Pub Date : 2019-01-23DOI: 10.2174/2211556007666180420124544
B. Gorain, H. Choudhury, Manisha Pandey, Hasbi Laili Bt Mohd Zaki, Nuurul Izzati Bt Bakar, Nur Hanis Hamdhan, Nor Aniza Bt Musa, Nurul Fadhilah Bt Mustafa, Jaya Sree Sangkari, Nur Ain Athirah Bt Azmi, Lui Park Yeang, P. Kesharwani
{"title":"Mechanistic Description of Natural Herbs in the Treatment of Dementia: A Systematic Review","authors":"B. Gorain, H. Choudhury, Manisha Pandey, Hasbi Laili Bt Mohd Zaki, Nuurul Izzati Bt Bakar, Nur Hanis Hamdhan, Nor Aniza Bt Musa, Nurul Fadhilah Bt Mustafa, Jaya Sree Sangkari, Nur Ain Athirah Bt Azmi, Lui Park Yeang, P. Kesharwani","doi":"10.2174/2211556007666180420124544","DOIUrl":"https://doi.org/10.2174/2211556007666180420124544","url":null,"abstract":"","PeriodicalId":10751,"journal":{"name":"Current Psychopharmacology","volume":"534 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76538183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-23DOI: 10.2174/2211556007666180309155102
Anil Kumar, Ruchika Mittal, A. Kaur
{"title":"Insulin Resistance in Diabetes: Present and Future Prospective of Treatment","authors":"Anil Kumar, Ruchika Mittal, A. Kaur","doi":"10.2174/2211556007666180309155102","DOIUrl":"https://doi.org/10.2174/2211556007666180309155102","url":null,"abstract":"","PeriodicalId":10751,"journal":{"name":"Current Psychopharmacology","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89222631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Neurochemical Imbalance in Epilepsy from Animal Model to Human","authors":"Mandeep Kumar, Puneet Kumar, Prashant Koshal, Sumit Jamwal","doi":"10.2174/2211556007666180522084412","DOIUrl":"https://doi.org/10.2174/2211556007666180522084412","url":null,"abstract":"","PeriodicalId":10751,"journal":{"name":"Current Psychopharmacology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79803185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-23DOI: 10.2174/2211556007666180622123924
R. Bala, D. Khanna
{"title":"Lycopene: Bright Red Nutraceutical for Health Benefits","authors":"R. Bala, D. Khanna","doi":"10.2174/2211556007666180622123924","DOIUrl":"https://doi.org/10.2174/2211556007666180622123924","url":null,"abstract":"","PeriodicalId":10751,"journal":{"name":"Current Psychopharmacology","volume":"62 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74820388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-23DOI: 10.2174/2211556007666180601100641
T. Kaur, Puneet Kumar, Sumit Jamwal
Traumatic brain injury (TBI) is the leading cause of death and disability among children and young adults worldwide. These patients often have short and long term cognitive, behavioral and emotional impairments. The 5-HT2C and melatonin receptors are known to have involvement in memory functions. The aim of the present study is to find the beneficial effect of agomelatine (selective 5HT2C antagonist and melatonin receptor agonist) against weight drop induced traumatic brain injury in rats. The weight-drop model closely mimics the real life TBI. Injury was induced by dropping a weight of 450 gm from a height of 1 meter through a hollow metallic tube onto the exposed skull of rats under anesthesia. After 14 days of TBI the agomelatine (10, 20, and 40 mg/kg p.o. daily) treatment was given for next 14 days (i.e. till 28 th
{"title":"Protective Effect of Agomelatine on Traumatic Brain Injury Induced Cognitive Deficit in Rats: Possible Role of Neurotransmitters","authors":"T. Kaur, Puneet Kumar, Sumit Jamwal","doi":"10.2174/2211556007666180601100641","DOIUrl":"https://doi.org/10.2174/2211556007666180601100641","url":null,"abstract":"Traumatic brain injury (TBI) is the leading cause of death and disability among children and young adults worldwide. These patients often have short and long term cognitive, behavioral and emotional impairments. The 5-HT2C and melatonin receptors are known to have involvement in memory functions. The aim of the present study is to find the beneficial effect of agomelatine (selective 5HT2C antagonist and melatonin receptor agonist) against weight drop induced traumatic brain injury in rats. The weight-drop model closely mimics the real life TBI. Injury was induced by dropping a weight of 450 gm from a height of 1 meter through a hollow metallic tube onto the exposed skull of rats under anesthesia. After 14 days of TBI the agomelatine (10, 20, and 40 mg/kg p.o. daily) treatment was given for next 14 days (i.e. till 28 th","PeriodicalId":10751,"journal":{"name":"Current Psychopharmacology","volume":"290 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77772865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-03-31DOI: 10.2174/2211556007666180126112405
Pravin Kumar, B. Devi, Bhumika Thakur, M. Ashawat
{"title":"Colon Targeted Press Coated Tablets of Venlafaxine Hydrochloride for Treatment of Depression","authors":"Pravin Kumar, B. Devi, Bhumika Thakur, M. Ashawat","doi":"10.2174/2211556007666180126112405","DOIUrl":"https://doi.org/10.2174/2211556007666180126112405","url":null,"abstract":"","PeriodicalId":10751,"journal":{"name":"Current Psychopharmacology","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84024519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-03-31DOI: 10.2174/2211556007666180402143023
D. Patel, Katie Udenberg, P. Choi, Neelkamal Soares
Background: Selective serotonin reuptake inhibitors are the recommended and most commonly used antidepressant medications for children and adolescents. This class of medications has been considered generally safe with few significant treatment emergent adverse reactions that generally abate over time. All antidepressants carry the precautionary warning for potential increase in suicidal ideation and close monitoring is recommended. Management of side effects of this widely used class of drugs is an important aspect of any medical practice that cares for children and adolescents. Objective: To provide a succinct and clinically relevant review of side effects of SSRIs and their management in clinical practice. Method: A literature search was done of relevant published articles in English language in the Medline database. Results and Conclusion: Gastrointestinal side effects are most common with the use of SSRIs and generally are tolerable and do not need discontinuation of the medication. Cardiovascular side effects are uncommon; however, prolonged QT syndrome has been reported. In utero exposure results in a constellation of signs and symptoms in the newborn called poor neonatal adaptation syndrome. In utero exposure also is associated with teratogenicity. Although less frequent, symptoms suggesting behavioral activation, switching, serotonin syndrome and discontinuation or withdrawal syndrome need careful evaluation and management. A R T I C L E H I S T O R Y Received: June 05, 2017 Revised: March 12, 2018 Accepted: March 13, 2018
背景:选择性血清素再摄取抑制剂是儿童和青少年推荐和最常用的抗抑郁药物。这类药物通常被认为是安全的，几乎没有显著的治疗，出现的不良反应通常随着时间的推移而减轻。所有抗抑郁药都附有自杀意念可能增加的预防警告，建议密切监测。这类广泛使用的药物的副作用的管理是任何医疗实践的一个重要方面，照顾儿童和青少年。目的:对ssri类药物的不良反应及其在临床应用中的处理进行综述。方法:在Medline数据库中检索相关已发表的英文文献。结果和结论:胃肠道副作用是使用SSRIs最常见的，通常是可耐受的，不需要停药。心血管副作用不常见;然而，延长QT综合征也有报道。在子宫内暴露导致新生儿出现一系列体征和症状，称为新生儿适应不良综合征。在子宫内接触也与致畸性有关。虽然不太常见，但提示行为激活、转换、血清素综合征和停药或戒断综合征的症状需要仔细评估和管理。A R T I C L E H I S T O R Y收稿日期:2017年6月05日修稿日期:2018年3月12日收稿日期:2018年3月13日
{"title":"Management of Side-Effects of Selective-Serotonin Re-Uptake Inhibitors in Children and Adolescents","authors":"D. Patel, Katie Udenberg, P. Choi, Neelkamal Soares","doi":"10.2174/2211556007666180402143023","DOIUrl":"https://doi.org/10.2174/2211556007666180402143023","url":null,"abstract":"Background: Selective serotonin reuptake inhibitors are the recommended and most commonly used antidepressant medications for children and adolescents. This class of medications has been considered generally safe with few significant treatment emergent adverse reactions that generally abate over time. All antidepressants carry the precautionary warning for potential increase in suicidal ideation and close monitoring is recommended. Management of side effects of this widely used class of drugs is an important aspect of any medical practice that cares for children and adolescents. Objective: To provide a succinct and clinically relevant review of side effects of SSRIs and their management in clinical practice. Method: A literature search was done of relevant published articles in English language in the Medline database. Results and Conclusion: Gastrointestinal side effects are most common with the use of SSRIs and generally are tolerable and do not need discontinuation of the medication. Cardiovascular side effects are uncommon; however, prolonged QT syndrome has been reported. In utero exposure results in a constellation of signs and symptoms in the newborn called poor neonatal adaptation syndrome. In utero exposure also is associated with teratogenicity. Although less frequent, symptoms suggesting behavioral activation, switching, serotonin syndrome and discontinuation or withdrawal syndrome need careful evaluation and management. A R T I C L E H I S T O R Y Received: June 05, 2017 Revised: March 12, 2018 Accepted: March 13, 2018","PeriodicalId":10751,"journal":{"name":"Current Psychopharmacology","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86595187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：