Pub Date : 2017-01-01DOI: 10.4172/2324-8599-C1-005
S. Picaud
{"title":"Visual restoration by retinal prostheses and optogenetic therapy: Validation in non-human primates","authors":"S. Picaud","doi":"10.4172/2324-8599-C1-005","DOIUrl":"https://doi.org/10.4172/2324-8599-C1-005","url":null,"abstract":"","PeriodicalId":89944,"journal":{"name":"International Journal of Ophthalmic Pathology","volume":"06 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70883568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-01DOI: 10.4172/2324-8599-C1-002
D. Borchman
{"title":"Whales, lifespan, phospholipids and the cause and cure for cataracts","authors":"D. Borchman","doi":"10.4172/2324-8599-C1-002","DOIUrl":"https://doi.org/10.4172/2324-8599-C1-002","url":null,"abstract":"","PeriodicalId":89944,"journal":{"name":"International Journal of Ophthalmic Pathology","volume":"06 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70883967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-01DOI: 10.4172/2324-8599-C1-001
S. Hamada
{"title":"Ocular surface reconstruction: Current and future","authors":"S. Hamada","doi":"10.4172/2324-8599-C1-001","DOIUrl":"https://doi.org/10.4172/2324-8599-C1-001","url":null,"abstract":"","PeriodicalId":89944,"journal":{"name":"International Journal of Ophthalmic Pathology","volume":"06 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70883792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-01DOI: 10.4172/2324-8599-C1-006
C. A. Mathew
{"title":"A tragic tale of a lost eye an unusual case of endogenous endophthalmitis","authors":"C. A. Mathew","doi":"10.4172/2324-8599-C1-006","DOIUrl":"https://doi.org/10.4172/2324-8599-C1-006","url":null,"abstract":"","PeriodicalId":89944,"journal":{"name":"International Journal of Ophthalmic Pathology","volume":"06 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70883629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-01DOI: 10.4172/2324-8599-C1-003
G. Pires
{"title":"Refractive use of intrastromal rings in keratoplasty","authors":"G. Pires","doi":"10.4172/2324-8599-C1-003","DOIUrl":"https://doi.org/10.4172/2324-8599-C1-003","url":null,"abstract":"","PeriodicalId":89944,"journal":{"name":"International Journal of Ophthalmic Pathology","volume":"06 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70883865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-01DOI: 10.4172/2324-8599-C1-004
K. Daba
{"title":"Bilateral keratomalacia secondary to diet induced vitamin A deficiency in an Ethiopian young woman: A case report","authors":"K. Daba","doi":"10.4172/2324-8599-C1-004","DOIUrl":"https://doi.org/10.4172/2324-8599-C1-004","url":null,"abstract":"","PeriodicalId":89944,"journal":{"name":"International Journal of Ophthalmic Pathology","volume":"06 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70883929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-12-27DOI: 10.4172/2324-8599.1000189
S. Singh, R. Oli, M. Srivastava, Deepika Singh, Jagdish Dukre
Introduction: To establish the strength of the association between routine tear function tests and conjunctival impression cytology (CIC) and to determine whether they simulate the morphological and cytological changes that occur on the ocular surface in dry eye. Materials and Methods: Fifty six patients (30 cases and 26 controls) were included in the study. The tear film profile included tear film break up time (TBUT), Schirmer’s-1, Rose Bengal scores (RBS), and impression cytology. CIC samples were obtained from the infero-temporal quadrant of bulbar conjunctiva and stained with Papanicolaou stain (PAP) and Periodic Acid Schiff (PAS) stains. Results: In our study, among clinical tests RBS (86.7%) had maximum sensitivity and highest percentage of specificity of TBUT (88.5%). Predictive values of Schirmer’s test, RBS, GCD, TBUT and CIC was 77.8%, 83.9%, 87.9%, 88.9% and 93.8% respectively in our study group. Cytological findings correlated well with histological findings. Conclusion: Impression cytology was found to be better when compared to clinical tests. These etiopathological findings will help to decide proper line of management.
{"title":"Clinicopathological Correlation in Dry Eye Disease","authors":"S. Singh, R. Oli, M. Srivastava, Deepika Singh, Jagdish Dukre","doi":"10.4172/2324-8599.1000189","DOIUrl":"https://doi.org/10.4172/2324-8599.1000189","url":null,"abstract":"Introduction: To establish the strength of the association between routine tear function tests and conjunctival impression cytology (CIC) and to determine whether they simulate the morphological and cytological changes that occur on the ocular surface in dry eye. \u0000Materials and Methods: Fifty six patients (30 cases and 26 controls) were included in the study. The tear film profile included tear film break up time (TBUT), Schirmer’s-1, Rose Bengal scores (RBS), and impression cytology. CIC samples were obtained from the infero-temporal quadrant of bulbar conjunctiva and stained with Papanicolaou stain (PAP) and Periodic Acid Schiff (PAS) stains. \u0000Results: In our study, among clinical tests RBS (86.7%) had maximum sensitivity and highest percentage of specificity of TBUT (88.5%). Predictive values of Schirmer’s test, RBS, GCD, TBUT and CIC was 77.8%, 83.9%, 87.9%, 88.9% and 93.8% respectively in our study group. Cytological findings correlated well with histological findings. \u0000Conclusion: Impression cytology was found to be better when compared to clinical tests. These etiopathological findings will help to decide proper line of management.","PeriodicalId":89944,"journal":{"name":"International Journal of Ophthalmic Pathology","volume":"2016 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2016-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70883019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-12-27DOI: 10.4172/2324-8599.1000191
M. García-Zamora, H. Sánchez-Tocino, José Miguel Angles-Deza, L. Sánchez-Velicia, E. García-Zamora
A 32 weeks gestational aged male infant, with eyelid edema and severe ptosis presented on 7th day after birth, was admitted into Pediatric department and treated as periorbital cellulitis. The response with conventional antibiotics was not effective and the eyelid edema persisted, appearing an Eyelid Edema as a First Presentation of Cutaneous Mastocytosis.
{"title":"Eyelid Edema as a First Presentation of Cutaneous Mastocytosis","authors":"M. García-Zamora, H. Sánchez-Tocino, José Miguel Angles-Deza, L. Sánchez-Velicia, E. García-Zamora","doi":"10.4172/2324-8599.1000191","DOIUrl":"https://doi.org/10.4172/2324-8599.1000191","url":null,"abstract":"A 32 weeks gestational aged male infant, with eyelid edema and severe ptosis presented on 7th day after birth, was admitted into Pediatric department and treated as periorbital cellulitis. The response with conventional antibiotics was not effective and the eyelid edema persisted, appearing an Eyelid Edema as a First Presentation of Cutaneous Mastocytosis.","PeriodicalId":89944,"journal":{"name":"International Journal of Ophthalmic Pathology","volume":"2016 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2016-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70883084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: To investigate the clinically estimated incidence and risk factors for age-related macular degeneration (AMD) in a various nationalities in Tibet and Qinghai plateau. Methods: 185 AMD patients (288 eyes), aged 40 to 86 years and lived in Qinghai-Tibet plateau area (with a sea-level of 1800 m - 4300 m), were enrolled. All patients were assigned into four groups based on their nationalities. The Detached Angiography, Optical Coherence Tomography (OCT), Fundus Photography, Visual Acuity, Slit-Lamp Examination, Intraocular Pressure, Laboratory Blood Test were employed. Results: The data showed that the Qinghai region’s AMD patients in the 70 year old group are 43.25%, accounting for the largest proportion, while the 40 age group is 10.27%. AMD is significantly more prevalent in men than in women. In our 185 cases, the number of binocular cases is higher than that of the monocular. Dry AMD (56.25%) is higher than wet (43.75%). Blind and low vision patients constitute 9.03% and 28.47%, respectively. Vision loss in Tibetan patients is much higher than in Han patients (40.5% vs 28.6%). In the four different concentrations of hemoglobin, the 180 g/L group of AMD patients occupied 83 cases (44.86%). The vision damage is much more serious in exudative SMD than atrophic SMD determined by Fundus fluorescence angiography (FFA). The blood tests showed higher levels of triglycerides, red blood cells deposit, blood sugar, uric acid, and low density lipoprotein cholesterol (LDL-C) but lower levels of high density lipoprotein (HDL-C). Risk factors related to the plateau AMD may include: smoking, angiocardiopathy, hypertension, chronic obstructive pulmonary disease, and diabetes. Conclusion: The chronic hypoxia environment may contribute to systemic changes of the body including retinal macular degeneration. Age, sex, smoking, particularly angiocardiopathy may be the main risk factors associated with AMD in the Qinghai-Tibetan Plateau.
目的:探讨青藏高原各民族老年性黄斑变性(AMD)的临床估计发病率及危险因素。方法:选取生活在青藏高原地区(海拔1800 ~ 4300米)，年龄40 ~ 86岁的黄斑变性患者185例(288眼)。所有患者根据国籍分为四组。采用离体血管造影、光学相干断层扫描(OCT)、眼底摄影、视力、裂隙灯检查、眼压、血检。结果:数据显示，青海地区70岁年龄组AMD患者占43.25%，占比最大，40岁年龄组占10.27%。AMD在男性中的发病率明显高于女性。在我们的185例病例中，双眼病例数高于单眼病例数。干性AMD(56.25%)高于湿性AMD(43.75%)。失明和低视力患者分别占9.03%和28.47%。藏族患者的视力下降明显高于汉族患者(40.5% vs 28.6%)。在4种不同血红蛋白浓度中，180 g/L组AMD患者占83例(44.86%)。眼底荧光血管造影(FFA)显示渗出性SMD的视力损害比萎缩性SMD严重得多。血液检查显示甘油三酯、红细胞沉积、血糖、尿酸和低密度脂蛋白胆固醇(LDL-C)水平较高，但高密度脂蛋白(HDL-C)水平较低。与平台型AMD相关的危险因素可能包括:吸烟、心血管疾病、高血压、慢性阻塞性肺疾病和糖尿病。结论:慢性缺氧环境可引起包括视网膜黄斑变性在内的全身病变。年龄、性别、吸烟，尤其是心血管疾病可能是青藏高原AMD发病的主要危险因素。
{"title":"A Clinical Analysis of Age-Related Macular Degeneration in Qinghai Plateau","authors":"Aiqin Zhu, Lingyi Li, X. Zhong, Guofeng Li, Yin-long Li, Xiangxing Guo, Junming Lou, Zhen-Shen Qing, Shengzheng Wu, Jun Zhang","doi":"10.4172/2324-8599.1000179","DOIUrl":"https://doi.org/10.4172/2324-8599.1000179","url":null,"abstract":"Aim: To investigate the clinically estimated incidence and risk factors for age-related macular degeneration (AMD) in a various nationalities in Tibet and Qinghai plateau. \u0000Methods: 185 AMD patients (288 eyes), aged 40 to 86 years and lived in Qinghai-Tibet plateau area (with a sea-level of 1800 m - 4300 m), were enrolled. All patients were assigned into four groups based on their nationalities. The Detached Angiography, Optical Coherence Tomography (OCT), Fundus Photography, Visual Acuity, Slit-Lamp Examination, Intraocular Pressure, Laboratory Blood Test were employed. \u0000Results: The data showed that the Qinghai region’s AMD patients in the 70 year old group are 43.25%, accounting for the largest proportion, while the 40 age group is 10.27%. AMD is significantly more prevalent in men than in women. In our 185 cases, the number of binocular cases is higher than that of the monocular. Dry AMD (56.25%) is higher than wet (43.75%). Blind and low vision patients constitute 9.03% and 28.47%, respectively. Vision loss in Tibetan patients is much higher than in Han patients (40.5% vs 28.6%). In the four different concentrations of hemoglobin, the 180 g/L group of AMD patients occupied 83 cases (44.86%). The vision damage is much more serious in exudative SMD than atrophic SMD determined by Fundus fluorescence angiography (FFA). The blood tests showed higher levels of triglycerides, red blood cells deposit, blood sugar, uric acid, and low density lipoprotein cholesterol (LDL-C) but lower levels of high density lipoprotein (HDL-C). Risk factors related to the plateau AMD may include: smoking, angiocardiopathy, hypertension, chronic obstructive pulmonary disease, and diabetes. \u0000Conclusion: The chronic hypoxia environment may contribute to systemic changes of the body including retinal macular degeneration. Age, sex, smoking, particularly angiocardiopathy may be the main risk factors associated with AMD in the Qinghai-Tibetan Plateau.","PeriodicalId":89944,"journal":{"name":"International Journal of Ophthalmic Pathology","volume":"2016 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2016-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70882236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-12-05DOI: 10.4172/2324-8599.1000180
H. Chung, Steve Rasmussen, D. Rossman
Pleomorphic adenomas (PA) are common benign tumours of the lacrimal gland. Necrosis in PA is unusual and should raise a suspicion and screen for malignancy. We hereby present a case report of pleomorphic adenoma with necrotic foci in the orbit of a 44-year-old lady and a review of current literature for focal necrosis in orbital pleomorphic adenoma.
{"title":"Focal Necrosis in Orbital Pleomorphic Adenoma","authors":"H. Chung, Steve Rasmussen, D. Rossman","doi":"10.4172/2324-8599.1000180","DOIUrl":"https://doi.org/10.4172/2324-8599.1000180","url":null,"abstract":"Pleomorphic adenomas (PA) are common benign tumours of the lacrimal gland. Necrosis in PA is unusual and should raise a suspicion and screen for malignancy. We hereby present a case report of pleomorphic adenoma with necrotic foci in the orbit of a 44-year-old lady and a review of current literature for focal necrosis in orbital pleomorphic adenoma.","PeriodicalId":89944,"journal":{"name":"International Journal of Ophthalmic Pathology","volume":"2016 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2016-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70882295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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