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Application Status of Enhanced Recovery After Surgery in Perioperative Nursing of Neurosurgery 加强术后恢复在神经外科围手术期护理中的应用现状
Pub Date : 2022-10-14 DOI: 10.26689/jcnr.v6i6.4407
Ying-kʿai Wu, Yuqing Liang, Hao Chen, Lixia Xue
Enhanced recovery after surgery (ERAS) is a strategy of perioperative management aimed to accelerate the rehabilitation of patients through various optimized perioperative managements as well as ongoing adherence to a patient-focused, multidisciplinary, and multimodal approach. ERAS is a good reflection of the perioperative value-based care, which has been widely applied in many surgical fields and shown quick recovery and low morbidity when applied on patients. However, there is a lack of attention on ERAS in neurosurgery. This review aims to describe the current application status of ERAS in neurosurgery and to provide readers with the commonly accepted principles in the perioperative nursing of neurosurgery.
增强术后恢复(ERAS)是一种围手术期管理策略,旨在通过各种优化的围手术期处理以及持续坚持以患者为中心、多学科和多模式的方法来加速患者的康复。ERAS很好地反映了围手术期基于价值的护理,该护理已在许多外科领域得到广泛应用,并在患者身上显示出快速恢复和低发病率。然而,神经外科对ERAS缺乏重视。本文旨在介绍ERAS在神经外科的应用现状,并为读者提供神经外科围手术期护理中公认的原则。
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引用次数: 0
Use of Danzhi Xiaoyao Powder in the Treatment of Diseases by Chief Physician Wang Defen: Case Examples 王德芬主任医师应用丹脂逍遥散治疗疾病例
Pub Date : 2022-09-30 DOI: 10.26689/jcnr.v6i5.4282
Ying Luo
Danzhi Xiaoyao powder was first introduced by Xue Ji, a Ming Dynasty physician, in the “Summary of Internal Medicine.” It is primarily used for treating the syndrome of liver depression transforming into heat and is widely used in the treatment of dermatology, internal medicine, gynecology, and other multi-system diseases. This medical prescription is aptly dispensed, its detoxification effect is strong, and it is a representative medical prescription for soothing the liver, strengthening the spleen and stomach, as well as eliminating heat stagnation. Chief Physician Wang Defen inherited the academic experience of the fifth batch of nationally known Chinese medicine experts, under the guidance of Professor Ji Haiwang, a notable Chinese medicine practitioner in Shaanxi Province and Professor Shi Bingyin, a renowned endocrinologist. Through follow-up studies, the various methods and empirical prescriptions of Danzhi Xiaoyao powder applied by Chief Physician Wang Defen in the treatment of common clinical diseases are summarized. They have been proven to have conclusive efficacy, thus providing guidance and reference for the dialectical treatment using traditional Chinese medicine.
丹脂逍遥散最早由明代医生薛济在《内科要略》中介绍,主要用于治疗肝郁化热证,广泛用于皮肤科、内科、妇科等多系统疾病的治疗。此方配法适宜,解毒作用强,是疏肝、健脾、胃、消热滞的代表方。王德芬主任医师继承了第五批全国知名中医专家的学术经验,师从陕西省著名中医师纪海旺教授和著名内分泌学家史炳银教授。通过随访研究,总结了王德芬主任医师丹芝逍遥散治疗临床常见病的各种方法和经验方。它们已被证明具有决定性的疗效,从而为中医辨证治疗提供了指导和参考。
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引用次数: 0
The Level of Expression and Diagnostic Value of Biomarkers in Tuberculous Pleurisy 生物标志物在结核性胸膜炎中的表达水平及诊断价值
Pub Date : 2022-09-30 DOI: 10.26689/jcnr.v6i5.4301
Lin Wang, Ying Qi, Suhong Qi
Objective: Observe and analyze the clinical significance of the differences in the expression levels of sCD163, haptoglobin and cytokines. Methods: 120 patients with tuberculous pleural effusion diagnosed in our hospital from January 2019 to December 2021 were randomly selected as the experimental group. On the other hand, 40 patients with non-tuberculous pleural effusion admitted in the same period were selected as the control group. The expression levels of sCD163, haptoglobin and cytokines were observed and analyzed. Results: The expression levels of sCD163 (?g/mL), haptoglobin (g/L), IL-6 (pg/mL) and IL-12 (pg/mL) of the control group were 31.26 ± 14.12, 32.14 ± 18.79, 401.23 ± 24.36 and 1.32 ± 0.14, respectively. As for the experimental group, the expression levels of sCD163 (?g/mL), haptoglobin (g/L), IL-6 (pg/mL) and IL-12 (pg/mL) were 74.12 ± 14.78, 113.25 ± 19.45, 612.12 ± 36.98 and 4.12 ± 0.56 respectively, and p < 0.05 which shows that the data was statistically significant. Conclusion: The level of inflammatory cytokines in the pleural fluid of tuberculous pleural effusion patients are higher, which can be used for the diagnosis of auxiliary tuberculous pleurisy. Tuberculous pleural effusion patients has a significantly increased expression levels of sCD163 and haptoglobin in the pleural fluid. The combination of sCD163 and haptoglobin in the diagnosis of tuberculous pleural effusion has higher clinical diagnostic value, and sCD163 and haptoglobin are not interfered by inflammatory factors in the diagnosis of tuberculous pleural effusion
目的:观察分析sCD163、触珠蛋白和细胞因子表达水平差异的临床意义。方法:随机选择2019年1月至2021年12月在我院确诊的120例结核性胸腔积液患者作为实验组。另一方面,选择同期收治的40例非结核性胸腔积液患者作为对照组。观察并分析sCD163、触珠蛋白和细胞因子的表达水平。结果:对照组sCD163(?g/mL)、触珠蛋白(g/L)、IL-6(pg/mL)和IL-12(pg/mL)的表达水平分别为31.26±14.12、32.14±18.79、401.23±24.36和1.32±0.14。实验组sCD163(?g/mL)、触珠蛋白(g/L)、IL-6(pg/mL)和IL-12(pg/mL)的表达水平分别为74.12±14.78、113.25±19.45、612.12±36.98和4.12±0.56,p<0.05,表明数据具有统计学意义。结论:结核性胸腔积液患者胸腔液中炎性细胞因子水平较高,可用于辅助性结核性胸膜炎的诊断。结核性胸腔积液患者胸腔液中sCD163和触珠蛋白的表达水平显著增加。sCD163与触珠蛋白联合诊断结核性胸腔积液具有较高的临床诊断价值,且sCD163和触珠蛋白在诊断结核性胸水时不受炎症因素干扰
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引用次数: 0
Clinical Efficacy of Dienogest and Levonorgestrel-Releasing Intrauterine System in the Treatment of Adenomyosis 炔诺孕酮和左炔诺孕酮释放宫内系统治疗乙型脑出血的临床疗效
Pub Date : 2022-09-30 DOI: 10.26689/jcnr.v6i5.4213
Yang Xu, Li Li, Guixia Yang
Objective: To compare the clinical efficacy and adverse reactions of dienogest and levonorgestrel-releasing intrauterine system in the treatment of adenomyosis. Methods: A total of 60 cases of adenomyosis admitted to Dezhou Women and Children’s Hospital from January 2020 to October 2021 were selected and randomly divided into two groups (Group A and Group B), which were initiated on dienogest and levonorgestrel-releasing intrauterine system, respectively. The therapeutic effects and adverse reactions of the two groups were analyzed. Results: After 6 months of treatment, the uterine volume in the LNG-IUS group reduced slightly compared with that before treatment, with no statistical significance (p > 0.05), while that in the DNG group increased slightly compared with that before treatment, with no statistical significance (p > 0.05). After 6 months of treatment, the hemoglobin of patients in both groups increased compared with that before treatment; there was no significant difference in the DNG group (p > 0.05), but there was significant difference in the LNG-IUS group (p < 0.01). After 6 months of treatment, the VAS scores of the two groups were significantly lower than those before treatment (p < 0.01); the serum CA125 level in both groups decreased significantly compared with that before treatment (p < 0.01). Conclusion: Mirena (levonorgestrel-releasing intrauterine system) has better therapeutic effect on adenomyosis and fewer adverse reactions than deinogest.
目的:比较地诺孕酮与左炔诺孕酮释放宫内系统治疗乙型脑出血的临床疗效及不良反应。方法:选择2020年1月至2021年10月在德州妇幼医院收治的子宫腺肌症患者60例,随机分为A组和B组,分别开始使用地诺孕酮和左炔诺孕酮释放宫内系统。分析两组患者的治疗效果及不良反应。结果:治疗6个月后,LNG-IUS组子宫体积较治疗前略有缩小,差异无统计学意义(p > 0.05); DNG组子宫体积较治疗前略有增大,差异无统计学意义(p > 0.05)。治疗6个月后,两组患者血红蛋白均较治疗前升高;DNG组间差异无统计学意义(p < 0.05), LNG-IUS组间差异有统计学意义(p < 0.01)。治疗6个月后,两组患者VAS评分均显著低于治疗前(p < 0.01);两组患者血清CA125水平均较治疗前显著降低(p < 0.01)。结论:mrena(释放左炔诺孕酮的宫内系统)治疗子宫腺肌症疗效好,不良反应少。
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引用次数: 0
Application Research of Detailed Nursing of Tuberculous Meningitis Patients 结核性脑膜炎详细护理的应用研究
Pub Date : 2022-09-29 DOI: 10.26689/jcnr.v6i5.4354
W. Yuan, Dandan Yang, Zhang Li, Chuo Guo, Xinyi Ye, Min Zheng
Objective: To explore the application effect of detailed nursing in tuberculous meningitis nursing. Methods: A total of 52 patients with tuberculous meningitis who were admitted to our hospital from May 2019 to February 2022 were selected as the research objects, and divided into 25 patients in the control group and 27 patients in the study group according to the random table method, and the compliance, quality of life, recurrence, nursing satisfaction, depression, anxiety and PSQI scores of the two groups were observed and analyzed. Results: In the study group, the number of patients with complete compliance, partial compliance and non-compliance were 13, 11 and 3, respectively, and the compliance rate was 88.89%. In the control group, the number of patients with complete compliance, partial compliance and non-compliance were 11, 5 and 9, respectively, and the compliance rate was 67.86 %, and P < 0.05 was considered statistically significant. The quality-of-life score of the control group was 48.36 ± 2.24, which was lower than that of the study group, 50.23 ± 2.12, (P < 0.05). The rate of recurrence of the control group was 36.00%, which was significantly higher than 7.41% in the study group (P < 0.05). There was no significant statistical difference between the SAS, SDS, and PSQI scores of the two groups before nursing, (P > 0.05). After nursing, both groups showed a decrease in SDS and SAS scores, with the study group showing significantly lower scores than the control group (P < 0.001). Besides, the PSQI dimension scores and total score in the study group were lower than those in the control group (P < 0.001). Moreover, the nursing satisfaction of the patients in the study group was significantly higher than that in the control group (93.02% > 71.79%), (P < 0.05). Conclusion: A full range of detailed care is not only helpful for accurate diagnosis and treatment of patients, but also helps to create a satisfactory hospital environment for patients. Results from this study showed that detailed nursing care for patients with tuberculous meningitis shows a significant positive effect and should be applied in clinical practices.
目的:探讨细致护理在结核性脑膜炎护理中的应用效果。方法:选取2019年5月至2022年2月我院收治的结核性脑膜炎患者52例作为研究对象,按随机表法分为对照组25例和研究组27例,观察分析两组患者的依从性、生活质量、复发、护理满意度、抑郁、焦虑、PSQI评分。结果:研究组完全依从13例,部分依从11例,不依从3例,依从率为88.89%。对照组完全依从、部分依从、不依从患者分别为11例、5例、9例,依从率为67.86%,P < 0.05有统计学意义。对照组患者的生活质量评分为48.36±2.24,低于研究组患者的50.23±2.12,差异有统计学意义(P < 0.05)。对照组复发率为36.00%,显著高于研究组的7.41% (P < 0.05)。两组患者护理前SAS、SDS、PSQI评分比较,差异均无统计学意义(P < 0.05)。护理后,两组患者SDS、SAS评分均下降,研究组得分显著低于对照组(P < 0.001)。研究组的PSQI维度得分和总分均低于对照组(P < 0.001)。研究组患者的护理满意度显著高于对照组(93.02% bb0 71.79%),差异有统计学意义(P < 0.05)。结论:全方位的细致护理不仅有助于患者的准确诊断和治疗,而且有助于为患者创造满意的医院环境。本研究结果表明,对结核性脑膜炎患者进行详细护理具有显著的积极作用,应在临床实践中加以应用。
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引用次数: 0
Study on Application Effect of 6S Management Mode in Infection Control Management of Fangcang Shelter Hospital of National Exhibition and Convention Center 6S管理模式在国家会展中心方舱方舱医院感染控制管理中的应用效果研究
Pub Date : 2022-09-29 DOI: 10.26689/jcnr.v6i5.4317
T. Sun, Ning Han, Ni Li, Zhi Zan, Dongxian Zhang
Objective: In 2022, a pneumonia caused by novel coronavirus broke out in Shanghai. A large number of medical personnel were deployed nationwide to support the Fangcang Shelter Hospital of National Exhibition and Convention Center (Shanghai). Because the of the underdeveloped infrastructure and the disorganized layout process, the phenomenon of infection among medical personnel was rampant given the highly contagious nature of the Omicron variant. This paper discusses the effect of 6S management in infection control management of Fangcang Shelter Hospital of National Exhibition and Convention Center (Shanghai). Methods: A series of 6S management practices were carried out based on the evaluation of the control management of Fangcang Shelter Hospital of National Exhibition and Convention Center (Shanghai) during the anti-epidemic period, and the effect of the implementation of 6S management was studied based on the rapport among team members and the overall control system process, the management of wearing and stripping channels, the time of wearing protective articles and the psychological and emotional changes of the team members. Results: After the implementation of 6S management mode, the management of dressing room, epidemic prevention materials, and occupational protection awareness and infection control safety were significantly improved. More than 95.5% of the team members believed that improving the working environment in the shelter increased the confidence of victory in the fight against the epidemic, reduced the preparations before entering and leaving the cabin, improved the work efficiency and ensured occupational safety. It ensures the realization of the goal of “zero infection” and is set as a benchmark of control work of Fangcang Shelter Hospital of National Exhibition and Convention Center (Shanghai). Conclusion: The application of 6S management mode to the shelter infection control management can create and maintain a good working environment in the shelter, promote the implementation effect of various systems and processes of infection control, reduce the potential infection risk in the shelter and improve the efficiency of infection control management.
目的:2022年,上海爆发了一场新型冠状病毒感染的肺炎。国家会展中心(上海)方仓方舱医院在全国范围内部署了大量医护人员。由于基础设施不发达和布局过程混乱,鉴于欧米克隆变异的高传染性,医务人员之间的感染现象十分猖獗。探讨6S管理在国家会展中心(上海)方仓方舱医院感染控制管理中的效果。方法:在对国家会展中心(上海)方仓方舱医院防疫期间控制管理进行评价的基础上,开展了一系列6S管理实践,并从团队成员之间的关系、整体控制系统流程、穿脱渠道管理、穿戴防护用品的时间和队员的心理情绪变化。结果:实施6S管理模式后,更衣室管理、防疫物资管理、职业防护意识和感染控制安全均有明显提高。超过95.5%的队员认为,改善棚内工作环境,增强了战胜疫情的信心,减少了进出舱内的准备工作,提高了工作效率,保障了职业安全。确保了“零感染”目标的实现,被树立为国家会展中心(上海)方仓方舱医院防控工作的标杆。结论:将6S管理模式应用于收容所感染控制管理,可以在收容所创造和保持良好的工作环境,促进感染控制各项制度和流程的实施效果,降低收容所潜在感染风险,提高感染控制管理效率。
{"title":"Study on Application Effect of 6S Management Mode in Infection Control Management of Fangcang Shelter Hospital of National Exhibition and Convention Center","authors":"T. Sun, Ning Han, Ni Li, Zhi Zan, Dongxian Zhang","doi":"10.26689/jcnr.v6i5.4317","DOIUrl":"https://doi.org/10.26689/jcnr.v6i5.4317","url":null,"abstract":"Objective: In 2022, a pneumonia caused by novel coronavirus broke out in Shanghai. A large number of medical personnel were deployed nationwide to support the Fangcang Shelter Hospital of National Exhibition and Convention Center (Shanghai). Because the of the underdeveloped infrastructure and the disorganized layout process, the phenomenon of infection among medical personnel was rampant given the highly contagious nature of the Omicron variant. This paper discusses the effect of 6S management in infection control management of Fangcang Shelter Hospital of National Exhibition and Convention Center (Shanghai). Methods: A series of 6S management practices were carried out based on the evaluation of the control management of Fangcang Shelter Hospital of National Exhibition and Convention Center (Shanghai) during the anti-epidemic period, and the effect of the implementation of 6S management was studied based on the rapport among team members and the overall control system process, the management of wearing and stripping channels, the time of wearing protective articles and the psychological and emotional changes of the team members. Results: After the implementation of 6S management mode, the management of dressing room, epidemic prevention materials, and occupational protection awareness and infection control safety were significantly improved. More than 95.5% of the team members believed that improving the working environment in the shelter increased the confidence of victory in the fight against the epidemic, reduced the preparations before entering and leaving the cabin, improved the work efficiency and ensured occupational safety. It ensures the realization of the goal of “zero infection” and is set as a benchmark of control work of Fangcang Shelter Hospital of National Exhibition and Convention Center (Shanghai). Conclusion: The application of 6S management mode to the shelter infection control management can create and maintain a good working environment in the shelter, promote the implementation effect of various systems and processes of infection control, reduce the potential infection risk in the shelter and improve the efficiency of infection control management.","PeriodicalId":64151,"journal":{"name":"临床护理研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46021896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Observation on the Treatment of Early Pre-Eclampsia Abortion with the Combination of Enhanced “Shou Tai Wan” Soup and Progesterone “寿台丸”汤加用黄体酮治疗早期子痫前期流产的临床观察
Pub Date : 2022-09-29 DOI: 10.26689/jcnr.v6i5.4330
Yao Chen, Yu Cao, Huifang Li
Objective: To investigate the clinical efficacy of the combination of enhanced “Shou Tai Wan” soup and progesterone in the treatment of early pre-eclampsia miscarriage. Methods: 86 patients with early pre-eclampsia miscarriage in our hospital from July 2021 to July 2022 were selected and randomly divided into two groups of 43 cases each. The control group was treated with progesterone, while the study group was treated with an addition of enhanced “Shou Tai Wan” soup. The treatment effects of the two groups and the changes in the inflammatory factor levels and sex hormone levels before and after the treatment were observed. Results: INF-? and Il-2 were lower and IL-4 was higher in the study group than in the control group after treatment (p-value < 0.05); the total effective rate of treatment was higher in the study group (95.35%) than in the control group (74.42%), (p-value < 0.05); the levels of P, E2 and ?-hCG were higher in the study group than in the control group after treatment (p-value < 0.05). Conclusion: The combined application of enhanced “Shou Tai Wan” soup and progesterone in patients with early preterm abortion is more effective by improving the patients’ sex hormone levels and reducing the level of inflammatory factors, which is conducive to the improvement of the treatment effect and worthy of promotion.
目的:观察“寿泰丸”加减配合黄体酮治疗早期子痫前期流产的临床疗效。方法:选择我院2021年7月至2022年7月收治的86例早期子痫前期流产患者,随机分为两组,每组43例。对照组用黄体酮治疗,研究组加用“寿泰丸”加减。观察两组治疗效果及治疗前后炎症因子水平和性激素水平的变化。结果:INF-?研究组治疗后血清Il-1、Il-1、Il-2水平均低于对照组,Il-4水平高于对照组(p值<0.05);治疗组总有效率(95.35%)高于对照组(74.42%)(p值<0.05);P、E2和-结论:复方寿泰丸汤联合黄体酮治疗早期早产患者,可提高患者性激素水平,降低炎症因子水平,有利于提高治疗效果,值得推广。
{"title":"Clinical Observation on the Treatment of Early Pre-Eclampsia Abortion with the Combination of Enhanced “Shou Tai Wan” Soup and Progesterone","authors":"Yao Chen, Yu Cao, Huifang Li","doi":"10.26689/jcnr.v6i5.4330","DOIUrl":"https://doi.org/10.26689/jcnr.v6i5.4330","url":null,"abstract":"Objective: To investigate the clinical efficacy of the combination of enhanced “Shou Tai Wan” soup and progesterone in the treatment of early pre-eclampsia miscarriage. Methods: 86 patients with early pre-eclampsia miscarriage in our hospital from July 2021 to July 2022 were selected and randomly divided into two groups of 43 cases each. The control group was treated with progesterone, while the study group was treated with an addition of enhanced “Shou Tai Wan” soup. The treatment effects of the two groups and the changes in the inflammatory factor levels and sex hormone levels before and after the treatment were observed. Results: INF-? and Il-2 were lower and IL-4 was higher in the study group than in the control group after treatment (p-value < 0.05); the total effective rate of treatment was higher in the study group (95.35%) than in the control group (74.42%), (p-value < 0.05); the levels of P, E2 and ?-hCG were higher in the study group than in the control group after treatment (p-value < 0.05). Conclusion: The combined application of enhanced “Shou Tai Wan” soup and progesterone in patients with early preterm abortion is more effective by improving the patients’ sex hormone levels and reducing the level of inflammatory factors, which is conducive to the improvement of the treatment effect and worthy of promotion.","PeriodicalId":64151,"journal":{"name":"临床护理研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43209337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cultivation Path of Compound Talents in Ophthalmic Diagnosis, Treatment, and Nursing Based on Artificial Intelligence 基于人工智能的眼科诊疗护理复合型人才培养路径
Pub Date : 2022-09-29 DOI: 10.26689/jcnr.v6i5.4387
Hongyan Xu, Jiaxin Chen, Tingting Tang, Shouhua Yang
Artificial intelligence can effectively improve the efficiency and accuracy of medical diagnosis, clinical data analysis, medical image recognition, treatment plan decision-making, etc. It has broad application prospects in the ophthalmic diagnosis, treatment, and nursing industry. However, the application of artificial intelligence in the ophthalmic diagnosis and nursing industry in China started relatively late, and there are insufficient ophthalmic diagnosis and nursing personnel who are familiar with artificial intelligence technologies. In order to promote the modernization of ophthalmic medicine in China and accelerate the development of a high-quality and modern medical education system, it is necessary to train a new generation of compound ophthalmic medical talents who are skilled in artificial intelligence and develop an advanced talent training model that meets the needs of the ophthalmic profession and the society. Based on the application status and development prospects of artificial intelligence in the ophthalmology industry, this paper analyzes the current medical education model in ophthalmology, examines the path of cultivating compound talents in ophthalmic diagnosis, treatment, and nursing, as well as proposes suggestions for developing a high-quality and modern medical education system.
人工智能可以有效提高医学诊断、临床数据分析、医学图像识别、治疗方案决策等方面的效率和准确性。在眼科诊断、治疗、护理行业具有广阔的应用前景。然而,人工智能在国内眼科诊断护理行业的应用起步较晚,熟悉人工智能技术的眼科诊断护理人员不足。为推动中国眼科医学现代化,加快建设高质量的现代医学教育体系,有必要培养新一代熟练掌握人工智能的复合型眼医学人才,发展适应眼科专业和社会需要的先进人才培养模式。基于人工智能在眼科行业的应用现状和发展前景,分析了目前眼科医学教育模式,探讨了培养眼科诊断、治疗、护理复合型人才的路径,并提出了构建高质量、现代化的医学教育体系的建议。
{"title":"Cultivation Path of Compound Talents in Ophthalmic Diagnosis, Treatment, and Nursing Based on Artificial Intelligence","authors":"Hongyan Xu, Jiaxin Chen, Tingting Tang, Shouhua Yang","doi":"10.26689/jcnr.v6i5.4387","DOIUrl":"https://doi.org/10.26689/jcnr.v6i5.4387","url":null,"abstract":"Artificial intelligence can effectively improve the efficiency and accuracy of medical diagnosis, clinical data analysis, medical image recognition, treatment plan decision-making, etc. It has broad application prospects in the ophthalmic diagnosis, treatment, and nursing industry. However, the application of artificial intelligence in the ophthalmic diagnosis and nursing industry in China started relatively late, and there are insufficient ophthalmic diagnosis and nursing personnel who are familiar with artificial intelligence technologies. In order to promote the modernization of ophthalmic medicine in China and accelerate the development of a high-quality and modern medical education system, it is necessary to train a new generation of compound ophthalmic medical talents who are skilled in artificial intelligence and develop an advanced talent training model that meets the needs of the ophthalmic profession and the society. Based on the application status and development prospects of artificial intelligence in the ophthalmology industry, this paper analyzes the current medical education model in ophthalmology, examines the path of cultivating compound talents in ophthalmic diagnosis, treatment, and nursing, as well as proposes suggestions for developing a high-quality and modern medical education system.","PeriodicalId":64151,"journal":{"name":"临床护理研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44165241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anti-Anxiety Effects of Prelimbic 5-HT4 Receptors in the Rat Model of Parkinson’s Disease: Evidence from Behavioral and Electrophysiological Study 大鼠帕金森病模型中边缘前5-HT4受体的抗焦虑作用:来自行为和电生理的证据
Pub Date : 2022-09-29 DOI: 10.26689/jcnr.v6i5.4363
Yu-ming Zhang, N. Bai, Hui Wang, J. Wang
Objective: Clinical and laboratory studies have demonstrated that prelimbic (PrL) and serotonin-4 (5-HT4) receptors may have the key role in regulating anxiety. However, the pathophysiology of anxiety in Parkinson’s disease (PD) remains obscure. In this research, the effects of PrL 5-HT4 receptors on anti-anxiety behaviors in hemiparkinsonian rats were investigated. Methods: PD model rats were used as the research subjects, starting with behavioral changes, from the point of view of electrophysiology, the regulatory effect of PrL 5-HT4 receptors on PD-related anxiety and the possible mechanism were explored. Results: Anxiety-like behaviors were induced via MFB lesion in rats. Intra-PrL injection of 5-HT4 receptors agonist RS67333 induced anti-anxiety effects in both sham and PD group. In the sham group, PrL administration of 5-HT4 receptors antagonist SB204070 produce anti-anxiety effects, but in the PD group, the expression of anxiety-like behavior was increased. Compared to the sham group, the effective dose of the behavioral effects of the two drugs in the PD group was obviously higher. Electrophysiological data suggested that PrL administration of RS67333 (SB204070) increased (decreased) the ?ring activities of ?-aminobutyric acid (GABA) neurons in both groups. Compared with rats in sham group, lesioned rats had a shorter duration of the excitation (inhibition) effects on firing activities of GABA neurons. Conclusion: PrL 5-HT4 receptors regulate anxiety behaviors in PD rats, and its mechanism may be related to the down-regulation of expression or function of PrL 5-HT4 receptors in PD.
目的:临床和实验室研究表明,前边缘(PrL)和5-羟色胺-4 (5-HT4)受体可能在调节焦虑中起关键作用。然而,帕金森病(PD)中焦虑的病理生理机制尚不清楚。本研究探讨prl5 - ht4受体对偏帕金森大鼠抗焦虑行为的影响。方法:以PD模型大鼠为研究对象,从行为改变入手,从电生理学角度探讨prl5 - ht4受体对PD相关焦虑的调节作用及其可能的机制。结果:MFB损伤诱导大鼠焦虑样行为。prl内注射5-HT4受体激动剂RS67333诱导假手术组和PD组的抗焦虑作用。假手术组PrL给药5-HT4受体拮抗剂SB204070具有抗焦虑作用,PD组焦虑样行为表达增加。与假手术组相比,PD组两种药物的行为效应有效剂量明显较高。电生理数据显示,PrL给药RS67333 (SB204070)增加(降低)了两组γ -氨基丁酸(GABA)神经元的γ环活性。与假手术组相比,损伤大鼠对GABA神经元放电活动的兴奋(抑制)作用持续时间较短。结论:prl5 - ht4受体调节PD大鼠焦虑行为,其机制可能与prl5 - ht4受体在PD中的表达或功能下调有关。
{"title":"Anti-Anxiety Effects of Prelimbic 5-HT4 Receptors in the Rat Model of Parkinson’s Disease: Evidence from Behavioral and Electrophysiological Study","authors":"Yu-ming Zhang, N. Bai, Hui Wang, J. Wang","doi":"10.26689/jcnr.v6i5.4363","DOIUrl":"https://doi.org/10.26689/jcnr.v6i5.4363","url":null,"abstract":"Objective: Clinical and laboratory studies have demonstrated that prelimbic (PrL) and serotonin-4 (5-HT4) receptors may have the key role in regulating anxiety. However, the pathophysiology of anxiety in Parkinson’s disease (PD) remains obscure. In this research, the effects of PrL 5-HT4 receptors on anti-anxiety behaviors in hemiparkinsonian rats were investigated. Methods: PD model rats were used as the research subjects, starting with behavioral changes, from the point of view of electrophysiology, the regulatory effect of PrL 5-HT4 receptors on PD-related anxiety and the possible mechanism were explored. Results: Anxiety-like behaviors were induced via MFB lesion in rats. Intra-PrL injection of 5-HT4 receptors agonist RS67333 induced anti-anxiety effects in both sham and PD group. In the sham group, PrL administration of 5-HT4 receptors antagonist SB204070 produce anti-anxiety effects, but in the PD group, the expression of anxiety-like behavior was increased. Compared to the sham group, the effective dose of the behavioral effects of the two drugs in the PD group was obviously higher. Electrophysiological data suggested that PrL administration of RS67333 (SB204070) increased (decreased) the ?ring activities of ?-aminobutyric acid (GABA) neurons in both groups. Compared with rats in sham group, lesioned rats had a shorter duration of the excitation (inhibition) effects on firing activities of GABA neurons. Conclusion: PrL 5-HT4 receptors regulate anxiety behaviors in PD rats, and its mechanism may be related to the down-regulation of expression or function of PrL 5-HT4 receptors in PD.","PeriodicalId":64151,"journal":{"name":"临床护理研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41697217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preserving Spontaneous Breathing Without Intubation and Endotracheal Intubation with One Lung Ventilation in Single-hole Thoracoscopic Bulla Suture 单孔胸腔镜下保自主呼吸不插管与单肺通气气管插管大疱缝合术
Pub Date : 2022-09-29 DOI: 10.26689/jcnr.v6i5.4310
Hefei Li, Pei Liu, Yanhong Shang, Zhi-min Guo, Biao Zhang, Kuo Xiao, Qiang Guo, Xianyi Liu
Objective: To explore the situation of patients and the compare the effect between two methods, which are preserving spontaneous breathing without intubation and endotracheal intubation with one lung ventilation in the single-hole thoracoscopic bulla suture. Method: 42 patients who received single-hole thoracoscopic pulmonary bullae suture in our hospital from January 2020 to December 2021 were selected as the study subjects, including 19 patients who underwent endotracheal intubation and one lung ventilation as the control group and 23 patients who underwent single-hole thoracoscopic pulmonary bullae suture without intubation as the study group. The relevant indexes, postoperative general conditions, complications and pneumothorax recurrence of the two groups were analyzed and observed. Results: In the control group, the scores of anesthesia time (points), resuscitation time (points), surgical visual field score (points), surgical time (points), and surgical bleeding volume (points) were 20.8 ± 4.6, 19.9 ± 7.9, 1.7 ± 0.5, 44.9 ± 7.9, and 11.4 ± 2.4 respectively. In the study group, the scores of anesthesia time (points), resuscitation time (points), surgical visual field score (points), surgical time (points), and scores of surgical bleeding (points) were 17.9 ± 4.3, 15.4 ± 3.4, 1.9 ± 0.4, 48.4 ± 7.1, 10.9 ± 2.2, respectively. There was no statistical difference in surgical visual field score, surgical time and surgical bleeding whereas there was a statistical difference between anesthesia time and resuscitation time. In the control group after operation, VAS score at 6 hours after operation, SaO2 (%) after operation, PaCO2 (mmHg) after operation, drainage volume (ML) after operation, feeding time (H) after operation, retention time of thoracic tube after operation (H), WBC (109) on the first day after operation, hospitalization time (d), and total hospitalization cost (RMB 1000) were 2.1 ± 0.7, 98.2 ± 1.4, 42.4 ± 4.9, 139.1 ± 23.1, 6.9 ± 1.6, 37.1 ± 5.4, 7.9 ± 2.1, 6.6 ± 1.3, and 2.6 ± 0.3 respectively. As for the study group, the VAS score at 6 hours after operation, SaO2 (%) after operation, PaCO2 (mmHg) after operation, drainage volume (ML) after operation, feeding time (H) after operation, retention time of thoracic tube after operation (H), WBC (109) on the first day after operation, hospitalization time (d), and total hospitalization cost (RMB 1000) were 1.9 ± 0.4, 97.9 ± 1.2, 42.8 ± 5.1, 151.8 ± 21.9, 4.3 ± 1.4, 15.3 ± 2.6, 5.2 ± 2.3, 4.2 ± 1.2, and 1.8 ± 0.4 respectively. Among them, there were no significant differences in visual analog scale (VAS) score at 6 hours after operation, SaO2 after operation and PaCO2 after operation between the two groups, but there were significant differences in other factors. The complication rate of the control group was 36.84%, which was significantly higher than that of the study group (4.35%), with statistical difference. The recurrence rate of the control group was 21.05%, which was not significantl
目的:探讨单孔胸腔镜大球缝合中保留自主呼吸不插管与气管插管单肺通气两种方法的疗效比较。方法:选取2020年1月至2021年12月在我院行单孔胸腔镜肺大泡缝合术的患者42例作为研究对象,其中气管插管加一次肺通气的患者19例为对照组,不插管行单孔胸腔镜肺大泡缝合术的患者23例为研究组。分析观察两组患者的相关指标、术后一般情况、并发症及气胸复发情况。结果:对照组麻醉时间(分)、复苏时间(分)、手术视野评分(分)、手术时间(分)、手术出血量(分)分别为20.8±4.6、19.9±7.9、1.7±0.5、44.9±7.9、11.4±2.4。研究组麻醉时间(分)、复苏时间(分)、手术视野评分(分)、手术时间(分)、手术出血评分(分)分别为17.9±4.3、15.4±3.4、1.9±0.4、48.4±7.1、10.9±2.2。手术视野评分、手术时间、手术出血量差异无统计学意义,麻醉时间与复苏时间差异有统计学意义。对照组术后,脉管的分数在手术后6小时,SaO2(%)操作后,PaCO2操作后(毫米汞柱),排水体积(ML)操作后,喂食的时候(H)操作后,保留时间的胸管后操作(H),白细胞(109)术后第一天,住院时间(d),和住院总成本(1000元)2.1±0.7,98.2±1.4,42.4±4.9,139.1±23.1,6.9±1.6,37.1±5.4,7.9±2.1,6.6±1.3,2.6±0.3。至于学习小组,脉管分数在手术后6小时,SaO2(%)操作后,PaCO2操作后(毫米汞柱),排水体积(ML)操作后,喂食的时候(H)操作后,保留时间的胸管后操作(H),白细胞(109)术后第一天,住院时间(d),和住院总成本(1000元)1.9±0.4,97.9±1.2,42.8±5.1,151.8±21.9,4.3±1.4,15.3±2.6,5.2±2.3,4.2±1.2,1.8±0.4。其中,两组术后6 h视觉模拟评分(VAS)、术后SaO2、PaCO2比较差异无统计学意义,但其他因素比较差异有统计学意义。对照组并发症发生率为36.84%,显著高于研究组(4.35%),差异有统计学意义。对照组复发率为21.05%,与研究组复发率(4.35%)差异无统计学意义。结论:单孔胸腔镜大泡缝合无需插管,可减少患者麻醉时间和复苏时间,降低患者住院费用,减轻治疗负担,缩短首次喂养时间,减少患者并发症发生率。因此,值得临床推广。
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临床护理研究
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