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Cognitive Assessment of Young Adults Before and After Initiation of Combination Antiretroviral Therapy. 对开始接受抗逆转录病毒联合疗法前后的年轻人进行认知评估。
Pub Date : 2022-09-26 eCollection Date: 2022-09-01 DOI: 10.36519/idcm.2022.154
Özlem Gül, Alper Gündüz, Dilek Yıldız Sevgi, Nazife Duygu Demirbaş, Nuray Uzun, İlyas Dökmetaş

Objective: In the determination and monitoring of neurocognitive disorders in human immunodeficiency virus (HIV)-positive individuals, there is a need for significantly more practical methods which provide results in a shorter time than the tests that require challenging and specialized expertise. This study aimed to evaluate cognitive functions and the factors affecting them in naïve HIV-positive patients using by Montreal Cognitive Assessment (MoCA) test before and after the initiation of combination antiretroviral therapy.

Materials and methods: HIV-positive, treatment-naïve patients monitored between January-June 2017 were included in the study. The MoCA test was performed at the beginning and the sixth month of the treatment.

Results: Forty male patients were included in the study. The mean age was calculated as 29.1±4.0. When the factors affecting the MoCA score were examined, there was a significant relationship between the education level and the MoCA score. Smoking, using alcohol, and substance did not have a significant impact on baseline MoCA values. A significant correlation was found between cluster differentiation 4 (CD4) count and HIV RNA level and attention function. There was a significant increase in the total MoCA score and the MoCA subgroup scores at the end of the sixth month of the treatment.

Conclusion: MoCA test is one of the most practical tests that can be applied in a short time period, and it was found useful in evaluating the changes in the cognitive functions of HIV-positive patients during antiretroviral treatment.

目的:在确定和监测人类免疫缺陷病毒(HIV)抗体阳性者的神经认知障碍方面,与需要具有挑战性和专业知识的测试相比,我们需要能在更短时间内提供结果的更为实用的方法。本研究旨在通过蒙特利尔认知评估(MoCA)测试,评估HIV阳性新患者在开始联合抗逆转录病毒疗法前后的认知功能及其影响因素。在治疗开始和第六个月进行了MoCA测试:研究共纳入 40 名男性患者。平均年龄为(29.1±4.0)岁。在研究影响 MoCA 评分的因素时,教育程度与 MoCA 评分有显著关系。吸烟、酗酒和服用药物对MoCA基线值无明显影响。集群分化 4(CD4)计数和 HIV RNA 水平与注意力功能之间存在明显的相关性。在治疗的第六个月末,MoCA总分和MoCA亚组得分均有明显提高:MoCA测试是最实用的测试之一,可在短时间内应用,对评估HIV阳性患者在抗逆转录病毒治疗期间认知功能的变化非常有用。
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引用次数: 0
Population studies ofCavelerius saccharivorus Okajima (Heteroptera: Lygaeidae): Adult dispersal in relation to the density 冈岛糖化小仓鼠种群研究(异翅目:小仓鼠科):成虫分布与密度的关系
Pub Date : 2007-01-01 DOI: 10.1007/BF02754089
M. Murai
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引用次数: 5
A simulation model of the arrowhead scale population of a citrus tree in relation to control programmes (II): Dispersal of the scale and the amount of petroleum oil 柑橘树箭头蚧种群与防治方案的模拟模型(II):蚧的扩散和石油的量
Pub Date : 2007-01-01 DOI: 10.1007/BF02754101
Tamiji Inoue, R. Ohgushi
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引用次数: 0
A sequential estimation technique for capture-recapture censuses 捕获-再捕获人口普查的顺序估计技术
Pub Date : 2007-01-01 DOI: 10.1007/BF02754092
E. Kuno
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引用次数: 0
Population dynamics ofMalacosoma neustria testacea (Lepidoptera: Lasiocampidae): Stabilizing process in a field population 鳞翅目:绵蚧科(malacosoma neustria testacea)种群动态:野外种群稳定过程
Pub Date : 2007-01-01 DOI: 10.1007/BF02754100
M. Shiga
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引用次数: 1
Analysis of spatial association between two species based on the interspecies mean crowding 基于种间平均拥挤度的两种空间关联分析
Pub Date : 2007-01-01 DOI: 10.1007/BF02754097
S. Iwao
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引用次数: 17
Harvesting strategies, control styles and information levels: A study of planned disturbances to a population 收获策略、控制方式和信息水平:对种群的有计划干扰的研究
Pub Date : 2007-01-01 DOI: 10.1007/BF02754090
W. Thompson, W. Wellington, I. Vertinsky, E. M. Matsumura
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引用次数: 1
δ15N examination of the Lindeman-Hutchinson-Peters theory of increasin omnivory with trophic height in aquatic foodwebs 林德曼-哈钦森-彼得斯关于水生食物网中营养高度增加的杂食性增加理论的δ15N检验
Pub Date : 2007-01-01 DOI: 10.1007/BF02765257
R. France
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引用次数: 10
Generation carryover of a fraction of population members as an animal adaptation to unstable environmental conditions 作为动物对不稳定环境条件的适应,一小部分种群成员的世代延续
Pub Date : 2007-01-01 DOI: 10.1007/BF02754096
F. Takahashi
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引用次数: 5
Maternal age as a source of variation in the ability of an aphid to produce dispersing forms 作为蚜虫产生分散形式能力变异来源的母体年龄
Pub Date : 2007-01-01 DOI: 10.1007/BF02754093
P. A. Mackay, W. Wellington
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引用次数: 1
期刊
Researches on population ecology
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