L'Ateneo parmense. Acta bio-medica : organo della Societa di medicina e scienze naturali di Parma最新文献

The correlation between dopamine-serotonin systems and sexual behaviour and the influence of these two amines on GH secretion is well known. We evaluated GH responses (maximum increase (delta) after OGTT and mean increase (delta M) after insulin test) in a group of 32 males suffering from erective impotence with impotence with abnormal reaction to a glucose tolerance test. Results were compared with those obtained in a group of 13 normal controls. No significant difference in basal values and dynamic responses between the two groups was present. Our data suggest that GH doesn't decrease the tolerance to glucose in these patients. The abnormal values observed during a glucose tolerance test may be due to some agent involved in the interactions between limbic system, ventral lateral and ventral medial hypothalamic nuclei and dopamine-serotonin systems. No influence by this system on GH secretion is evident.

We report about a new angiographic technique, spinal angiography, its indications and complication. Spinal angiography is clearly essential for the diagnosis in retro or intramedullary arterio-venous malformations and for metameric angiomatosis with neurological involvement.

After an experiment comparative clinical study, the authors could point out that biohumoral, semeiological and histopathological alterations in alcoholic hepatopaties, can retrograde only by the suspending the pathogenic alcoholic noxa, and that the improvement can be accelerated by a contemporary administration of a. cycloxilic, thiazolidine carboxylic of argynin, EPL: all antisteatosis substances helping the oxidation of alcohol and fat acids, potentiating the rigeneration of the hepatocyte and resolving the hepatosecretory function alterated.

Stated that official data by large under-report the prevalence of the sexually transmitted diseases a survey questionnaire was mailed to every physician of the district of Parma. The results and the pros and cons of the method are discussed.

A case of Pancoast's syndrome is reported, where subclavian arteriography was the only useful diagnostic procedure to make a diagnosis possible. Utilization and meaning of such a diagnostic technique is discussed, since the typical radiological picture of the syndrome may be lacking, especially in the early stage of the disease. Subclavian arteriography explores th costal-pleuro-vertebral space selectively, being aimed to one of the anatomical structure, the mechanical engagement of which is responsible of the syndrome. Such a technique is advisable even in cases where the Pancoast's syndrome is sustained by an infrequent aetiology, such as metastases.

Chloroquine retinopathy is a drug disease that can be prevented. Among some suggested methods, fluorescence electroretinography allows an evaluation of drug retinal deposit. In fact if a fluorescent substance accumulates in the retinal cells, a very short wavelength stimulus can produce a bioelectric response. If soon detected drug absorption is reversible. Only in a long run, the drug can induce irreversible damages. Thus the importance of continuous control of the patients in treatment with chloroquine-drugs is necessary. In this study the results of an investigation of 38 patients treated with synthetic anit-malarial drugs are shown. In some subjects the presence of the drug in the retina, without anatomic lesions, was demonstrated. These deposits disappeared upon cessation of the treatment. Deposits with or without retinal lesions were noticed in 31% of the observed subjects. In these patients the suspension of drug administration reduced accumulation but did not influence retinal lesion shown by fluorangiography. The authors hypothesized that fluorescent substance deposit is made easier by retinal vasculopathy due to connective tissue disorders.

Békésy audiometry was utilized to show that an abnormal separation of forward and reverse frequency tracing is to be referred to an abnormal fatigability in neurosensorial hearing loss (presbycusis and noise-induced hearing loss). The ascending and descending threshold with continuous tone was compared to fixed frequency per-stimulatory threshold that has been determinated using interrupted and continuous tone. During the study has been evaluated the gap between the continuous and interrupted tone and the excursion amplitude in interrupted and continuous tone. The results are than an abnormal separation between forward and reverse frequency tracings is connected to an abnormal fatigability. Thus, according to other authors, forward-backward Békésy audiometry can be used to show a retrocochlear pathology in the considered hearing loss.

Ultrastructural findings in epithelium of human entero-urinary grafts are presented, five and ten years after intervention. Severity of changes seems to be in relationship with functional defects of grafts, chiefly as voiding is concerned, more than with the duration of implantation and the presence of a sphincteric control. As a matter of fact, as far as an active, regular, complete voiding is obtained, only slight late changes occur in ultrastructure, while flattening of macrovilli and cohalescence of cryptae are early findings. Anyhow, no favorable effect is to be expected from these epithelial changes in order to prevent absorption and/or secretion.

The Authors have studied in retrospect the cardiotocographic registrations of women who had given birth to foetus affected by congenital cardiac disease. The observations of several authors (Heinriche Seideschnur; Fischer) are confirmed that persistent bradycardia in pregnancy or in labour could be a sign of a congenital cardiac anomaly. Furthermore, the high incidence of C.T.G. alterations are noticed (in the form of decelerations and significant reduction of the oscillation amplitudes) in the registrations of foetus affected by such cardiac disease.

An uro-dynamic evaluation has been performed on 25 patients, who had been submitted to abdomino-perineal amputation of the rectum and had thereafter shown functional disturbances of micturition. On the latter, causes and mechanisms are discussed, particularly neurological as well as mechanical and inflammatory ones, with regard to their relationship with sex and other possible aspects in the field of pathology. In 16 cases urinary retention developed, in 4 cases urinary incontinence, in 4 cases urgency but complete voiding. The authors conclude by stressing the role of pre-operative uro-dynamic assessment in every patient who is going to be submitted to rectal exeresis, in order to detect sub-clinical functional impairment of micturition, which could be suitably treated, during the main operation itself, by either desobstructive or reconstructive measures.