 persons diagnosed during the period 1850-1989. Prevalent at 1 January 1988 were 1301 persons (1:3943) comprising a multitude of different RP-types. Age specific prevalence rates demonstrated increasing rates of RP during the first four decades of life and a rather stable prevalence over the next 20-30 years. Corrected for incompleteness, a late decrease was found, reflecting an incomplete ascertainment of the oldest patients. A moving average method indicated an even later steady state value for the age-specific prevalence. The Danish prevalence figures were standardized according to the WHO World Standardized Prevalence Rates and compared with large studies from the USA and UK. No statistically significant difference was found. Usher syndrome was present in 12% of all RP-cases and Bardet-Biedl syndrome comprised 5%. Mental retardation was found in 144 cases (11%), mostly characterized by atypical RP. Nineteen per cent of patients affected by nonsystemic RP had an onset later than 30 years of age, whereas only a few per cent of persons with systemic RP had an RP onset after age 30 years. The Mendelian inheritance type of all cases was evaluated according to an unambiguous genetic classification, finding a larger amount of X-linked RP compared with other studies. Among nonsystemic RP-cases, 14.3% were found to be inherited as an X-linked trait whereas only 8.4% were autosomal dominantly inherited. The largest fraction was, as in previous materials, the simplex group (isolated cases) comprising 42.9% of the nonsystemic RP patients. Some factors influencing the results are discussed, with special emphasis on the problems associated with precise definitions of the Mendelian inheritance groups. A diagram according to the author's definition was constructed as a guideline ready for clinical application.
在全国范围内登记的丹麦色素性视网膜炎(RP)病例提供了1890人在1850-1989年期间诊断。1988年1月1日共有1301人(1:3943),包括多种不同类型的rp。按年龄划分的患病率显示,在生命的头40年里,RP的发病率呈上升趋势,而在接下来的20-30年里,RP的发病率相当稳定。纠正了不完整,发现了较晚的下降,反映了对老年患者的不完全确定。移动平均方法表明,特定年龄患病率的稳定状态值甚至更晚。丹麦的患病率数据根据世界卫生组织世界标准化患病率进行了标准化,并与美国和英国的大型研究进行了比较。差异无统计学意义。在所有rp病例中,Usher综合征占12%,Bardet-Biedl综合征占5%。144例(11%)出现智力迟钝,主要表现为非典型RP。19%的非全身性RP患者在30岁以后发病,而只有少数全身性RP患者在30岁以后发病。所有病例的孟德尔遗传类型根据明确的遗传分类进行评估,与其他研究相比,发现更多的x连锁RP。在非全身性rp病例中,14.3%被发现遗传为x连锁性状,而只有8.4%是常染色体显性遗传。如前所述,单纯性组(孤立病例)占非全身性RP患者的42.9%,占比最大。讨论了影响结果的一些因素,特别强调了与孟德尔遗传群的精确定义有关的问题。根据作者的定义构建了一个图表,作为临床应用的指导。
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引用次数: 253
Ocular fluorophotometry in human subjects and in swine - with particular reference to long-term pharmacokinetics. 人类受试者和猪的眼荧光光度法。特别参考长期药代动力学。
Lars Loumann Knudsen
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引用次数: 0
Normal tension glaucoma. 正常张力性青光眼。
M Roy Wilson, M S Creighton
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引用次数: 0
The Italian Association for the Study of Glaucoma 14th annual meeting. Rapallo, Italy, 11-13 March 1999. Abstracts. 意大利青光眼研究协会第14届年会。1999年3月11日至13日,意大利拉帕洛。摘要。
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引用次数: 0
Challenges, strategies and tools to optimize the management of ocular allergy. Proceedings of the 1st International Symposium. Monte Carlo, Monaco, June 22-25, 1998. 优化眼过敏管理的挑战、策略和工具。第一届国际学术研讨会论文集。1998年6月22日至25日,摩纳哥蒙特卡洛。
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引用次数: 0
Proceedings of the 13th Annual General Meeting of the Italian Association for the Study of Glaucoma. Rapallo, Italy, 13-14 March 1998. 意大利青光眼研究协会第13届年会论文集。意大利拉帕洛,1998年3月13日至14日。
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引用次数: 0
On the biomechanical properties of the cornea with particular reference to refractive surgery. 角膜的生物力学特性,特别是屈光手术。
J O Hjortdal
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引用次数: 0
Laurence-Moon-Bardet-Biedl syndrome. Clinical, electrophysiological and genetic aspects. Laurence-Moon-Bardet-Biedl综合症。临床,电生理和遗传方面。
R Riise
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引用次数: 0
Prepared association of metipranolol 0.1% + pilocarpine 2% and of timolol 0.5% + pilocarpine 2%. Comparison of clinical efficacy and topical tolerability in the treatment of patients affected by POAG tonometrically uncontrolled with beta-blocker alone (two-centre study). 制备了0.1%美安洛尔+ 2%匹罗卡平和0.5%替莫洛尔+ 2%匹罗卡平的联合剂。单用受体阻滞剂治疗血压计不可控POAG患者的临床疗效和局部耐受性比较(双中心研究)。
B Boles Carenini, B Brogliatti, M T Dorigo, G Vadalà, R Protti, A Bellone
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引用次数: 0
期刊
Acta ophthalmologica Scandinavica. Supplement
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