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Dermoscopy of Kaposiʼs Sarcoma presenting as Longitudinal Erythronychia 以纵向赤甲为表现的卡波西肉瘤的皮肤镜检查
Pub Date : 2019-04-23 DOI: 10.18689/mjcrs-1000138
Safae Zinoune, S. Gallouj, H. Baybay, S. Elloudi, M. Rimani, F. Mernissi
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引用次数: 1
Clear Cell Hidradenoma of the Inguinal Area: A Rare Tumor in an Uncommon Location 腹股沟透明细胞汗腺瘤:罕见部位的罕见肿瘤
Pub Date : 2019-04-18 DOI: 10.18689/MJCRS-1000136
Safae Zinoune, Z. Douhi, H. Baybay, S. Elloudi, M. Rimani, F. Mernissi
Nodular hidradenomas are benign sweat gland-derived tumors that can produce clinical and dermatoscopic misdiagnoses. Histologically, these tumors can be classified into eccrine and apocrine subtypes. Clear cell hidradenoma is a rare benign eccrine tumor, it’s representing 1% of all skin tumors, found mainly in adult females. The lesions are usually solitary and are most likely to be found on the scalp, face or anterior trunk. We report a case of clear cell hidradenoma developing in the inguinal area in a 68-year old man, which occurred during the course of nine months. The clinical and histologic findings of the tumor are documented. The lesion was totally removed by excision and revealed no evidence of recurrence. Through this case, we would like to highlight the unusual location of this hidradenoma.
结节性汗腺瘤是一种良性的汗腺源性肿瘤,可引起临床和皮肤镜误诊。组织学上,这些肿瘤可分为分泌型和顶泌型。透明细胞汗腺瘤是一种罕见的良性内分泌肿瘤,占所有皮肤肿瘤的1%,主要见于成年女性。病变通常是孤立的,最可能发生在头皮、面部或躯干前部。我们报告一例68岁男性腹股沟区透明细胞腺瘤的发展,发生在九个月的过程中。肿瘤的临床和组织学表现被记录下来。病灶完全切除,无复发迹象。通过这个病例,我们想强调这个汗腺瘤的不寻常的位置。
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引用次数: 0
Effect of Momoridica chorantia (Bitter Melon) Fruit extract on Homocysteine Levels and Lipid Profile in experimentally induced Hyperlipidemia in Rabbits 苦瓜提取物对实验性高脂血症家兔同型半胱氨酸水平和血脂的影响
Pub Date : 2019-04-18 DOI: 10.18689/mjcrs-1000135
J. Sethi, K. Dahiya
Material and methods: Albino rabbits (1.5-2.5 kg) of either sex were divided into three groups with six animals in each group. Group I received the standard chow diet; group II rabbits received HFD; and group III rabbits received HFD supplemented with aqueous MC fruit extract (100 mg/kg). After 14 weeks of the experimental period, animals were fasted overnight and blood was taken for estimation of total cholesterol (TC), triglyceride (TG), high density cholesterol (HDL-C) and homocysteine.
材料与方法:将1.5 ~ 2.5 kg雌雄白化兔随机分为3组,每组6只。第一组饲喂标准饲料;第二组兔接受HFD;III组在HFD的基础上添加枸杞果提取物(100 mg/kg)。实验14周后,禁食过夜,取血测定总胆固醇(TC)、甘油三酯(TG)、高密度胆固醇(HDL-C)和同型半胱氨酸。
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引用次数: 1
Melanoma of the Earlobe - An Uncommon location for An Usual Disease 耳垂黑色素瘤——一种常见疾病的罕见部位
Pub Date : 2019-04-08 DOI: 10.18689/MJCRS-1000134
Y. Barbach, M. Chaouche, Abdellah Dah Cherif, S. Elloudi, H. Baybay, F. Mernissi
It was a 55-year-old taxi driver with an antecedent of chronic solar exposure since childhood, admitted in our department for the management of a purple tumor on the right earlobe evolving for 6 months after handling a hair, painless and non-pruriginous. The dermatological examination showed the presence of a 4 cm purple tumor located at the right earlobe with infiltrated basis, and a small ulceration in the center, the dermoscopy objectified the presence of purple laguna separate by fibrous septas with an ulceration and a rainbow pattern, the diagnosis of angiokeratoma, epidermised botriomyoma or kaposi disease was evoked, other diagnosis was cutaneous metastasis of a renal or hepatic tumor or a melanoma. Histology with immuno histochemistry confirmed a nodular-type melanoma, an extension assessment was performed revealing pulmonary and hepatic metastasis, oncological management was preconized.
患者55岁,出租车司机,自小有慢性日晒病史,因右耳垂紫色肿瘤,处理毛发后发展6个月,无痛无瘙痒而入院。皮肤检查示:右侧耳垂有一4cm紫色肿瘤,基底浸润,中心有小溃疡,镜下见紫色沟沟,纤维间隔分隔,溃疡呈彩虹状,诊断为血管角化瘤、表皮性骨肌瘤或卡波西病,其他诊断为肾或肝肿瘤皮肤转移或黑色素瘤。免疫组织化学组织学证实为结节型黑色素瘤,扩展评估显示肺和肝转移,肿瘤治疗预先确定。
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引用次数: 0
What does Dermoscopy Say about Glomus Tumors? 皮肤镜检查对血管球瘤有何启示?
Pub Date : 2019-04-02 DOI: 10.18689/MJCRS-1000133
Y. Barbach, M. Chaouche, Abdellah Dah Cherif, S. Elloudi, H. Baybay, F. Mernissi
Glomus tumor is an uncommon tumor arising from the glomus cells. They are usually noted in subungal locations. They are extremely painful to pressure, exposure to cold, and even to touch [1]. The pain increases on application of pressure with the tip of a pencil over the precise area (Love’s sign) [2]. Treatment of choice for glomus tumor is surgical excision. Also, sclerotherapy as well as laser therapy with CO2, pulsed dye and Nd: YAG can be employed. Recurrences are noted due to local invasion of tumor [3]. Since the diagnosis of glomus tumors remains difficult to remember based on clinical criteria, dermoscopy can help. The dermoscopic finding previously reported in the literature include a discrete linear vascular structure on the nail plate and numerous telangiectasias ramified on the nail bed and matrix [4], an altered pigmentary network and a pinkish hue [5]. However, these results are not universal. In a recent report, instead of the pinkish hue, a homogeneous white discoloration of the nail plate was observed [6]. Thus, dermoscopy can be helpful in screening glomus tumor, however, the role of histopathological examination remains essential to make the diagnosis.
血管球瘤是一种由血管球细胞引起的罕见肿瘤。它们通常出现在趾下部位。它们对压力、暴露在寒冷中,甚至触摸都非常痛苦[1]。用铅笔尖在精确的区域(洛夫氏标志)上施加压力,疼痛会增加[2]。血管球瘤的治疗选择是手术切除。此外,硬化疗法以及激光治疗与二氧化碳,脉冲染料和Nd: YAG可以使用。肿瘤局部浸润可引起复发[3]。由于球囊瘤的诊断仍然难以记住基于临床标准,皮肤镜检查可以提供帮助。先前文献报道的皮肤镜检查结果包括甲板上离散的线性血管结构,甲床和甲基质上分叉的大量毛细血管扩张[4],色素网络改变和粉红色[5]。然而,这些结果并不普遍。在最近的一份报告中,观察到甲板呈均匀的白色变色,而不是粉红色[6]。因此,皮肤镜检查可以帮助筛选球囊瘤,然而,组织病理学检查的作用仍然是必不可少的,以作出诊断。
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引用次数: 1
Dermoscopy of Nail Fold Capillaries in Connective Tissue Diseases 结缔组织病甲襞毛细血管的皮肤镜检查
Pub Date : 2019-03-29 DOI: 10.18689/MJCRS-1000132
Y. Barbach, M. Chaouche, Abdellah Dah Cherif, S. Elloudi, H. Baybay, F. Mernissi
Materiels and Methods: We describe the dermoscopic periungual appearance of 153 patients followed for various systemic diseases in the dermatology department of CHU HASSAN II in Fes, while comparing our results with those of the literature. The examination was performed with a photofinder dermoscope then dermlite by simple transillumination of the cutaneous epithelium illuminated by the dermoscope light.
材料和方法:我们描述了在Fes朱哈桑二世皮肤科随访的153例全身疾病患者的皮肤镜下关节周围外观,并将我们的结果与文献进行了比较。检查是用照相皮肤镜进行的,然后用皮肤镜的光对皮肤上皮进行简单的透照。
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引用次数: 2
Cutaneous Tuberculosis: A still relevant Disease in Morocco (A Study of 146 Cases) 皮肤结核:摩洛哥仍存在的一种疾病(附146例分析)
Pub Date : 2019-03-22 DOI: 10.18689/mjcrs-1000131
Safae Zinoune, H. Baybay, I. Assenhaji, Mohammed Chaouche, Z. Douhi, Sara Elloudi, F. Mernissi
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引用次数: 0
Allografts in Periodontal Regeneration 牙周再生中的同种异体移植物
Pub Date : 2019-03-21 DOI: 10.18689/MJCRS-1000130
Punit Naidu
Bone allografts are being widely used in field of periodontology, many of clinicians are unfamiliar with their preparation and processing as well as their use as safe and effective graft materials. The major issues associated with these materials are antigenicity and risk of disease transmission from donor to recipient. To minimize the risk, the production of an allograft and its distribution and implantation requires strict attention to detail through a comprehensive process. With an increasing requirement in clinical practice for bone grafting procedures, there is an increase in patient’s demands for assurance that bank bone will not be infected with pathogens. To ensure the patients, surgeons should be able to cite factual information and recommendations by responsible organizations regarding safety of allografts. Knowledge of human bone allograft procurement, processing, and tracking may allow dentists to better educate patients and address concerns about this valuable treatment option. The purpose of this review is to update about the procurement, safety and efficacy of allografts.
同种异体骨移植在牙周病领域的应用越来越广泛,但对于同种异体骨移植的制备、加工以及作为一种安全有效的移植材料的使用,许多临床医生并不熟悉。与这些材料相关的主要问题是抗原性和从供体到受体的疾病传播风险。为了将风险降到最低,同种异体移植物的生产及其分布和植入需要通过一个全面的过程严格关注细节。随着临床对植骨手术的要求越来越高,患者对保证骨库不会被病原体感染的要求也越来越高。为了确保患者的安全,外科医生应该能够引用有关同种异体移植安全性的事实信息和相关组织的建议。了解人类同种异体骨移植的获取、处理和跟踪可以让牙医更好地教育患者,并解决对这种有价值的治疗选择的担忧。这篇综述的目的是更新关于同种异体移植物的获取,安全性和有效性。
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引用次数: 2
Leonine Facies: The Face of a Forgotten Disease Leonine相:一种被遗忘的疾病的面孔
Pub Date : 2019-03-18 DOI: 10.18689/MJCRS-1000129
Safae Zinoune, M. Chaouche, Z. Douhi, O. E. Jouari, S. Elloudi, H. Baybay, F. Mernissi
A 45-year-old woman presented with a five-year history of paresthesia of both hands and feet, along with modification of facial features. On physical examination, she had coarse ‘leonine like’ facies, with thickened skin of face and eyelids, her face had multiple nodular lesions that coalesced into plaques, especially on the forehead. She had madarosis and a saddle-nose (Figures 1 and 2). We also observed strabismus, ulcers on hands and feet with a swan neck deformity of fingers (Figures 3 and 4). After the strongly suggestive hypothesis of lepromatous leprosy, we performed a skin biopsy which confirmed the disease. The patient underwent standard anti-bacillary multidrug therapy for 12 months, with good improvement.
45岁女性,5年手脚感觉异常病史,伴有面部特征改变。体格检查,她有粗糙的“狮子样”相,面部和眼睑皮肤增厚,面部有多发结节病变合并成斑块,特别是在前额。她有骨质疏松和鞍鼻(图1和2)。我们还观察到斜视、手足溃疡和手指天鹅颈畸形(图3和4)。在强烈暗示麻风性麻风病的假设后,我们进行了皮肤活检,证实了该疾病。患者接受标准抗细菌多药治疗12个月,好转良好。
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引用次数: 0
Giant Primary Amelanotic Scalp Melanoma: Report of a Rare Case and Review of the Literature 巨大原发性无色素头皮黑色素瘤:一罕见病例报告及文献复习
Pub Date : 2019-03-18 DOI: 10.18689/MJCRS-1000128
Safae Zinoune, S. Elloudi, C. S. Hassani, L. Tahiri, H. Baybay, A. Oufkir, F. Mernissi
Giant Primary Amelanotic Scalp Melanoma: Report of a Rare Case and Review of the Literature Safae Zinoune1*, Sara Elloudi1, Cheymae Saadani Hassani1, Layla Tahiri2, Hannane Baybay1, Ayat Allah Oufkir3 and Fatima-Zahra Mernissi1 1Department of Dermatology and Venereology, Hassan II University Hospital, Fès, Morocco 2Department of Anatomic Pathology, Hassan II University Hospital, Fès, Morocco 3Department of Plastic Surgery, Hassan II University Hospital, Fès, Morocco
巨大原发性无色素性皮肤黑色素瘤:1例罕见病例报告及文献回顾Safae Zinoune1*, Sara Elloudi1, Cheymae Saadani Hassani1, Layla Tahiri2, Hannane Baybay1, Ayat Allah Oufkir3和Fatima-Zahra Mernissi1 1摩洛哥f斯哈桑二世大学医院皮肤性病科2摩洛哥f斯哈桑二世大学医院解剖病理科3摩洛哥f斯哈桑二世大学医院整形外科
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引用次数: 1
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Madridge Journal of Case Reports and Studies
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