Pub Date : 2026-10-01DOI: 10.1016/j.chest.2026.05.043
Xinyue Wang, Xinyi Xu, Lu Xiao
{"title":"Female Sex and Cough Severity in Hypersensitivity Pneumonitis: Frequency or Perception?","authors":"Xinyue Wang, Xinyi Xu, Lu Xiao","doi":"10.1016/j.chest.2026.05.043","DOIUrl":"https://doi.org/10.1016/j.chest.2026.05.043","url":null,"abstract":"","PeriodicalId":9782,"journal":{"name":"Chest","volume":"170 4","pages":"e133"},"PeriodicalIF":9.8,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149135189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-10-01DOI: 10.1016/j.chest.2026.05.038
Jonathan Huggins
{"title":"Characterizing the Clinical and Economic Impact of Invasive Mold Infection After Lung Transplantation.","authors":"Jonathan Huggins","doi":"10.1016/j.chest.2026.05.038","DOIUrl":"https://doi.org/10.1016/j.chest.2026.05.038","url":null,"abstract":"","PeriodicalId":9782,"journal":{"name":"Chest","volume":"170 4","pages":"993-995"},"PeriodicalIF":9.8,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149135213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-10-01Epub Date: 2026-05-22DOI: 10.1016/j.chest.2026.05.018
Roxana Sulica, Teresa De Marco, Jean M Elwing, Sonia Bartolome, Namita Sood
Management of critically ill patients with pulmonary hypertension presents significant clinical challenges. Regardless of the underlying etiology or chronicity of pulmonary hypertension, superimposed acute illness can precipitate decompensated right ventricular failure (RVF) and death. Hospitalization, particularly in the ICU, is associated with high mortality, with RVF serving as the direct or indirect cause in most cases. In this article, we will focus on the management of acute decompensated RVF in patients with known pulmonary arterial hypertension (PAH). ICU management of the patient with PAH with RVF centers on the recognition and treatment of potentially reversible precipitants for decompensation and supportive strategies to optimize right ventricular (RV) function. Key goals include maintaining adequate oxygenation and tissue perfusion, correcting electrolyte and other metabolic abnormalities, optimizing fluid balance and RV preload, enhancing RV contractility, and reducing RV afterload. Continuous monitoring of cardiac function is essential, as is identifying and treating potential complications (eg, arrhythmia, acute kidney injury). When RVF persists despite maximal medical therapy, extracorporeal life support may be considered as a bridge to recovery or transplantation. In patients with advanced disease, multidisciplinary discussions aligned with patient and family preferences should guide the goals of care. Integration of palliative care specialists to manage symptoms and support caregivers remains a critical component of comprehensive ICU management for patients with PAH.
{"title":"Managing a Critically Ill Patient With Pulmonary Arterial Hypertension.","authors":"Roxana Sulica, Teresa De Marco, Jean M Elwing, Sonia Bartolome, Namita Sood","doi":"10.1016/j.chest.2026.05.018","DOIUrl":"10.1016/j.chest.2026.05.018","url":null,"abstract":"<p><p>Management of critically ill patients with pulmonary hypertension presents significant clinical challenges. Regardless of the underlying etiology or chronicity of pulmonary hypertension, superimposed acute illness can precipitate decompensated right ventricular failure (RVF) and death. Hospitalization, particularly in the ICU, is associated with high mortality, with RVF serving as the direct or indirect cause in most cases. In this article, we will focus on the management of acute decompensated RVF in patients with known pulmonary arterial hypertension (PAH). ICU management of the patient with PAH with RVF centers on the recognition and treatment of potentially reversible precipitants for decompensation and supportive strategies to optimize right ventricular (RV) function. Key goals include maintaining adequate oxygenation and tissue perfusion, correcting electrolyte and other metabolic abnormalities, optimizing fluid balance and RV preload, enhancing RV contractility, and reducing RV afterload. Continuous monitoring of cardiac function is essential, as is identifying and treating potential complications (eg, arrhythmia, acute kidney injury). When RVF persists despite maximal medical therapy, extracorporeal life support may be considered as a bridge to recovery or transplantation. In patients with advanced disease, multidisciplinary discussions aligned with patient and family preferences should guide the goals of care. Integration of palliative care specialists to manage symptoms and support caregivers remains a critical component of comprehensive ICU management for patients with PAH.</p>","PeriodicalId":9782,"journal":{"name":"Chest","volume":" ","pages":"1260-1271"},"PeriodicalIF":9.8,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148004598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-10-01DOI: 10.1016/j.chest.2026.06.014
Martin Witzenrath
{"title":"Targeting C5a, a Good Thing Gone Bad in Viral ARDS.","authors":"Martin Witzenrath","doi":"10.1016/j.chest.2026.06.014","DOIUrl":"https://doi.org/10.1016/j.chest.2026.06.014","url":null,"abstract":"","PeriodicalId":9782,"journal":{"name":"Chest","volume":"170 4","pages":"987-989"},"PeriodicalIF":9.8,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149134554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-10-01DOI: 10.1016/j.chest.2026.06.020
Naomi Launders
{"title":"Severe Mental Illness and Cancer: Broad and Persistent Inequalities in Cancer Care.","authors":"Naomi Launders","doi":"10.1016/j.chest.2026.06.020","DOIUrl":"https://doi.org/10.1016/j.chest.2026.06.020","url":null,"abstract":"","PeriodicalId":9782,"journal":{"name":"Chest","volume":"170 4","pages":"1016-1017"},"PeriodicalIF":9.8,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149134647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-10-01DOI: 10.1016/j.chest.2026.06.045
Anne V Gonzalez, Douglas Arenberg
{"title":"Watch or Intervene?: Natural History and Treatment Decisions in Patients With Subsolid Lung Nodules.","authors":"Anne V Gonzalez, Douglas Arenberg","doi":"10.1016/j.chest.2026.06.045","DOIUrl":"https://doi.org/10.1016/j.chest.2026.06.045","url":null,"abstract":"","PeriodicalId":9782,"journal":{"name":"Chest","volume":"170 4","pages":"1013-1015"},"PeriodicalIF":9.8,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149134851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-10-01DOI: 10.1016/j.chest.2026.06.015
Marta Dąbrowska, Elżbieta M Grabczak
{"title":"Redefining Success in Chronic Cough: The Emerging Role of Cough Control.","authors":"Marta Dąbrowska, Elżbieta M Grabczak","doi":"10.1016/j.chest.2026.06.015","DOIUrl":"https://doi.org/10.1016/j.chest.2026.06.015","url":null,"abstract":"","PeriodicalId":9782,"journal":{"name":"Chest","volume":"170 4","pages":"996-997"},"PeriodicalIF":9.8,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149135298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-09-30DOI: 10.1016/j.chest.2026.09.085
Joanna Walsh, Jesse Y. Hsu, Erin Tully, Gina Hong
Allergic bronchopulmonary aspergillosis (ABPA) is a complication of cystic fibrosis (CF) that often requires treatment. Oral corticosteroids (OCS) are the first-line therapy; however, antifungals alone or in combination with OCS are commonly used despite limited data supporting their role.
{"title":"Comparing the real-world effectiveness of oral corticosteroids and antifungals for the treatment of allergic bronchopulmonary aspergillosis in cystic fibrosis","authors":"Joanna Walsh, Jesse Y. Hsu, Erin Tully, Gina Hong","doi":"10.1016/j.chest.2026.09.085","DOIUrl":"https://doi.org/10.1016/j.chest.2026.09.085","url":null,"abstract":"Allergic bronchopulmonary aspergillosis (ABPA) is a complication of cystic fibrosis (CF) that often requires treatment. Oral corticosteroids (OCS) are the first-line therapy; however, antifungals alone or in combination with OCS are commonly used despite limited data supporting their role.","PeriodicalId":9782,"journal":{"name":"Chest","volume":"14 1","pages":""},"PeriodicalIF":9.6,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149087074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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