Comprehensive psychiatry最新文献

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Corrigendum to Validation of the Camouflaging Autistic Traits Questionnaire Short Form (CATQ-SF). Comprehensive Psychiatry 135 (2024) Nov:135:152525 伪装自闭症特征问卷简表验证的勘误表。综合精神病学135 (2024)Nov:135:152525。

IF 4.2 2区医学 Q1 PSYCHIATRY

Comprehensive psychiatry

Pub Date : 2026-06-01 Epub Date: 2026-04-28 DOI: 10.1016/j.comppsych.2026.152703

Laura Hull , Will Mandy , Hannah Belcher , K.V. Petrides

引用次数: 0

Neuropsychological functions as trait markers in OCD: A 10-year follow-up study 神经心理功能作为强迫症的特征标记：一项10年随访研究。

IF 4.2 2区医学 Q1 PSYCHIATRY

Comprehensive psychiatry

Pub Date : 2026-06-01 DOI: 10.1016/j.comppsych.2026.152724

M. Puialto , J. Mar , P. Alonso , E. Real , L. Mar-Barrutia , J.M. Menchón , S. Bertolín , O. Ibarrondo , C. Segalàs

Background

The alterations in neuropsychological performance described in Obsessive-Compulsive Disorder (OCD) reflect dysfunctions of the neurobiological structures underlying the disorder. Cognitive functions are influenced by clinical variables and are considered a potential endophenotype of the disorder. Although OCD is a chronic illness, data regarding the course of cognitive impairment are scarce.

Methods

The present study assessed 60 OCD patients and 30 healthy controls (HC). Both groups were followed for a period of 10.6 years (range 5–18 years). Neuropsychological performance was assessed with a battery measuring executive subcomponents and non-verbal memory at baseline and after follow-up, using repeated-measures mixed models. Several clinical variables were also assessed in the patient group.

Results

At baseline, patients with OCD demonstrated significantly poorer performance on neuropsychological tests than HC. Overall, the patterns of specific executive processes (organizational strategies and working memory) and non-verbal memory remained unchanged during the follow-up period in both groups. A reduction in severity of depression and obsessive-compulsive symptomatology was observed at the end of follow-up in OCD patients. In the sample, female sex was associated with worse performance on certain executive functions, and age with greater impairment in non-verbal memory after a decade of follow-up.

Conclusions

OCD patients showed significant impairments on neuropsychological tests compared to HC at baseline. After follow-up, both groups showed a similar decline in neuropsychological performance, with no significant differences. These findings suggest that cognitive deficits in OCD remain stable over time and may reflect trait-like characteristics, and that sex may differentially affect cognitive performance with aging.

背景：强迫症（OCD）中描述的神经心理表现的改变反映了该疾病背后的神经生物学结构的功能障碍。认知功能受到临床变量的影响，被认为是该疾病的潜在内表型。虽然强迫症是一种慢性疾病，但有关认知障碍病程的数据很少。方法：对60例强迫症患者和30例健康对照进行评估。两组随访时间为10.6年（5-18年）。在基线和随访后，使用重复测量混合模型，通过电池测量执行子成分和非言语记忆来评估神经心理表现。在患者组中还评估了几个临床变量。结果：在基线时，强迫症患者在神经心理测试中的表现明显低于HC。总体而言，两组的具体执行过程（组织策略和工作记忆）和非言语记忆模式在随访期间保持不变。在强迫症患者随访结束时，观察到抑郁和强迫症症状严重程度的降低。在样本中，经过十年的跟踪调查，女性在某些执行功能上的表现较差，年龄在非语言记忆方面的损害更大。结论：与HC相比，强迫症患者在神经心理测试中表现出显著的损伤。随访后，两组在神经心理表现上都出现了类似的下降，但没有显著差异。这些发现表明，强迫症的认知缺陷随着时间的推移保持稳定，并可能反映出类似性格的特征，而性别可能会随着年龄的增长而不同地影响认知表现。

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引用次数: 0

Acceptability of DBS for psychiatric disorders by French psychiatrists: a network clustering analysis based on a mixed method study 法国精神病学家接受DBS治疗精神疾病：基于混合方法研究的网络聚类分析。

IF 4.2 2区医学 Q1 PSYCHIATRY

Comprehensive psychiatry

Pub Date : 2026-06-01 Epub Date: 2026-05-09 DOI: 10.1016/j.comppsych.2026.152707

Stephane Mouchabac , Vincent P. Martin , Arnaud Pouchon , Dihia Ikene , Florian Ferreri , Bruno Millet , Alexis Bourla , Mircea Polosan

Background

Deep brain stimulation (DBS) is an emerging intervention for treatment-resistant psychiatric disorders, particularly obsessive-compulsive disorder (OCD). Despite strong evidence of efficacy, its acceptability remains limited among psychiatrists, especially in France. Understanding professional attitudes is essential for its clinical integration.

Methods

We conducted a mixed-method study using the script method, combining qualitative item development with quantitative analysis through a self-administered online questionnaire. The survey, based on a multidimensional model of acceptability, assessed French psychiatrists' perceptions of DBS across dimensions such as utility, usability, reliability, risk, and professional culture. Data were analyzed using network clustering analysis, centrality metrics, and community detection, allowing exploration of structural relationships among acceptability factors. Subgroup analyses were conducted by gender, professional seniority, practice type, and theoretical orientation.

Results

Among 418 respondents, the most central determinant of DBS acceptability was adherence to professional guidelines. Other influential factors included perceived utility, self-acceptability, and the classification of DBS as part of psychiatry's therapeutic arsenal. Peripheral concerns, such as cost or multidisciplinary logistics, were weakly connected to the core network. Gender and seniority influenced network structure: male psychiatrists showed stronger associations between adherence to professional guidelines and viewing DBS as a legitimate psychiatric treatment, while senior psychiatrists exhibited denser patterns of associations between acceptability-related factors. No significant differences were found by practice type or theoretical orientation.

Conclusions

DBS acceptability among French psychiatrists hinges on institutional validation and perceived alignment with psychiatric norms. These findings highlight the need for guideline-based dissemination strategies and tailored communication to support the ethical and effective adoption of DBS in psychiatric care.

背景：脑深部刺激（DBS）是治疗难治性精神障碍，特别是强迫症（OCD）的一种新兴干预手段。尽管有强有力的证据证明其有效性，但其在精神科医生中的可接受性仍然有限，尤其是在法国。了解职业态度对其临床整合至关重要。方法：采用脚本法，采用定性项目开发与定量分析相结合的方法，采用自填式在线问卷进行研究。该调查基于可接受性的多维模型，评估了法国精神科医生对DBS的看法，包括实用性、可用性、可靠性、风险和专业文化。数据分析使用网络聚类分析，中心性指标和社区检测，允许探索可接受因素之间的结构关系。按性别、专业年资、执业类型、理论取向进行分组分析。结果：在418名受访者中，DBS可接受性的最核心决定因素是遵守专业指南。其他影响因素包括感知效用、自我接受性以及将DBS分类为精神病学治疗手段的一部分。外围问题，如成本或多学科物流，与核心网络的联系很弱。性别和资历影响网络结构：男性精神科医生在遵守专业指南和将DBS视为一种合理的精神治疗之间表现出更强的联系，而资深精神科医生在可接受性相关因素之间表现出更紧密的联系。实践类型和理论取向没有显著差异。结论：DBS在法国精神病学家中的可接受性取决于机构验证和与精神病学规范的感知一致性。这些发现强调需要基于指南的传播策略和量身定制的沟通，以支持在精神病学护理中有效地采用DBS。

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引用次数: 0

Hooked on our devices: Problematic internet use as a contemporary mental health challenges 沉迷于我们的设备：有问题的互联网使用是当代心理健康挑战。

IF 4.2 2区医学 Q1 PSYCHIATRY

Comprehensive psychiatry

Pub Date : 2026-06-01 Epub Date: 2026-05-05 DOI: 10.1016/j.comppsych.2026.152706

Konstantinos Ioannidis

引用次数: 0

A dialectical perspective on smartphone use in borderline personality disorder: Communication fosters inner tension and dissociation, while entertainment provides momentary relief 边缘型人格障碍患者智能手机使用的辩证视角：交流助长了内心的紧张和分离，而娱乐提供了短暂的缓解。

IF 4.2 2区医学 Q1 PSYCHIATRY

Comprehensive psychiatry

Pub Date : 2026-06-01 Epub Date: 2026-05-23 DOI: 10.1016/j.comppsych.2026.152717

Ana Macchia , Dimitri Löchner , Ann-Christin Haag , Christian Montag , Birgit Abler

While digital phenotyping has shown potential in linking smartphone use to mental health, there is no evidence on how specific smartphone behaviors are associated with symptom dynamics in borderline personality disorder (BPD) in real time. This study examines how communication versus entertainment app use relates to inner tension and state dissociation, both in terms of momentary associations within individuals and in terms of average associations across individuals.

We tracked smartphone use in 49 individuals with BPD during an 8-week inpatient Dialectical Behavior Therapy and concurrently assessed inner tension and state dissociation every two hours. For up to 56 treatment days, we recorded hourly app session usage duration and frequency for communication (e.g., WhatsApp) and entertainment (e.g., Netflix), along with phone calls. Between-person associations based on mean scores for inner tension, state dissociation, and smartphone usage were examined with Spearman correlations. We investigated within-person momentary associations per hour with linear mixed models applied to the first 21 treatment days with sufficient data.

Higher mean inner tension levels were linked to longer daily use of communication apps. We found an association between a greater average number of incoming, but not outgoing, phone calls and higher mean levels of inner tension and state dissociation. Within-person analyses related a longer use of entertainment applications to reduced inner tension, but not dissociation, both at the category and at the app level (Netflix and YouTube). In contrast, more frequent communication app uses increased state inner tension and dissociation, which was mirrored in app-level analyses with WhatsApp.

Our findings are consistent with a dialectical perspective of smartphone use in BPD: While passive entertainment may represent an adaptive short-term self-regulation strategy, smartphone communication may trigger BPD-related emotional or dissociative responses.

Trial registration: https://osf.io/dfq9y/?view_only=4c19b891bb6448009b22f60b2552bd73.

虽然数字表型已经显示出将智能手机使用与心理健康联系起来的潜力，但没有证据表明特定的智能手机行为如何与边缘型人格障碍（BPD）的症状动态实时相关。本研究考察了交流与娱乐应用的使用与内部紧张和状态分离之间的关系，包括个体内部的瞬时联系和个体之间的平均联系。在为期8周的辩证行为治疗期间，我们追踪了49名BPD患者的智能手机使用情况，同时每两小时评估一次内部紧张和状态分离。在长达56天的治疗中，我们记录了每小时的应用程序会话使用时间和频率，用于通信（例如WhatsApp）和娱乐（例如Netflix），以及电话。基于内部紧张、状态分离和智能手机使用平均分数的人际关联用Spearman相关性进行了检验。我们用线性混合模型研究了前21天治疗期间每小时的人内瞬时关联，数据充足。较高的平均内心紧张水平与每天使用通信应用程序的时间更长有关。我们发现，接听电话的平均数量越大，而接听电话的平均数量越少，内心紧张和状态分离的平均水平越高，这两者之间存在关联。个人内部分析表明，长时间使用娱乐应用程序会减少内心紧张，但在类别和应用程序层面（Netflix和YouTube）上都不会。相比之下，更频繁地使用通信应用程序会增加状态内部紧张和分离，这在WhatsApp的应用程序级分析中得到了反映。我们的研究结果与BPD患者使用智能手机的辩证观点一致：虽然被动娱乐可能代表一种适应性的短期自我调节策略，但智能手机交流可能引发与BPD相关的情绪或分离反应。试验注册：https://osf.io/dfq9y/?view_only=4c19b891bb6448009b22f60b2552bd73。

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引用次数: 0

Selective attention in adults with major depressive disorder: A systematic review and meta-analysis of task-specific differences and negative bias 成人重度抑郁症患者的选择性注意：任务特异性差异和负偏倚的系统回顾和荟萃分析。

IF 4.2 2区医学 Q1 PSYCHIATRY

Comprehensive psychiatry

Pub Date : 2026-06-01 Epub Date: 2026-05-20 DOI: 10.1016/j.comppsych.2026.152720

Jessica K. Hur , Natalie C.W. Ho , Marta M. Maslej , Paul W. Andrews , Meryl A. Butters , Bruce Milliken , Benoit H. Mulsant

Several studies report that adults with Major Depressive Disorder (MDD) present with a negative attentional bias compared to individuals without a history of MDD. We conducted a systematic review and meta-analysis to: evaluate the hypothesis that selective attention differs in adults with MDD; determine whether this difference consists of a negative attentional bias (e.g., paying more attention to negative stimuli); and assess whether it is more severe with more severe MDD. Following PRISMA guidelines, we conducted a literature search of MEDLINE, PsycINFO, and EMBASE from inception through April 11, 2025, supplemented by manual searches, to identify published peer-reviewed manuscripts in English, French, or Korean comparing measures of selective attention in adults with MDD and non-psychiatric controls (HC). Results were synthesized narratively, and measures of selective attention in studies that used some versions of the Stroop task, or the dot-probe task were extracted and meta-analyzed. Of the 87 included studies, 73 (83.9%) showed a difference in selective attention (with 40 of 54 [74.1%] showing a negative bias) in adults with MDD compared to HC. Qualitatively, attention was impaired in the MDD group compared to HCs with all tasks. However, a significant difference in attention and negative bias was observed only with the dot-probe task in quantitative synthesis. Given the small number of relevant studies, power to identify moderators was limited. Age significantly moderated negative attentional bias for the dot-probe task, which increased with age. Future larger, higher-powered studies are needed to confirm selective attention differences in MDD and identify additional moderators.

一些研究报告称，与没有重度抑郁症病史的个体相比，患有重度抑郁症（MDD）的成年人表现出负性注意偏倚。我们进行了一项系统回顾和荟萃分析，以评估成人重度抑郁症患者的选择性注意不同的假设；确定这种差异是否由负性注意偏差（例如，对负性刺激给予更多关注）构成；并评估重度抑郁症是否更严重。遵循PRISMA指南，我们进行了MEDLINE， PsycINFO和EMBASE的文献检索，从开始到2025年4月11日，辅以人工检索，以确定已发表的同行评审的英文，法文或韩文手稿，比较成年MDD患者和非精神病学对照（HC）的选择性注意措施。对结果进行综合叙述，并对使用某些版本的Stroop任务或点探测任务的研究中选择性注意的测量进行提取和荟萃分析。在纳入的87项研究中，73项（83.9%）研究显示成人重度抑郁症患者与HC患者在选择性注意方面存在差异（54项研究中有40项（74.1%）显示负偏倚）。从质量上讲，与hc相比，MDD组在所有任务中的注意力都受到了损害。然而，只有在定量综合的点探针任务中，注意和负偏倚才有显著差异。由于相关研究数量较少，确定调节因子的能力有限。年龄显著调节点探测任务的负性注意偏倚，负性注意偏倚随年龄增加而增加。未来需要更大规模、更有力的研究来证实重度抑郁症的选择性注意差异，并确定其他调节因素。

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引用次数: 0

“When is it late”? Optimal threshold for duration of untreated illness (DUI) to predict SSRI-treatment resistance in obsessive-compulsive disorder (OCD) “什么时候晚？”未治疗疾病持续时间（DUI）预测强迫症（OCD）患者抗ssri治疗的最佳阈值

IF 4.2 2区医学 Q1 PSYCHIATRY

Comprehensive psychiatry

Pub Date : 2026-04-01 Epub Date: 2026-05-01 DOI: 10.1016/j.comppsych.2026.152680

L. Pellegrini , A. Paci , G. Di Salvo , G. Maina , U. Albert

引用次数: 0

Digital engagement profiles and binge eating symptoms in adolescents: A person-centred, longitudinal analysis 青少年的数字参与概况和暴食症状：一项以人为中心的纵向分析。

IF 4.2 2区医学 Q1 PSYCHIATRY

Comprehensive psychiatry

Pub Date : 2026-04-01 Epub Date: 2026-04-07 DOI: 10.1016/j.comppsych.2026.152694

Taylor Brown , Vanessa Tanti , Natasha Wilson , Mark D. Griffiths , Dan Lubman , Kaiden Hein , Vasileios Stavropoulos

Background

Binge eating symptoms emerge in early adolescence and are clinically meaningful below diagnostic thresholds. Digital media engagement may be relevant, yet most studies rely on aggregate screen time and rarely separate patterns of use from addiction-like features. This study tested whether screen use profiles and social media addiction risk were associated with binge eating symptom indicators in a large longitudinal cohort.

Methods

Data were drawn from the Adolescent Brain Cognitive Development (ABCD) Study at Time 3 (T3; n = 10,465; ages 10–13 years) and Time 5 (T5; n = 9257; ages 12–16 years). Latent profile analysis of six screen modalities derived screen use profiles. Social media addiction risk was classified using the Social Media Addiction Questionnaire. Four binge eating symptom indicators were assessed at each wave using item-level data from the Kiddie Schedule for Affective Disorders and Schizophrenia. Binomial logistic regression models tested associations, adjusting for sex, family conflict, and school environment.

Results

Two profiles were supported: High Screen Usage (44.5%) and Low Screen Usage (55.5%). At T3, High Screen Usage and higher social media addiction risk were each associated with higher odds of all symptom indicators after adjustment. At T5, High Screen Usage remained associated with binge-related distress, binge eating behaviour, and recurrent binge eating, while social media addiction risk differentiated all four symptoms. Family conflict showed the strongest associations, whereas a more positive school environment was associated with lower odds of symptoms.

Conclusions

Higher overall screen engagement and addiction-like social media use were independently associated with binge eating symptoms across early to mid-adolescence. Social media addiction risk showed more consistent symptom differentiation than screen use profiles, suggesting engagement quality may be more clinically informative than duration.

背景：暴食症状出现在青春期早期，低于诊断阈值具有临床意义。数字媒体参与度可能与此相关，但大多数研究都依赖于总屏幕时间，很少将使用模式与成瘾特征分开。这项研究在一个大型纵向队列中测试了屏幕使用情况和社交媒体成瘾风险是否与暴饮暴食症状指标相关。方法：数据来自青少年大脑认知发展（ABCD）研究，时间3 （T3; n = 10,465；年龄10-13岁）和时间5 （T5; n = 9257；年龄12-16岁）。对六种筛查方式的潜在分析得出了筛查使用概况。使用社交媒体成瘾问卷对社交媒体成瘾风险进行分类。使用儿童情感障碍和精神分裂症时间表的项目水平数据，对每一波的四个暴食症状指标进行评估。二项逻辑回归模型检验相关性，调整性别、家庭冲突和学校环境。结果：支持两种配置文件：高屏幕使用率（44.5%）和低屏幕使用率（55.5%）。在T3时，高屏幕使用和较高的社交媒体成瘾风险均与调整后所有症状指标的较高几率相关。在T5阶段，高屏幕使用率仍然与暴饮暴食相关的痛苦、暴饮暴食行为和复发性暴饮暴食有关，而社交媒体成瘾风险区分了所有四种症状。家庭冲突表现出最强的相关性，而更积极的学校环境与较低的症状几率相关。结论：较高的整体屏幕参与度和成瘾性社交媒体使用与青春期早期至中期的暴饮暴食症状独立相关。社交媒体成瘾风险表现出比屏幕使用情况更一致的症状分化，这表明参与质量可能比持续时间更能提供临床信息。

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引用次数: 0

Brief intensive CBT for adolescents with obsessive-compulsive disorder: A 5-day add-on program 青少年强迫症的简短强化CBT：一个5天的附加项目

IF 4.2 2区医学 Q1 PSYCHIATRY

Comprehensive psychiatry

Pub Date : 2026-04-01 Epub Date: 2026-05-01 DOI: 10.1016/j.comppsych.2026.152681

Leonie Spring , Juliane Ball , Lukasz Smigielski , Susanne Walitza , Veronika Mailänder

引用次数: 0

Comparative efficacy and acceptability of intervenions for paediatric obsessive-compulsive disorder: Preliminary findings from a network meta-analysis 小儿强迫症干预措施的比较疗效和可接受性：来自网络荟萃分析的初步发现

IF 4.2 2区医学 Q1 PSYCHIATRY

Comprehensive psychiatry

Pub Date : 2026-04-01 Epub Date: 2026-05-01 DOI: 10.1016/j.comppsych.2026.152683

Damir Krinitski , Susanne Walitza , Nadine Kirchen , Lukasz Smigielski

引用次数: 0

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