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Nutritional screening among paediatric indigenous population in Malaysia: a pilot study 马来西亚土著儿童营养筛查:一项试点研究
Q4 PEDIATRICS Pub Date : 2023-08-28 DOI: 10.15557/pimr.2023.0015
Grace Ong Hui Yan, Jeyasakthy Saniasiaya, Jeyanthi Kulasegarah, Prepageran Narayanan
Introduction: Undernutrition is a serious health problem in developing countries. The prevalence of undernutrition is deemed higher among the indigenous community in many developing countries, owing to their relatively lower socioeconomic status, lack of healthcare awareness and essential needs, as well as poor sanitation facilities. We aimed to assess the nutritional status among children within a single indigenous community in Kampung Gabai, Malaysia. Materials and methods: We conducted a pilot study on the nutritional status of the paediatric population of the Orang Asli community in Kampung Gabai by assessingtheir anthropometric indices during a medical camp, as this community had never been assessed before. Anthropometric indices were based on heights, mid-upper arm circumferences and head circumferences of 21 children aged between 2 to 14 years. Additionally, skin evaluation and otoscopic examinations were performed in the same setting. Results: The prevalence of stunting was 38.1% among the children in Kampung Gabai. The height-for-age Z score distribution of the children skewed slightly to the left in comparison to the World Health Organization standard. The midupper-arm circumferences and the head circumferences of children who were less than 5 years old were within the normal range. The children generally had normal otoscopic and skin findings. Conclusion: This preliminary study concluded that the prevalence of stunting is high among indigenous children in a single community in Malaysia.
营养不良是发展中国家一个严重的健康问题。在许多发展中国家,由于土著社区的社会经济地位相对较低、缺乏保健意识和基本需求以及卫生设施差,营养不良的发生率较高。我们的目的是评估马来西亚甘榜加拜一个土著社区儿童的营养状况。材料和方法:我们对甘榜加贝(Kampung Gabai)原住民社区儿科人口的营养状况进行了一项试点研究,方法是在医疗营期间评估他们的人体测量指数,因为该社区以前从未进行过评估。人体测量指标基于21名2 - 14岁儿童的身高、中上臂围和头围。此外,皮肤评估和耳镜检查在同一环境下进行。结果:甘榜加贝县儿童发育迟缓患病率为38.1%。与世界卫生组织的标准相比,儿童的身高与年龄的Z分数分布略微向左倾斜。5岁以下儿童上臂中部围度及头部围度均在正常范围内。这些儿童的耳镜检查和皮肤检查结果一般正常。结论:这项初步研究得出结论,在马来西亚的一个社区中,土著儿童的发育迟缓患病率很高。
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引用次数: 0
Severe hypothyroidism as the cause of rhabdomyolysis and acute kidney injury – a case report 严重甲状腺功能减退导致横纹肌溶解和急性肾损伤1例
Q4 PEDIATRICS Pub Date : 2023-08-28 DOI: 10.15557/pimr.2023.0019
Adam Rytel, Katarzyna Morawiec, Monika Kukawska-Rytel, Elżbieta Głuch, Stanisław Niemczyk
Hypothyroidism is a set of clinical symptoms associated with a deficiency of thyroid hormones. Musculoskeletal symptoms, i.e. stiffness, pain or muscle fatigue, are among the many manifestations of the disorder. Rhabdomyolysis, a syndrome accompanying muscle tissue damage, which leads to acute kidney injury, may be a complication of hypothyroidism. In this paper, we present a case of a 35-year-old patient with hypothyroidism due to Hashimoto’s disease, with a 4-year history of diagnosis for periodic pain and muscle weakness in the lower extremities. The patient presented to the hospital due to the recurring symptoms. One month before admission, she had discontinued thyroid hormone supplementation. Laboratory tests showed unquantifiable low levels of free thyroid hormones, elevated creatine kinase levels, and elevated kidney function parameters. Non-compliance can lead to potentially life-threatening complications in hypothyroid patients. Prompt diagnosis and implementation of treatment can lead to symptom resolution.
甲状腺功能减退症是一组与甲状腺激素缺乏有关的临床症状。肌肉骨骼症状,即僵硬、疼痛或肌肉疲劳,是这种疾病的许多表现之一。横纹肌溶解是一种伴随肌肉组织损伤的综合征,可导致急性肾损伤,可能是甲状腺功能减退症的并发症。在本文中,我们提出了一个35岁的患者甲状腺功能减退症,由于桥本氏病,有4年的诊断史,周期性疼痛和下肢肌肉无力。病人因反复发作的症状而到医院就诊。入院前一个月,她已停止补充甲状腺激素。实验室检查显示无法量化的游离甲状腺激素水平低,肌酸激酶水平升高,肾功能参数升高。不遵医嘱可能导致甲状腺功能减退患者出现潜在的危及生命的并发症。及时诊断和实施治疗可导致症状的解决。
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引用次数: 0
Epiglottic mass mimicking laryngeal carcinoma: a red herring 会厌肿块模拟喉癌:转移注意力
Q4 PEDIATRICS Pub Date : 2023-08-28 DOI: 10.15557/pimr.2023.0022
Jeeven Velayutham, Jeyasakthy Saniasiaya
Aim: Laryngeal masses are commonly found during patient assessments in the otorhinolaryngology clinic and are almost always associated with a serious pathology, such as a malignancy, rather than a benign condition. In addition, epiglottic masses are often linked to a malignant disorder or granulomatous infection. Case report: Herein, we describe an immunocompromised patient presenting with respiratory distress secondary to an epiglottic mass requiring tracheostomy in view of airway compromise. A repeated histopathological examination revealed methicillin-resistant Staphylococcus aureus, which was successfully eradicated with long-term antibiotics. The tracheostomy was decannulated. Conclusion: We highlight the importance of early measures and interventions to obtain a diagnosis that will aid in patients’ management and recovery.
目的:喉部肿块在耳鼻喉科门诊的病人评估中很常见,并且几乎总是与严重的病理相关,如恶性肿瘤,而不是良性疾病。此外,会厌肿块常与恶性疾病或肉芽肿感染有关。病例报告:在此,我们描述了一名免疫功能低下的患者,由于会厌肿块导致呼吸窘迫,需要气管切开术。反复组织病理学检查显示耐甲氧西林金黄色葡萄球菌,成功根除长期抗生素。气管切开取管。结论:我们强调早期措施和干预的重要性,以获得诊断,这将有助于患者的管理和恢复。
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引用次数: 0
Congenital hypertrophy and lymphedema of the right upper limb in a child 儿童右上肢先天性肥大和淋巴水肿
Q4 PEDIATRICS Pub Date : 2023-08-28 DOI: 10.15557/pimr.2023.0020
Jose Maria Pereira de Godoy, Ana Carolina Pereira de Godoy
The aim of the present study was to report a case of congenital upper limb hypertrophy associated with lymphedema in a child. An eight-year-old girl presented with a history of right upper limb oedema since birth, which was more significant in the hand. Volumetry was performed, revealing 1,838 grams in the right arm and 1,483 grams in the left arm. Intensive treatment with the Godoy method® was proposed. Treatment involved five hours per day using the RAGodoy® device, 15 minutes of cervical lymphatic therapy, and three hours of manual lymphatic therapy per day. With treatment, the volume of the right arm was reduced to 1,663 grams (reduction of 205 grams). After treatment, hypertrophy of the limb was noticed, which had been aggravated by the lymphedema. Congenital hypertrophy of the upper limb is rare in children. Its association with lymphedema has not previously been reported in the literature and could cause diagnostic difficulties.
本研究的目的是报告一个儿童先天性上肢肥大伴淋巴水肿的病例。一个八岁的女孩提出了一个历史的右上肢水肿自出生以来,这是更显著的手。进行了体积测量,显示右臂有1838克,左臂有1483克。建议采用Godoy法®进行强化治疗。治疗包括每天5小时使用RAGodoy®装置,15分钟颈部淋巴治疗,每天3小时手动淋巴治疗。治疗后,右臂体积减少至1663克(减少205克)。治疗后发现肢体肥大,并因淋巴水肿加重。先天性上肢肥大在儿童中是罕见的。它与淋巴水肿的关系以前没有文献报道,可能导致诊断困难。
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引用次数: 0
The impact of childhood febrile urinary tract infection on urinary tract dilation in ultrasonography 小儿热性尿路感染对超声检查尿路扩张的影响
Q4 PEDIATRICS Pub Date : 2023-08-28 DOI: 10.15557/pimr.2023.0016
Magdalena Okarska-Napierała, Katarzyna Karpierz, Przemysław Bombiński, Piotr Majcher, Adam Waszkowski, Ernest Piotr Kuchar
Introduction and objective: Febrile urinary tract infection in a child may be the first manifestation of congenital anomalies of the kidneys and the urinary tract. Renal and bladder ultrasonography remains the first-line imaging modality in children with urinary tract infections. Urinary tract dilation found on ultrasonography prompts further invasive diagnosis; however, when performed in the acute phase of infection, it may potentially reveal misleading findings. Our study investigated whether acute urinary tract infection is associated with urinary tract dilatation and kidney oedema on ultrasonography. Materials and methods: We included 62 children up to 3 years of age with the first episode of febrile urinary tract infection in this prospective cohort study. We performed three ultrasonography examinations in each child: on the first day of the treatment, as well as two and four weeks after treatment onset. We scanned 124 kidneys. Results: The number of kidneys with urinary tract dilation has not significantly changed in consecutive ultrasound examinations. However, both renal length and width increased in the acute phase of urinary tract infection, correlating with symptom duration and C-reactive protein levels, and then subsided within 2–4 weeks. Conclusions: Febrile urinary tract infection does not significantly affect the results of renal and bladder ultrasonography for congenital anomalies of the kidneys and the urinary tract in children up to 3 years old. Kidneys are often involved in children with febrile urinary tract infections. Repeated ultrasound scans before further, more invasive diagnosis are recommended.
简介和目的:儿童发热性尿路感染可能是肾脏和尿路先天性异常的首要表现。肾脏和膀胱超声检查仍然是泌尿道感染儿童的一线成像方式。超声检查发现尿路扩张提示进一步侵入性诊断;然而,当在感染的急性期进行时,它可能会显示误导性的结果。本研究通过超声检查探讨急性尿路感染是否与尿路扩张和肾脏水肿有关。材料和方法:在这项前瞻性队列研究中,我们纳入了62名首次出现发热性尿路感染的3岁以下儿童。我们对每个孩子进行了三次超声检查:在治疗的第一天,以及治疗开始后的两周和四周。我们扫描了124个肾脏。结果:连续超声检查尿路扩张肾数无明显变化。但尿路感染急性期肾脏长度和宽度均增加,与症状持续时间和c反应蛋白水平相关,并在2-4周内消退。结论:发热性尿路感染对3岁以下儿童先天性肾、尿路异常的肾、膀胱超声检查结果无明显影响。儿童发热性尿路感染常累及肾脏。建议在进一步的侵入性诊断前重复超声扫描。
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引用次数: 0
Dysbiosis and allergy as a background of chronic rhinosinusitis in preschool children 学龄前儿童慢性鼻窦炎的生态失调和过敏背景
Q4 PEDIATRICS Pub Date : 2023-08-28 DOI: 10.15557/pimr.2023.0011
Katarzyna Molińska, Paweł Majak
Allergic diseases and chronic inflammatory diseases of the respiratory system, such as asthma or chronic rhinosinusitis, continue to pose a real challenge to modern medicine. The causes of the growing problem generated by these diseases is thought to be in the interaction of genes and the environment. In the light of current knowledge, it seems that the environmentally dependent interaction between the airway microbiota ecosystem and the epithelium is able to shape the functions of the local immune system, producing a number of molecular and clinical consequences. In this paper, an attempt was made to describe the role of microbiota composition disorders (dysbiosis) of the upper respiratory tract and allergies in the development of chronić rhinosinusitis in children. The research results obtained in a Polish cohort of young children diagnosed with chronic rhinosinusitis with or without concomitant asthma are summarised. Some of the children presented with features of secondary dysbiosis, which was associated with sensitisation to house dust mite allergens. It was noted that frequent courses of antibiotic therapy correlated with microbiota dysfunction, reducing biodiversity. It was also observed that patients suffering from asthma had specific dysbiosis in the upper respiratory tract. It is characterised by an altered proportion between the main types of bacteria and is expressed by a reduced Patescibacteria/Actinobacteria ratio, constituting an independent factor of asthma in the study group, similar to atopy and reduced perception of the sweet taste. An attempt was also made to identify possible therapeutic and prophylactic interventions to treat and prevent dysbiosis in children suffering from chronic rhinosinusitis.
过敏性疾病和呼吸系统的慢性炎症性疾病,如哮喘或慢性鼻窦炎,继续对现代医学构成真正的挑战。这些疾病造成的问题日益严重的原因被认为是基因和环境的相互作用。根据目前的知识,似乎气道微生物群生态系统和上皮之间的环境依赖性相互作用能够塑造局部免疫系统的功能,产生许多分子和临床后果。本文试图描述上呼吸道微生物群组成紊乱(生态失调)和过敏在儿童慢性鼻窦炎发展中的作用。本文总结了在波兰诊断为慢性鼻窦炎伴或不伴哮喘的幼儿队列中获得的研究结果。一些儿童表现出继发性生态失调的特征,这与室内尘螨过敏原致敏有关。值得注意的是,频繁的抗生素治疗与微生物群功能障碍相关,减少了生物多样性。还观察到哮喘患者在上呼吸道有特异性的生态失调。其特征是主要细菌类型之间的比例发生改变,并通过降低的Patescibacteria/放线菌比率来表达,这在研究组中构成了哮喘的独立因素,类似于特应性和对甜味的感知降低。此外,还试图确定可能的治疗和预防性干预措施,以治疗和预防儿童慢性鼻窦炎的生态失调。
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引用次数: 0
Congenital torticollis in an infant 婴儿先天性斜颈
Q4 PEDIATRICS Pub Date : 2023-08-28 DOI: 10.15557/pimr.2023.0023
Priyantha Pang, Jeyasakthy Saniasiaya, Jeyanthi Kulasegarah
Introduction: Fibromatosis colli is an uncommon congenital infantile tumour occurring in 0.4–1.3% of live births. They are non-malignant, however early detection and treatment are crucial. This is because, if left untreated, fibromatosis colli tumours can cause permanent disfigurements to the skull and spine of the infant. The main aetiology that causes congenital fibromatosis colli is believed to be muscle injury, either intrauterine or during childbirth. A common symptom of congenital fibromatosis colli is head tilting toward the affected side. Case report: This case report discusses the management of an 82-day-old infant with fibromatosis colli. Discussion: Clinical examination including palpation and examination of the range of movement of the sternocleidomastoid muscle is the key to diagnosing fibromatosis colli. Early physiotherapy represents the first-line treatment in affected infants.
大肠纤维瘤病是一种罕见的先天性婴儿肿瘤,发生率为活产婴儿的0.4-1.3%。它们是非恶性的,但早期发现和治疗至关重要。这是因为,如果不及时治疗,纤维瘤病会导致婴儿的头骨和脊柱永久性毁容。引起先天性大肠纤维瘤病的主要病因被认为是子宫内或分娩时的肌肉损伤。先天性结肠纤维瘤病的常见症状是头部向患病一侧倾斜。病例报告:本病例报告讨论了一例82日龄婴儿结肠炎纤维瘤病的处理。讨论:临床检查包括触诊及胸锁乳突肌活动范围检查是诊断大肠纤维瘤病的关键。早期物理治疗是患病婴儿的一线治疗。
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引用次数: 0
House dust mite allergy may increase the severity of chronic rhinosinusitis in preschool and early school-age children 屋尘螨过敏可增加学龄前和学龄早期儿童慢性鼻窦炎的严重程度
Q4 PEDIATRICS Pub Date : 2023-08-28 DOI: 10.15557/pimr.2023.0013
Katarzyna Molińska, Marta Latek, Paweł Majak
Introduction and objective: Chronic rhinosinusitis is often diagnosed in the paediatric population. The pathogenesis of the condition is a complex and not fully understood process involving disorders of the immune system, allergies, and environmental and social aspects. The study aimed to determine the clinical, immunological, and microbiological factors influencing the clinical course of chronic rhinosinusitis in preschool and early school-age children. Materials and methods: This cross-sectional study included one hundred and eleven children aged 4–8 years, with chronic rhinosinusitis diagnosed by otolaryngologists. The following procedures were performed in each patient: a standardised SN-5 (Sinus and Nasal Quality of Life Survey) questionnaire, a questionnaire evaluating the applied treatment, skin prick tests with inhaled allergens, and nasopharyngeal swab for microbiome analysis. Results: The univariate regression analysis found that children who had previously attended nursery, children who were allergic to perennial allergens and house dust mites, and children with atopy, demonstrated more severe symptoms of chronic rhinosinusitis (SN-5 >3.6 pts). The multivariate model confirmed that the only independent factor for a more severe course of chronic rhinosinusitis (odds ratio, OR = 4.1; 95% confidence interval, 95% CI: 1.4–11.9; p = 0.007) was the children’s allergy to house dust mites. Conclusions: House dust mite allergy may increase the severity of chronic rhinosinusitis in young children, which justifies an attempt to implement additional recommendations for the treatment of allergic inflammation.
简介和目的:慢性鼻窦炎常在儿科人群中诊断。该病的发病机制是一个复杂且尚未完全了解的过程,涉及免疫系统、过敏、环境和社会方面的疾病。本研究旨在确定影响学龄前和学龄前儿童慢性鼻窦炎临床病程的临床、免疫学和微生物学因素。材料和方法:这项横断面研究包括111名年龄在4-8岁的儿童,由耳鼻喉科医生诊断为慢性鼻窦炎。对每位患者进行以下程序:标准化的SN-5(鼻窦和鼻腔生活质量调查)问卷,应用治疗评估问卷,吸入过敏原的皮肤点刺试验,鼻咽拭子进行微生物组分析。结果:单因素回归分析发现,曾上过托儿所的儿童、对常年性过敏原和室内尘螨过敏的儿童以及特应性儿童表现出更严重的慢性鼻窦炎症状(SN-5 >3.6 pts)。多变量模型证实,慢性鼻窦炎病程加重的唯一独立因素(优势比,OR = 4.1;95%置信区间,95% CI: 1.4-11.9;P = 0.007)为儿童对屋尘螨的过敏。结论:屋尘螨过敏可能会增加幼儿慢性鼻窦炎的严重程度,这证明了对过敏性炎症治疗实施额外建议的尝试是合理的。
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引用次数: 0
Congenital ureteral valve as a diagnostically challenging congenital ureteral defect 先天性输尿管瓣膜作为先天性输尿管缺损的诊断挑战
Q4 PEDIATRICS Pub Date : 2023-08-28 DOI: 10.15557/pimr.2023.0018
Joanna Cybulska, Beata Jurkiewicz, Joanna Samotyjek
The authors present two cases of ureteral valves. This rare urinary tract defect, causing abnormal urine flow from the upper urinary tract, is usually diagnosed intraoperatively. A 15-year-old girl with renal colic was admitted to hospital. Abdominal ultrasonography showed pelvicalyceal dilation in the right kidney and the X-ray showed a shadow in the orifice of the left ureter. She underwent bilateral ureterorenoscopy. A left ureteral valve was visualised during the examination. A 13-year-old boy was admitted to the Department of Surgery due to pelvicalyceal and left ureteral dilatation. Based on imaging and clinical findings, both patients underwent surgical treatment. Valves were found in the distal part of the left ureters. They were resected and the ureters were transplanted. Histopathological examination showed the presence of smooth muscle in the folds of the valve, confirming the final diagnosis.
作者报告两例输尿管瓣膜。这种罕见的泌尿道缺陷,引起异常尿液从上尿路流出,通常在术中诊断。一名15岁女孩因肾绞痛入院。腹部超声示右肾盆腔扩张,x线示左输尿管口影。她接受了双侧输尿管镜检查。检查时可见左侧输尿管瓣膜。一名13岁男孩因骨盆及左输尿管扩张而住进外科。根据影像学和临床表现,两例患者均接受了手术治疗。左输尿管远端可见瓣膜。他们被切除,输尿管被移植。组织病理学检查显示瓣膜褶皱处有平滑肌,证实了最终的诊断。
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引用次数: 0
Influenza complications among patients attending family practitioner practice 参加家庭医生执业的病人的流感并发症
IF 3.6 Q4 PEDIATRICS Pub Date : 2023-06-30 DOI: 10.15557/pimr.2023.0006
Aneta Elżbieta Rzepka, A. Mania
Introduction: Influenza is an acute viral disease of the respiratory system. Its course can be complicated, particularly in seniors, young children or patients with chronic conditions. Common complications include pneumonia, exacerbation of chronic diseases, heart muscle involvement, and neurologic disorders. This paper analyses the frequency and factors contributing to the development of influenza complications in primary healthcare patients. Materials and methods: The study enrolled a total of 631 adult patients who visited a family physician complaining of respiratory tract infections from January 2019 to April 2020 in the Family Doctor’s Clinic in Gostyń, Greater Poland Province. Of them, 90 patients were diagnosed with influenza. The data sources included patient interviews, physical examinations, results of additional tests, and the patients’ medical files. The diagnosis of influenza was based on the accepted clinical criteria, i.e. a sudden onset of fever + ≥1 clinical symptom in the respiratory system + ≥1 general systemic symptom, lasting <72 hours and confirmed with an Actim Influenza A&B test (Medix Biochemica). Results: Complications of influenza were noted in 13 patients (14%), compared to 77 uncomplicated cases. Four patients required hospital admission. The diagnosed complications included secondary bacterial infection of the lower respiratory tract (61%), exacerbation of chronic diseases (31%), and myocarditis (8%). In logistic regression analysis, asphyxia, wheezing, and crackles were linked to a higher risk of complicated influenza. Conclusions: Complicated influenza occurs significantly more often in patients with multiple comorbidities, including obesity, thyroid diseases, and liver diseases. Clinical symptoms related to the risk of complications include asphyxia, wheezing, and crackles.
简介:流感是一种急性呼吸道病毒性疾病。它的病程可能很复杂,尤其是在老年人、幼儿或慢性病患者中。常见的并发症包括肺炎、慢性病加重、心肌受累和神经系统疾病。本文分析了初级保健患者发生流感并发症的频率和因素。材料和方法:该研究共招募了631名成年患者,他们于2019年1月至2020年4月在大波兰省Gostyń的家庭医生诊所就诊,抱怨呼吸道感染。其中90名患者被诊断为流感。数据来源包括患者访谈、体检、额外检查结果和患者的医疗档案。流感的诊断基于公认的临床标准,即突然发烧+呼吸系统≥1种临床症状+≥1种全身症状,持续时间<72小时,并通过Actim流感a&B测试(Medix Biochemica)确认。结果:13例患者(14%)出现流感并发症,而77例无并发症。四名患者需要住院治疗。诊断的并发症包括下呼吸道继发性细菌感染(61%)、慢性病恶化(31%)和心肌炎(8%)。在逻辑回归分析中,窒息、喘息和爆裂与并发流感的风险较高有关。结论:复杂性流感在患有多种合并症的患者中更常见,包括肥胖、甲状腺疾病和肝病。与并发症风险相关的临床症状包括窒息、喘息和爆裂。
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引用次数: 0
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