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Effect of bisphosphonates on the risk of surgical site infection after anterior cervical discectomy and fusion (ACDF) in postmenopausal women with osteoporosis. 双膦酸盐对绝经后骨质疏松症妇女前路颈椎椎间盘切除术融合术后手术部位感染的影响。
IF 2.7 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2026-04-18 DOI: 10.1186/s12905-026-04466-3
Weilin Zhang, Boyuan Zhou, Canchang Chen, Dao Feng, Junyi Zhang, Zhencong Li, Jinguo Liang, Shengbang Huang, Zhiwen Dai, Cheng Luo, Jinsong Wei
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引用次数: 0
The association of fungal infection in cervical cancer: a systematic review and meta-analysis. 真菌感染与宫颈癌的关系:系统综述和荟萃分析。
IF 2.7 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2026-04-17 DOI: 10.1186/s12905-026-04451-w
Yunlai Wu, Yidan Zhang, Xinxin Qian, Yu Li

Background: Emerging evidence suggests a potential link between the fungal mycobiome and carcinogenesis. However, the relationship between fungal infection and cervical cancer progression remains inconclusive. This meta-analysis aimed to determine the pooled prevalence of fungal infection across different cervical pathological stages and assess its association with cervical lesions and HPV infection. PROSPERO CRD42024588513 is the registration number for the systematic review.

Methods: We conducted a systematic review and meta-analysis in accordance with PRISMA guidelines. We systematically searched PubMed, Web of Science, and Embase for studies published between January 1, 2004, and December 1, 2025. Observational studies (cross-sectional, case-control, cohort) with sample sizes ≥ 100 were included. Two reviewers independently performed study selection, data extraction, and quality assessment using the Newcastle-Ottawa Scale. Pooled prevalence and odds ratios (ORs) with 95% confidence intervals (CIs) were calculated using random-effects models in STATA.

Results: Seventeen studies involving 97,382 patients with cervical lesions and 450,724 controls were included. The overall pooled prevalence of fungal infection was significantly higher in cervical cancer patients (19%, 95% CI: 0.07-0.30) compared to non-cancer patients (8%, 95% CI: 0.06-0.10). In patients with precancerous lesions (CIN1, CIN2/3), the fungal infection rate was similar to that in normal controls (NILM). Subgroup analysis among non-NILM patients revealed a higher risk of fungal infection in HPV-positive individuals than in HPV-negative individuals (OR = 1.39, 95% CI: 1.07-1.81). Meta-regression identified geographic region (Europe) as a significant source of heterogeneity.

Conclusions: Fungal infection was more prevalent in invasive cervical cancer than in precancerous lesions or normal cervix, suggesting a potential association with late-stage carcinogenesis rather than early initiation. The observed association between fungal infection and HPV-positive status warrants further investigation. These findings highlight the need for prospective studies to clarify the role of the cervical mycobiome in cervical cancer progression.

背景:新出现的证据表明真菌菌群与致癌之间存在潜在联系。然而,真菌感染与宫颈癌进展之间的关系仍不确定。本荟萃分析旨在确定不同宫颈病理阶段真菌感染的总患病率,并评估其与宫颈病变和HPV感染的关系。PROSPERO CRD42024588513是系统评价的注册号。方法:我们按照PRISMA指南进行了系统回顾和荟萃分析。我们系统地检索了PubMed、Web of Science和Embase在2004年1月1日至2025年12月1日之间发表的研究。纳入样本量≥100的观察性研究(横断面、病例对照、队列)。两位审稿人使用纽卡斯尔-渥太华量表独立进行研究选择、数据提取和质量评估。在STATA中使用随机效应模型计算合并患病率和95%置信区间(ci)的优势比(ORs)。结果:纳入17项研究,涉及97,382例宫颈病变患者和450,724例对照。与非癌症患者(8%,95% CI: 0.06-0.10)相比,宫颈癌患者真菌感染的总体总患病率明显更高(19%,95% CI: 0.07-0.30)。在癌前病变患者(CIN1, CIN2/3)中,真菌感染率与正常对照组(NILM)相似。非nilm患者的亚组分析显示hpv阳性个体的真菌感染风险高于hpv阴性个体(OR = 1.39, 95% CI: 1.07-1.81)。元回归发现地理区域(欧洲)是异质性的重要来源。结论:真菌感染在侵袭性宫颈癌中比在癌前病变或正常子宫颈中更为普遍,提示真菌感染与晚期癌变有关,而不是早期癌变。观察到的真菌感染与hpv阳性状态之间的关联值得进一步调查。这些发现强调需要前瞻性研究来阐明宫颈癌分枝菌群在宫颈癌进展中的作用。
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引用次数: 0
Isolated axillary metastasis from early-stage dMMR endometrial carcinoma: a case report and mini-review. 早期dMMR子宫内膜癌腋窝转移一例报告及回顾。
IF 2.7 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2026-04-14 DOI: 10.1186/s12905-026-04458-3
Yanying Yu, Xiaoyan Chang, Xiaorong Hou, Fuquan Zhang
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引用次数: 0
Association of exposure to organophosphate pesticides with reproductive lifespan. 有机磷农药暴露与生殖寿命的关系。
IF 2.7 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2026-04-14 DOI: 10.1186/s12905-026-04455-6
Xianli Zhou, Wanting Yu, Jinying Xie, Senyuan Huang, Yadou Zhan, Lina Cao, Xin Chen, Xuelan Li
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引用次数: 0
Beyond the placebo effect: a systematic review and a network meta-analysis of treatment strategies for vulvodynia. 超越安慰剂效应:外阴痛治疗策略的系统回顾和网络荟萃分析。
IF 2.7 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2026-04-14 DOI: 10.1186/s12905-026-04469-0
Arsenio Spinillo, Mattia Dominoni, Lara Tiranini, Chiara Cassani, Rossella Elena Nappi, Barbara Gardella
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引用次数: 0
"Self-burning is the only way to show how painful women's lives are". An qualitative study of the social context of suicidal self-burning among Iraqi Kurdish women. “自焚是展示女性生活有多痛苦的唯一方式”。伊拉克库尔德妇女自杀自焚的社会背景的定性研究。
IF 2.7 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2026-04-13 DOI: 10.1186/s12905-026-04397-z
Darya Rostam Ahmed, Jaafar O Ahmed, Karwan Kakabra Kakamad, Talar Jamal Rahim, Nashmeel Rasool HamahAmeen, Reinhard Heun
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引用次数: 0
The connection between nutrition education, behavior, and body composition in women following the Mediterranean diet: a sustainable approach. 遵循地中海饮食的妇女的营养教育、行为和身体组成之间的联系:一种可持续的方法。
IF 2.7 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2026-04-13 DOI: 10.1186/s12905-026-04454-7
Ayşe Nur Kahve, Suhide Bilge Horzum, Melda Kangalgil
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引用次数: 0
Multiple endocrine dysfunctions in twins with Wilson's disease: two case reports Deng et al. endocrine dysfunctions in Wilson's disease. Wilson氏病双胞胎多发性内分泌功能障碍:邓等报道2例Wilson氏病内分泌功能障碍。
IF 2.7 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2026-04-13 DOI: 10.1186/s12905-026-04381-7
Hong-Rong Deng, Song-Ying Lin, Fei-Ya Zhang, Jin-Hua Yan, Xin-Hua Li, Xu-Bin Yang
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引用次数: 0
Female sexual function, urinary incontinence, and sexual position use 5 years after bariatric surgery: a prospective cohort study. 减肥手术后5年女性性功能、尿失禁和性体位使用:一项前瞻性队列研究
IF 2.7 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2026-04-11 DOI: 10.1186/s12905-026-04461-8
Magdalena Sternau, Mateusz Czajkowski, Agata Błaczkowska, Monika Proczko-Stepaniak, Marcin Matuszewski
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引用次数: 0
Serum 25-hydroxyvitamin D levels among women newly diagnosed with breast cancer at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. 埃塞俄比亚亚的斯亚贝巴Tikur Anbessa专科医院新诊断为乳腺癌的妇女血清25-羟基维生素D水平
IF 2.7 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2026-04-11 DOI: 10.1186/s12905-026-04453-8
Mehari Meles, Gadissa Gutema, Melaku Tsegaye, Chala Bashea, Feyissa Challa, Demiraw Bikila, Gebremedhin Gebremicael, Tigst Getahun, Wossene Habtu, Mekdes Alem, Abebe Edao, Anna Carobene, Habteyes Hailu Tola
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引用次数: 0
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BMC Women's Health
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