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Does Acellular Dermal Matrix Thickness Affect Complication Rate in Tissue Expander Based Breast Reconstruction? 脱细胞真皮基质厚度是否影响组织扩张器乳房重建的并发症发生率?
Pub Date : 2016-01-01 Epub Date: 2016-04-12 DOI: 10.1155/2016/2867097
Jessica F Rose, Sarosh N Zafar, Warren A Ellsworth Iv

Background. While the benefits of using acellular dermal matrices (ADMs) in breast reconstruction are well described, their use has been associated with additional complications. The purpose of this study was to determine if ADM thickness affects complications in breast reconstruction. Methods. A retrospective chart review was performed including all tissue expander based breast reconstructions with AlloDerm (LifeCell, Branchburg, NJ) over 4 years. We evaluated preoperative characteristics and assessed postoperative complications including seroma, hematoma, infection, skin necrosis, and need for reintervention. We reviewed ADM thickness and time to Jackson-Pratt (JP) drain removal. Results. Fifty-five patients underwent 77 ADM-associated tissue expander based breast reconstructions, with average age of 48.1 years and average BMI of 25.9. Average ADM thickness was 1.21 mm. We found higher complication rates in the thick ADM group. Significant associations were found between smokers and skin necrosis (p < 0.0001) and seroma and prolonged JP drainage (p = 0.0004); radiated reconstructed breasts were more likely to suffer infections (p = 0.0085), and elevated BMI is a significant predictor for increased infection rate (p = 0.0037). Conclusion. We found a trend toward increased complication rates with thicker ADMs. In the future, larger prospective studies evaluating thickness may provide more information.

背景。虽然在乳房重建中使用脱细胞真皮基质(ADMs)的好处已经得到了很好的描述,但它们的使用与其他并发症有关。本研究的目的是确定ADM的厚度是否影响乳房重建的并发症。方法。对所有使用AlloDerm (LifeCell, Branchburg, NJ)进行的基于组织扩张器的乳房重建进行回顾性图表回顾,时间超过4年。我们评估了术前特征和术后并发症,包括血肿、血肿、感染、皮肤坏死和再次干预的需要。我们回顾了ADM的厚度和去除杰克逊-普拉特(JP)排水管的时间。结果。55例患者接受了77例adm相关组织扩张器乳房重建,平均年龄为48.1岁,平均BMI为25.9。平均ADM厚度1.21 mm。我们发现厚ADM组的并发症发生率更高。吸烟者与皮肤坏死(p < 0.0001)、血清肿和JP引流延长(p = 0.0004)有显著相关性;放射重建乳房更容易发生感染(p = 0.0085), BMI升高是感染率增加的重要预测因子(p = 0.0037)。结论。我们发现,较厚的adm有增加并发症发生率的趋势。在未来,更大的评估厚度的前瞻性研究可能会提供更多的信息。
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引用次数: 21
Nose and Midface Augmentation by Rib Cartilage Grafts: Methods and Outcome in 32 Cases 肋软骨隆鼻术32例疗效观察
Pub Date : 2015-12-10 DOI: 10.1155/2015/849802
A. Farouk, S. Ibrahiem
Recession of the midface is a relatively common condition that can have a negative impact on facial and nasal aesthetic appearance, and it poses a challenge to plastic surgeons. In cases with generalized maxillary retrusion and/or malocclusion, bone advancement surgery is required, but in localized cases, mostly seen in cleft lip patients, the quest is for an ideal material and a proper technique that would be used to augment the receding area. Throughout a period of seven years, thirty-two patients with nose and midface retrusion were managed by a construct of rib cartilage grafts designed to compensate the deficiency at the maxillary, piriform, and premaxillary areas. Results were satisfactory for most patients in terms of improved fullness of malar area, improved nasal tip projection and rotation, and improvement of upper lip. The presented technique of rib cartilage grafting is a safe and effective method for nose and midface augmentation.
中脸凹陷是一种相对常见的情况,它会对面部和鼻子的美观产生负面影响,这对整形外科医生提出了挑战。在全身性上颌后缩和/或错颌的病例中,需要进行骨推进手术,但在局部病例中,主要见于唇裂患者,需要寻找理想的材料和适当的技术来增加后退区域。在7年的时间里,32例鼻和中脸后缩患者通过肋骨软骨移植来弥补上颌、梨状和上颌前区域的缺陷。大多数患者在改善颧区丰满度,改善鼻尖突出和旋转以及改善上唇方面的结果令人满意。肋软骨移植术是一种安全、有效的鼻、中脸隆胸方法。
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引用次数: 3
Stem Cell-Based Therapeutics to Improve Wound Healing 干细胞疗法改善伤口愈合
Pub Date : 2015-11-15 DOI: 10.1155/2015/383581
Michael S. Hu, Tripp Leavitt, Samir Malhotra, D. Duscher, Michael S. Pollhammer, G. Walmsley, Z. Maan, Alexander T. M. Cheung, Manfred Schmidt, G. Huemer, M. Longaker, H. Lorenz
Issues surrounding wound healing have garnered deep scientific interest as well as booming financial markets invested in novel wound therapies. Much progress has been made in the field, but it is unsurprising to find that recent successes reveal new challenges to be addressed. With regard to wound healing, large tissue deficits, recalcitrant wounds, and pathological scar formation remain but a few of our most pressing challenges. Stem cell-based therapies have been heralded as a promising means by which to surpass current limitations in wound management. The wide differentiation potential of stem cells allows for the possibility of restoring lost or damaged tissue, while their ability to immunomodulate the wound bed from afar suggests that their clinical applications need not be restricted to direct tissue formation. The clinical utility of stem cells has been demonstrated across dozens of clinical trials in chronic wound therapy, but there is hope that other aspects of wound care will inherit similar benefit. Scientific inquiry into stem cell-based wound therapy abounds in research labs around the world. While their clinical applications remain in their infancy, the heavy investment in their potential makes it a worthwhile subject to review for plastic surgeons, in terms of both their current and future applications.
围绕伤口愈合的问题已经获得了深刻的科学兴趣,以及蓬勃发展的金融市场对新型伤口疗法的投资。这一领域已经取得了很大进展,但最近的成功揭示了有待解决的新挑战,这并不令人惊讶。关于伤口愈合,大组织缺损,顽固性伤口和病理性瘢痕形成仍然是我们最紧迫的挑战。干细胞疗法被认为是一种很有前途的方法,可以超越目前伤口管理的局限性。干细胞的广泛分化潜力允许恢复丢失或受损组织的可能性,而它们从远处免疫调节伤口床的能力表明它们的临床应用不需要局限于直接组织形成。干细胞的临床应用已经在数十个慢性伤口治疗的临床试验中得到证实,但伤口护理的其他方面也有希望继承类似的益处。在世界各地的研究实验室中,对干细胞伤口治疗的科学研究比比皆是。虽然它们的临床应用仍处于起步阶段,但对其潜力的大量投资使其成为整形外科医生在当前和未来应用方面值得审查的主题。
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引用次数: 40
Use of Lateral Calcaneal Flap for Coverage of Hindfoot Defects: An Anatomical Appraisal 使用外侧跟骨瓣覆盖后足缺损:解剖学评价
Pub Date : 2015-11-11 DOI: 10.1155/2015/212757
Panagiotis Zygouris, A. Michalinos, V. Protogerou, E. Kotsiomitis, A. Mazarakis, I. Dimovelis, T. Troupis
Lateral calcaneal flap is an established surgical option for coverage of lateral calcaneum and posterior heel defects. Lateral calcaneal flap vascularization and innervations are based on lateral calcaneal artery neurovascular bundle, that is, lateral calcaneal artery, small saphenous vein, and sural nerve. Anatomical research has allowed exploration of its many advantages but can also lead to its various modifications, permitting a wide variety of clinical applications. In this paper the authors report an anatomical and clinical study on lateral calcaneal artery course and lateral calcaneal flap clinical applications. Anatomic part of our study focused on lateral calcaneal artery course and optimization of surgical technique for flap harvesting. Data were used for design of lateral calcaneal flap in 5 patients. Our results were satisfactory in terms of coverage adequacy, perioperative morbidity, and functional and aesthetical outcome.
外侧跟骨瓣是修复外侧跟骨和后跟缺损的常用手术方法。跟外侧皮瓣血管化和神经支配以跟外侧动脉神经维管束为主,即跟外侧动脉、小隐静脉、腓肠神经为主。解剖研究已经允许探索其许多优点,但也可以导致其各种修改,允许各种临床应用。本文对跟外侧动脉走行及跟外侧皮瓣的临床应用进行了解剖学和临床研究。解剖部分我们的研究集中在跟外侧动脉的路线和手术技术的优化皮瓣收获。利用数据设计5例跟外侧皮瓣。我们的结果在覆盖充分性、围手术期发病率、功能和美观结果方面令人满意。
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引用次数: 2
Mandibular Ramus Fracture: An Overview of Rare Anatomical Subsite 下颌支骨折:罕见解剖亚区综述
Pub Date : 2015-11-03 DOI: 10.1155/2015/954314
Anendd Jadhav, Bhushan P Mundada, Rahul V. Deshmukh, Umesh Bhutekar, A. Kala, Kapil Waghwani, Apoorva Mishra
Aim. The present study aims at exemplifying the incidence, and aetiology and analyses the outcomes of open reduction internal fixation (ORIF) over closed treatment of mandibular ramus fractures. Patients and Method. In the present retrospective analysis of mandibular fracture patients, variables analysed were age, sex, cause of injury, pretreatment occlusion, treatment given, period of maxillo-mandibular fixation (MMF), and posttreatment occlusion. Results. Out of 388 mandibular fractures treated, ramus fractures were 12 (3.09%). In the present study, predominant cause of mandibular ramus fracture was road traffic accident (RTA) n = 07 (58.33%) followed by fall n = 04 (33.33%) and assault n = 1 (8.33%). The average age was 35.9 years with a male predilection. Of these, 9 patients were treated with ORIF while remaining 3 with closed treatment. The average MMF after closed treatment was 21 days and 3 to 5 days after ORIF. There was improvement in occlusion in all 12 patients posttreatment with no major complication except for reduced mouth opening in cases treated with ORIF which recovered with physiotherapy and muscle relaxants. Conclusion. Mandibular ramus fractures accounted for 3.09% with RTA as a common aetiology. ORIF of ramus fractures facilitated adequate functional and anatomic reduction with early return of function.
的目标。本研究旨在举例说明发生率和病因,并分析开放复位内固定(ORIF)治疗下颌支骨折的效果。患者和方法。在本次对下颌骨折患者的回顾性分析中,分析的变量包括年龄、性别、损伤原因、预处理咬合、治疗方法、上颌-下颌固定(MMF)时间和治疗后咬合。结果。治疗的388例下颌骨骨折中,支骨折12例(3.09%)。在本研究中,导致下颌支骨折的主要原因是道路交通事故(RTA) n = 07(58.33%),其次是跌倒n = 04(33.33%)和殴打n = 1(8.33%)。平均年龄为35.9岁,以男性为主。其中9例患者接受ORIF治疗,其余3例患者接受封闭治疗。封闭治疗后平均MMF为21天,ORIF后平均MMF为3 ~ 5天。所有12例患者治疗后咬合均有改善,除经ORIF治疗的患者经物理治疗和肌肉松弛剂恢复后开口减小外,无主要并发症。结论。下颌支骨折占3.09%,RTA是常见的病因。支骨折的ORIF促进了足够的功能和解剖复位和早期功能恢复。
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引用次数: 19
Telemedicine and Plastic Surgery: A Pilot Study 远程医疗和整形外科:一项试点研究
Pub Date : 2015-11-02 DOI: 10.1155/2015/187505
D. S. Valente, Luciano Silveira Eifler, L. A. Carvalho, G. P. Filho, Vinicius Weissheimer Ribeiro, A. Padoin
Background. Telemedicine can be defined as the use of electronic media for transmission of information and medical data from one site to another. The objective of this study is to demonstrate an experience of telemedicine in plastic surgery. Methods. 32 plastic surgeons received a link with password for real-time streaming of a surgery. At the end of the procedure, the surgeons attending the procedure by the Internet answered five questions. The results were analyzed with descriptive statistics. Results. 27 plastic surgeons attended the online procedure in real-time. 96.3% considered the access to the website as good or excellent and 3.7% considered it bad. 14.8% reported that the transmission was bad and 85.2% considered the quality of transmission as good or excellent. 96.3% classified the live broadcasting as a good or excellent learning experience and 3.7% considered it a bad experience. 92.6% reported feeling able to perform this surgery after watching the demo and 7.4% did not feel able. 100% of participants said they would like to participate in other surgical demonstrations over the Internet. Conclusion. We conclude that the use of telemedicine can provide more access to education and medical research, for plastic surgeons looking for medical education from distant regions.
背景。远程医疗可以定义为利用电子媒体将信息和医疗数据从一个地点传输到另一个地点。本研究的目的是展示远程医疗在整形外科的经验。方法:32名整形外科医生收到一个带有密码的链接,用于实时流媒体手术。手术结束后,参加手术的外科医生通过互联网回答了五个问题。结果用描述性统计进行分析。结果:27名整形外科医生实时参加了在线手术。96.3%的人认为网站的访问良好或非常好,3.7%的人认为很差。14.8%的人认为传播不良,85.2%的人认为传播质量良好或优秀。96.3%的人认为直播是一个好的或非常好的学习经历,3.7%的人认为直播是一个糟糕的经历。92.6%的人在看完演示后感觉可以进行手术,7.4%的人不觉得可以。100%的参与者表示他们愿意在互联网上参加其他手术演示。结论。我们的结论是,远程医疗的使用可以为从遥远地区寻求医学教育的整形外科医生提供更多的教育和医学研究机会。
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引用次数: 15
Sociodemographic Predictors of Breast Reconstruction Procedure Choice: Analysis of the Mastectomy Reconstruction Outcomes Consortium Study Cohort 乳房重建手术选择的社会人口学预测因素:乳房切除术重建结果联合研究队列分析
Pub Date : 2015-10-29 DOI: 10.1155/2015/150856
Tiffany N. S. Ballard, Yeonil Kim, Wess A. Cohen, J. Hamill, Adeyiza O. Momoh, A. Pusic, H. Myra Kim, E. Wilkins
Background. To promote patient-centered care, it is important to understand the impact of sociodemographic factors on procedure choice for women undergoing postmastectomy breast reconstruction. In this context, we analyzed the effects of these variables on the reconstructive method chosen. Methods. Women undergoing postmastectomy breast reconstruction were recruited for the prospective Mastectomy Reconstruction Outcomes Consortium Study. Procedure types were divided into tissue expander-implant/direct-to-implant and abdominally based flap reconstructions. Adjusted odds ratios were calculated from logistic regression. Results. The analysis included 2,203 women with current or previous breast cancer and 202 women undergoing prophylactic mastectomy. Compared with women <40 years old with current or previous breast cancer, those 40 to 59 were significantly more likely to undergo an abdominally based flap. Women working or attending school full-time were more likely to receive an autologous procedure than those working part-time or volunteering. Women undergoing prophylactic mastectomy who were ≥50 years were more likely to undergo an abdominal flap compared to those <40. Conclusions. Our results indicate that sociodemographic factors affect the reconstructive procedure received. As we move forward into a new era of patient-centered care, providing tailored treatment options to reconstruction patients will likely lead to higher satisfaction and better outcomes for those we serve.
背景。为了促进以患者为中心的护理,了解社会人口因素对乳房切除术后乳房重建妇女手术选择的影响是很重要的。在这种情况下,我们分析了这些变量对所选择的重建方法的影响。方法。接受乳房切除术后乳房重建的妇女被纳入前瞻性乳房切除术重建结果联合研究。手术类型分为组织扩张器-种植体/直接种植体和腹部皮瓣重建。调整后的优势比通过逻辑回归计算。结果。该分析包括2203名目前或以前患有乳腺癌的妇女和202名接受预防性乳房切除术的妇女。与40岁以下患有乳腺癌或既往患有乳腺癌的女性相比,40岁至59岁的女性更有可能接受腹部皮瓣手术。全职工作或全职上学的妇女比兼职或志愿工作的妇女更有可能接受自体手术。年龄≥50岁接受预防性乳房切除术的妇女比年龄<40岁的妇女更有可能接受腹部皮瓣切除术。结论。我们的研究结果表明,社会人口因素会影响接受的重建手术。随着我们进入以患者为中心的护理新时代,为重建患者提供量身定制的治疗方案可能会给我们所服务的患者带来更高的满意度和更好的结果。
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引用次数: 9
Free flap transfer to preserve main arterial flow in early reconstruction of open fracture in the lower extremity. 自由皮瓣转移在下肢开放性骨折早期重建中保留主动脉血流。
Pub Date : 2015-01-01 Epub Date: 2015-03-12 DOI: 10.1155/2015/213892
Mitsuru Nemoto, Shinsuke Ishikawa, Natsuko Kounoike, Takayuki Sugimoto, Akira Takeda

The selection of recipient vessels is crucial when reconstructing traumatized lower extremities using a free flap. When the dorsalis pedis artery and/or posterior tibial artery cannot be palpated, we utilize computed tomography angiography to verify the site of vascular injury prior to performing free flap transfer. For vascular anastomosis, we fundamentally perform end-to-side anastomosis or flow-through anastomosis to preserve the main arterial flow. In addition, in open fracture of the lower extremity, we utilize the anterolateral thigh flap for moderate soft tissue defects and the latissimus dorsi musculocutaneous flap for extensive soft tissue defects. The free flaps used in these two techniques are long and include a large-caliber pedicle, and reconstruction can be performed with either the anterior or posterior tibial artery. The preparation of recipient vessels is easier during the acute phase early after injury, when there is no influence of scarring. A free flap allows flow-through anastomosis and is thus optimal for open fracture of the lower extremity that requires simultaneous reconstruction of main vessel injury and soft tissue defect from the middle to distal thirds of the lower extremity.

当使用游离皮瓣重建创伤性下肢时,受体血管的选择是至关重要的。当不能触诊足背动脉和/或胫后动脉时,我们在进行游离皮瓣转移之前使用计算机断层血管造影来验证血管损伤的位置。对于血管吻合,我们基本上是端侧吻合或血流吻合,以保持主动脉血流。此外,在下肢开放性骨折中,我们应用股前外侧皮瓣修复中度软组织缺损,应用背阔肌皮瓣修复大面积软组织缺损。在这两种技术中使用的游离皮瓣都很长,包括一个大口径的蒂,重建可以用胫骨前动脉或后动脉进行。在损伤后早期的急性期,没有瘢痕形成的影响,受体血管的制备比较容易。自由皮瓣允许血流吻合,因此对于需要同时重建下肢中部至远端三分之一的主血管损伤和软组织缺损的下肢开放性骨折是最佳选择。
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引用次数: 11
The versatility of autologous fat transplantation in correction of facial deformities: a single-center experience. 自体脂肪移植在面部畸形矫正中的多功能性:单中心经验。
Pub Date : 2015-01-01 Epub Date: 2015-03-03 DOI: 10.1155/2015/703535
Niels Hammer-Hansen, Javed Akram, Tine Engberg Damsgaard

Deformities in the craniofacial region are of great social and functional importance. Several surgical techniques have been used to treat such pathologies often with high morbidity and lacking the ability to address smaller contour defects. The minimally invasive technique of fat transplantation has evolved rapidly within the last few decades. The objective of this paper is to present the versatility and applicability of fat transplantation in a wide range of contour deformities in the craniofacial region. We share our experiences in treating 13 patients with autoimmune disorders, congenital malformations, and acquired defects. Future perspectives of fat transplantation in the field of craniofacial reconstruction are discussed.

颅面畸形具有重要的社会意义和功能意义。几种外科技术已被用于治疗这种疾病,通常具有高发病率和缺乏解决较小轮廓缺陷的能力。在过去的几十年里,微创脂肪移植技术发展迅速。本文的目的是展示脂肪移植在颅面区域广泛轮廓畸形中的多功能性和适用性。我们分享我们治疗自身免疫性疾病,先天性畸形和获得性缺陷的13例患者的经验。讨论了脂肪移植在颅面重建领域的应用前景。
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引用次数: 13
Analysis of Complications in Postbariatric Abdominoplasty: Our Experience. 肥胖后腹部成形术并发症分析:我们的经验。
Pub Date : 2015-01-01 Epub Date: 2015-07-12 DOI: 10.1155/2015/209173
Michele Grieco, Eugenio Grignaffini, Francesco Simonacci, Edoardo Raposio

Abdominoplasty is one of the most popular body-contouring procedures. It is associated with a significant number of complications: the most common ones are seroma, hematoma, infection, wound-healing problems, and skin flap necrosis. From January 2012 to December 2014, 25 patients (18 women and 7 men) (mean age: 51 years) underwent abdominoplastic surgery at the Plastic Surgery Section, Department of Surgical Sciences, University of Parma, Italy. All patients reported a weight loss between 15 kg and 47 kg. All of the of 25 patients were included in the study; minor and major complications were seen in 17 (68%) and 8 (32%) patients, respectively. The percentage of complications in our patients was as follows: 9 patients with seroma (36%); 4 patients with wound dehiscence with delayed wound healing (16%); 3 cases with hematoma (12%); 2 patients with postoperative bleeding (8%); 1 patient (4%) with an umbilical necrosis; 1 patient (4%) with a deep vein thrombosis; 3 patients with infected seroma (12%); and 2 patients with wound infection (8%). There were no cases of postoperative mortality. The aim of this study is to analyze our complications in postbariatric abdominoplasty.

腹部成形术是最流行的身体轮廓手术之一。它与许多并发症相关:最常见的是血肿、血肿、感染、伤口愈合问题和皮瓣坏死。2012年1月至2014年12月在意大利帕尔马大学外科科学系整形外科接受腹部整形手术25例(女18例,男7例),平均年龄51岁。所有患者均报告体重减轻15公斤至47公斤。25例患者全部纳入研究;轻微并发症17例(68%),严重并发症8例(32%)。本组患者出现并发症的比例如下:血清肿9例(36%);创面裂开伴创面延迟愈合4例(16%);血肿3例(12%);术后出血2例(8%);1例(4%)脐带坏死;1例(4%)深静脉血栓形成;感染血肿3例(12%);伤口感染2例(8%)。无术后死亡病例。本研究的目的是分析肥胖后腹部成形术的并发症。
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引用次数: 33
期刊
Plastic Surgery International
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