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Study on the Risk Factors of Central Venous-Related Bloodstream Infection in Outpatients 门诊患者中心静脉相关血流感染危险因素的研究
Pub Date : 2023-07-27 DOI: 10.26689/jcnr.v7i4.5076
Lu Yan, Cuiyu Han, Xuerun Du, Y. Gu, R. Gao
Objective: To analyze the risk factors of catheter-related bloodstream infection in outpatients and propose feasible prevention and control measures. Methods: The medical records of outpatients with peripherally inserted central catheter (PICC) from January 2020 to December 2021 were selected for retrospective analysis, and the factors that may be related to the occurrence of catheter-related bloodstream infection were analyzed by logistic multivariate analysis. Results: The incidence rate of catheter-related bloodstream infection among the enrolled patients was 4.78%. It was found that age, duration of catheterization, catheter site, number of punctures, and diabetes were all risk factors for catheter-associated bloodstream infection, and the differences were statistically significant. Conclusion: Age, duration of catheterization, catheterization site, and diabetes are all risk factors for catheter-related bloodstream infection, and medical personnel should fully understand and learn more about these risk factors and actively develop countermeasures to reduce the risk of catheter-related bloodstream infection.
目的:分析门诊患者导管相关血流感染的危险因素,提出可行的防治措施。方法:选取2020年1月至2021年12月门诊PICC患者的病历进行回顾性分析,采用logistic多因素分析对可能与导管相关性血流感染发生相关的因素进行分析。结果:入组患者导管相关血流感染发生率为4.78%。发现年龄、置管时间、置管部位、穿刺次数、糖尿病均为导管相关血流感染的危险因素,差异有统计学意义。结论:年龄、置管时间、置管部位、糖尿病均是导管相关血流感染的危险因素,医务人员应充分认识和了解这些危险因素,积极制定对策,降低导管相关血流感染的风险。
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引用次数: 0
The Effect of MMP-9 Inhibitors on the Biological Behavior of Human Oral Squamous Cell Carcinoma SCC15 Cell Line Through PI3K/Akt Signaling Pathway MMP-9抑制剂通过PI3K/Akt信号通路对人口腔鳞状细胞癌SCC15细胞生物学行为的影响
Pub Date : 2023-07-25 DOI: 10.26689/jcnr.v7i4.5085
Zhizheng Zhuang, Yan Hu, Hongyue Liu
Objective: To investigate the effect of MMP-9 inhibitor (Mki67) on the biology of human oral squamous cell carcinoma SCC15 cell line and to explore its mechanism of action through PI3K/Akt signaling pathway. Methods: SCC15 cells were extracted, and the supernatant was discarded. The cells were then rinsed twice with PBS, and 0, 2.5, 5, and 10 μL of Mki67 (50 mg/mL) were added to the culture respectively. The inhibition rate of cell proliferation was detected by 3-(4, 5-dimethylthiazolyl-2)-2,5-diphenyltetrazolium bromide (MTT) method, and the cell migration was measured by Transwell chamber test. The cell apoptosis rate was detected by cytometry, and the p-Akt protein content in the cells of each group was determined by a double-antibody sandwich enzyme-linked immunosorbent assay (ELISA) kit. Results: The cell proliferation rates of the 2.5 μL, 5 μL, and 10 μL dose groups were all lower than the 0 μL group (P < 0.05) before treatment, and the cell proliferation rates in the 2.5 μL, 5μL, and 10μL dose groups decreased overtime (P < 0.05). After 24 h, with the increase of Mki67 concentration, the number of migration and invasion gradually decreased (P < 0.05), and the number of apoptosis gradually increased (P < 0.05); besides, the relative expression of MMP-9, PI3K, and Akt mRNA decreased gradually (P < 0.05), and the expression level of Akt mRNA was not statistically significant (P > 0.05). Conclusion: MMP-9 inhibitor (Mki67) can inhibit the proliferation and migration of SCC15 cell line and induce apoptosis, and its mechanism of action may be related to the inhibition of PI3K/Akt signaling pathway.
目的:研究基质金属蛋白酶9抑制剂(Mki67)对人口腔鳞状细胞癌SCC15细胞生物学的影响,并通过PI3K/Akt信号通路探讨其作用机制。方法:提取SCC15细胞,弃去上清液。然后用PBS冲洗细胞两次,并分别向培养物中加入0、2.5、5和10μL Mki67(50mg/mL)。用3-(4,5-二甲基噻唑基-2)-2,5-二苯基溴化四氮唑(MTT)法检测细胞增殖抑制率,用Transwell小室法测定细胞迁移。用细胞仪检测细胞凋亡率,用双抗体夹心酶联免疫吸附试验(ELISA)试剂盒测定各组细胞中p-Akt蛋白含量。结果:2.5μL、5μL和10μL剂量组的细胞增殖率均低于治疗前的0μL组(P<0.05),2.5μL和5μL、10μL浓度组的细胞生长率随时间的推移而下降(P<0.05),细胞凋亡数量逐渐增加(P<0.05);结论:MMP-9抑制剂(Mki67)可抑制SCC15细胞的增殖和迁移,诱导细胞凋亡,其作用机制可能与抑制PI3K/Akt信号通路有关。
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引用次数: 0
Epidemiological Survey on Vitamin A, D, E Levels of Pregnant Women in Baoding 保定市孕妇维生素A、D、E水平流行病学调查
Pub Date : 2023-07-12 DOI: 10.26689/jcnr.v7i4.5128
Bei Wang, Yakun Zhao, Hongli Wu, L. Liang, Wenli Kang, Yan-yan An, Jie Cui
Objective: To understand the vitamin levels in pregnant women and its influencing factors and provide a basis for formulating scientific and reasonable vitamin supplement plans for pregnant women. Methods: Pregnant women with a pregnancy period of 12 weeks to 36 weeks in Baoding area were selected as the research subjects using the random sampling method. The sample size is estimated to be 5,000 people, and the diversity of the research subjects, such as age, education level, pregnancy, etc., were recorded through a survey. The content of the survey included the personal information of the research subjects, pregnancy conditions, eating habits, vitamin supplements taken, etc. At the same time, blood tests were carried out on the research subjects to detect indicators such as vitamin levels. Results: The results of serum measurement showed that the vitamin A level of pregnant women was 0.38 ± 0.12 mg/L, the vitamin E level was 13.51 ± 3.17 mg/L, and the vitamin D level was 17.82 ± 4.18 ng/L; the level of vitamin A of pregnant women in the first trimester was significantly lower than those in the second and third trimesters, and the level of vitamin E of pregnant women in second trimester was significantly higher than those in the first and third trimesters, with statistically significant differences (P < 0.05). The rate of vitamin A deficiency in the early stage was significantly higher than that in the middle and late stages of pregnancy, (P < 0.05); vitamin D deficiency existed in all pregnant women. Conclusion: Pregnant women should maintain a reasonable diet and eat more vitamin-rich foods, such as vegetables, fruits, etc.; besides, pregnant women should take vitamin supplements under the guidance of doctors or professionals according to their own conditions; moreover, the publicity and education for pregnant women should be improved with more emphasis on vitamin supplementation.
目的:了解孕妇维生素水平及其影响因素,为制定科学合理的孕妇维生素补充计划提供依据。方法:采用随机抽样方法,选取保定地区妊娠12周到36周的孕妇为研究对象。样本量估计为5000人,通过调查记录了研究对象的多样性,如年龄、教育水平、怀孕等。调查内容包括研究对象的个人信息、怀孕情况、饮食习惯、服用的维生素补充剂等。同时,对研究对象进行血液测试,以检测维生素水平等指标。结果:孕妇血清维生素A水平为0.38±0.12 mg/L,维生素E水平为13.51±3.17 mg/L,维生素D水平为17.82±4.18 mg/L;孕早期孕妇的维生素A水平显著低于中、晚期,孕中期孕妇的维生素E水平显著高于中、晚期,妊娠早期维生素A缺乏率明显高于妊娠中后期(P<0.05);所有孕妇都存在维生素D缺乏症。结论:孕妇应保持合理饮食,多吃富含维生素的食物,如蔬菜、水果等。;此外,孕妇应根据自身情况在医生或专业人员的指导下服用维生素补充剂;此外,应加强对孕妇的宣传教育,更加重视补充维生素。
{"title":"Epidemiological Survey on Vitamin A, D, E Levels of Pregnant Women in Baoding","authors":"Bei Wang, Yakun Zhao, Hongli Wu, L. Liang, Wenli Kang, Yan-yan An, Jie Cui","doi":"10.26689/jcnr.v7i4.5128","DOIUrl":"https://doi.org/10.26689/jcnr.v7i4.5128","url":null,"abstract":"Objective: To understand the vitamin levels in pregnant women and its influencing factors and provide a basis for formulating scientific and reasonable vitamin supplement plans for pregnant women. Methods: Pregnant women with a pregnancy period of 12 weeks to 36 weeks in Baoding area were selected as the research subjects using the random sampling method. The sample size is estimated to be 5,000 people, and the diversity of the research subjects, such as age, education level, pregnancy, etc., were recorded through a survey. The content of the survey included the personal information of the research subjects, pregnancy conditions, eating habits, vitamin supplements taken, etc. At the same time, blood tests were carried out on the research subjects to detect indicators such as vitamin levels. Results: The results of serum measurement showed that the vitamin A level of pregnant women was 0.38 ± 0.12 mg/L, the vitamin E level was 13.51 ± 3.17 mg/L, and the vitamin D level was 17.82 ± 4.18 ng/L; the level of vitamin A of pregnant women in the first trimester was significantly lower than those in the second and third trimesters, and the level of vitamin E of pregnant women in second trimester was significantly higher than those in the first and third trimesters, with statistically significant differences (P < 0.05). The rate of vitamin A deficiency in the early stage was significantly higher than that in the middle and late stages of pregnancy, (P < 0.05); vitamin D deficiency existed in all pregnant women. Conclusion: Pregnant women should maintain a reasonable diet and eat more vitamin-rich foods, such as vegetables, fruits, etc.; besides, pregnant women should take vitamin supplements under the guidance of doctors or professionals according to their own conditions; moreover, the publicity and education for pregnant women should be improved with more emphasis on vitamin supplementation.","PeriodicalId":64151,"journal":{"name":"临床护理研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47559585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Application of Whole-Process Management in Day Surgery for Endometrial Polyp 全程管理在子宫内膜息肉日间手术中的应用
Pub Date : 2023-07-11 DOI: 10.26689/jcnr.v7i4.5135
Min Xia, Zhiqin Yin
Objective: To explore the effect of whole-process management model in nursing management of endometrial polyp day surgery. Methods: 266 patients that underwent endometrial polyp day surgery from January to December 2022 were selected for this study, and they were separated into an observation group (131 patients) and a control group (135 patients); the clinical data of the two groups were compared. Results: After intervention, the scores of Hamilton Anxiety Scale (HAM-A) of the patients in the observation group were lower than those in the control group (P < 0.05). The rate of postoperative complications in the observation group was lower than that in the control group (P < 0.05), and the satisfaction degree of the patients in the observation group was higher than that in the control group (P < 0.05). Conclusion: The application of the whole-course management model in endometrial polyp day surgery can alleviate patients’ anxiety, ensure the quality and safety of day surgery nursing, and improve patients’ satisfaction.
目的:探讨全程管理模式在子宫内膜息肉日间手术护理管理中的作用。方法:选择2022年1月至12月接受子宫内膜息肉日间手术的266例患者,分为观察组(131例)和对照组(135例);比较两组患者的临床资料。结果:干预后观察组患者汉密尔顿焦虑量表(HAM-A)评分低于对照组(P<0.05),观察组患者的满意度高于对照组(P<0.05)。结论:全程管理模式在子宫内膜息肉日间手术中的应用,可以缓解患者的焦虑,保证日间手术护理的质量和安全,提高患者的满意度。
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引用次数: 0
Observation on the Application Effect of Targeted Infusion Safety Nursing in Inpatients with Cancer 癌症住院患者靶向输液安全护理应用效果观察
Pub Date : 2023-07-06 DOI: 10.26689/jcnr.v7i4.5003
Xue Jin, Wenfeng Li
Objective: To study the clinical effect of targeted infusion safety nursing during infusion of inpatients with cancer. Methods: From January 1, 2020, to January 1, 2023, a total of 6,614 infusion patients were treated in The First Affiliated Hospital of Wenzhou Medical University, and 300 inpatients with cancer were selected as the research objects and randomly divided into the observation group and the control group, with 150 patients in each group. The control group received routine infusion nursing, and the observation group received targeted infusion safety nursing. The targeted infusion safety nursing was judged by comparing the nursing quality assessment, incidence of adverse events, patient compliance, and patients’ mastery of infusion knowledge between the two groups. clinical effect. Results: After the targeted infusion safety nursing was given to the patients in the observation group, the patients in this group recognized the nursing quality, and the statistical score was higher than that in the control group; the incidence of adverse events in the observation group was lower than that in the control group. The compliance of the observation group was higher than that of the control group. The mastery of health knowledge in the observation group was also higher than that in the control group and the difference was statistically significant (P < 0.02). Conclusion: After implementing targeted infusion safety nursing for inpatients with cancer, it can effectively prevent the occurrence of adverse events, improve patient compliance, and increase the mastery of relevant knowledge of patients.
目的:探讨肿瘤住院患者输液过程中针对性输液安全护理的临床效果。方法:选取温州医科大学附属第一医院2020年1月1日至2023年1月1日收治的输液患者6614例,其中300例住院肿瘤患者为研究对象,随机分为观察组和对照组,每组150例。对照组患者给予常规输液护理,观察组患者给予针对性输液安全护理。通过比较两组患者的护理质量评估、不良事件发生率、患者依从性、患者对输液知识的掌握情况,判断是否进行了针对性的输液安全护理。临床效果。结果:观察组患者在给予针对性输液安全护理后,该组患者对护理质量的认知度较高,且统计评分高于对照组;观察组不良事件发生率低于对照组。观察组患者的依从性高于对照组。观察组患者对健康知识的掌握程度也高于对照组,差异有统计学意义(P < 0.02)。结论:对住院肿瘤患者实施针对性输液安全护理后,可有效预防不良事件的发生,提高患者依从性,增加患者对相关知识的掌握。
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引用次数: 0
Effect Analysis of WeChat Platform Combined with PBL Teaching Method for Standardized Training of Residents in Anesthesiology Department 微信平台结合PBL教学法对麻醉科住院医师规范化培训的效果分析
Pub Date : 2023-07-06 DOI: 10.26689/jcnr.v7i4.5009
Xiaoyan Sun, Jiang Shen
Objective: To explore and analyze the effect of the WeChat platform combined with the PBL teaching method in the standardized training of anesthesia residents. Methods: 120 anesthesiology residents from January 2018 to the end of December 2019 were selected, and divided into a control group and an observation group of 60 each according to the time sequence of admission. The control group adopted the conventional teaching mode, and the observation group adopted the WeChat platform combined PBL teaching method. The scores of theoretical knowledge and anesthesia skills operation after training, the scores of the teaching interest survey, and the satisfaction with the teaching mode between the two groups were compared. Results: The scores of theoretical knowledge and anesthesia skills operation in the observation group were significantly higher than those in the control group, and the indicators of teaching interest in the observation group were also higher than those in the control group. The differences were statistically significant (P < 0.05). The satisfaction degree of the observation group was significantly higher than that of the control group, and the difference was also statistically significant (P < 0.05). Conclusion: The WeChat platform combined with the PBL teaching method is beneficial to improve the training effect of anesthesiology residents, stimulating autonomous learning ability, ensuring the effective practice of theoretical knowledge, and promoting them to move towards a higher standard of anesthesia skills.
目的:探讨和分析微信平台结合PBL教学法在麻醉住院医师规范化培训中的效果。方法:选择2018年1月~ 2019年12月底麻醉住院医师120人,按入院时间先后顺序分为对照组和观察组各60人。对照组采用常规教学模式,观察组采用微信平台结合PBL教学方法。比较两组学生培训后的理论知识和麻醉技能操作得分、教学兴趣调查得分及对教学模式的满意度。结果:观察组在理论知识、麻醉技能操作两项得分均显著高于对照组,教学兴趣指标均显著高于对照组。差异有统计学意义(P < 0.05)。观察组患者满意度显著高于对照组,差异也有统计学意义(P < 0.05)。结论:微信平台结合PBL教学法有利于提高麻醉住院医师培训效果,激发自主学习能力,保证理论知识的有效实践,促进其向更高水平的麻醉技能迈进。
{"title":"Effect Analysis of WeChat Platform Combined with PBL Teaching Method for Standardized Training of Residents in Anesthesiology Department","authors":"Xiaoyan Sun, Jiang Shen","doi":"10.26689/jcnr.v7i4.5009","DOIUrl":"https://doi.org/10.26689/jcnr.v7i4.5009","url":null,"abstract":"Objective: To explore and analyze the effect of the WeChat platform combined with the PBL teaching method in the standardized training of anesthesia residents. Methods: 120 anesthesiology residents from January 2018 to the end of December 2019 were selected, and divided into a control group and an observation group of 60 each according to the time sequence of admission. The control group adopted the conventional teaching mode, and the observation group adopted the WeChat platform combined PBL teaching method. The scores of theoretical knowledge and anesthesia skills operation after training, the scores of the teaching interest survey, and the satisfaction with the teaching mode between the two groups were compared. Results: The scores of theoretical knowledge and anesthesia skills operation in the observation group were significantly higher than those in the control group, and the indicators of teaching interest in the observation group were also higher than those in the control group. The differences were statistically significant (P < 0.05). The satisfaction degree of the observation group was significantly higher than that of the control group, and the difference was also statistically significant (P < 0.05). Conclusion: The WeChat platform combined with the PBL teaching method is beneficial to improve the training effect of anesthesiology residents, stimulating autonomous learning ability, ensuring the effective practice of theoretical knowledge, and promoting them to move towards a higher standard of anesthesia skills.","PeriodicalId":64151,"journal":{"name":"临床护理研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41939589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Research Progress of Perioperative Application of GLP-1 and Its Protective Effects on Organs GLP-1在围手术期应用及其对器官保护作用的研究进展
Pub Date : 2023-07-05 DOI: 10.26689/jcnr.v7i4.5033
H. Xi, Zhigang Pang, Yifan Liu, Lixiong Xue, Jiandong He, Wenqu Yang
Glucagon-like peptide-1 (GLP-1) is a multifunctional hormone with broad pharmacological potential to control inflammation, protect cardiovascular, kidney, and liver functions. Moreover, GLP-1 can also cross the blood-brain barrier and bind with GLP-1R distributed in various parts of the brain, thereby reducing apoptosis caused by neuroinflammation and oxygen stress, and promoting learning, memory, cognitive function, neuroprotection, and nerve cell remodeling. However, the exact molecular pathway by which GLP-1 receptor agonists (GLP-1RAs) exerts protective effects on many organs is not fully understood, so it is a hot topic of research. In this article, the recent research on the multi-organ protection of GLP-1 is reviewed, with emphasis on the research progress in the field of nervous system and perioperative anesthesia.
胰高血糖素样肽-1 (GLP-1)是一种多功能激素,具有广泛的药理潜力,可控制炎症,保护心血管、肾脏和肝脏功能。此外,GLP-1还能穿过血脑屏障,与分布在大脑各部位的GLP-1R结合,从而减少神经炎症和氧应激引起的细胞凋亡,促进学习、记忆、认知功能、神经保护和神经细胞重塑。然而,GLP-1受体激动剂(GLP-1RAs)对许多器官发挥保护作用的确切分子途径尚不完全清楚,是研究的热点。本文综述了近年来GLP-1在多器官保护方面的研究进展,重点介绍了GLP-1在神经系统和围手术期麻醉领域的研究进展。
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引用次数: 0
Construction of a New Model of Contactless Medical Services for Outpatients Based on the Project-Achieving Quality Control Circle 基于项目实现质量控制圈的门诊非接触式医疗服务新模式的构建
Pub Date : 2023-07-05 DOI: 10.26689/jcnr.v7i4.4953
Shuang Chen, Zhihong Guo, X. Huang, Zhiqin Yin
Objective: To carry out empirical research on the role of project-achieving quality control circle (QCC) in constructing a new model of contactless medical service for outpatients. Methods: A QCC, consisting of information office members from a grade A tertiary hospital in Wenzhou, was established to conduct a research project with the theme “Constructing a new model of contactless medical service based on outpatients’ experience.” According to the ten steps and PDCA cycle, an analysis was carried out before and after the QCC activities, focusing on improving pre-consultation services, providing steward-like services, and facilitating post-consultation management. Results: After the QCC activities, the mobile appointment rate, missed appointment rate, the proportion of smart check-ins, and the average check-in time were 55.68%, 4.02%, 39.75%, and 8.24 ± 3.66 min, respectively; in contrast, before the activities, they were 32.00%, 7.88%, 0.00%, and 14.96 ± 4.98 min, respectively; the difference between the two groups was statistically significant (χ2 = 3480.112, 4994.496; Fisher’s exact probability = 963788.570; t = 5.323, P < 0.001). Many experts have also visited the hospital to learn about this system, thus rendering social and economic benefits. Conclusion: Project-achieving QCC activities are suitable for complex situations, such as constructing a new model of contactless medical service, and can significantly improve outpatient service quality, enhance patients’ experience, and improve the abilities of circle members.
目的:对项目实现质量控制圈(QCC)在构建门诊无接触医疗服务新模式中的作用进行实证研究。方法:建立由温州市某三甲医院信息办公室成员组成的QCC,开展主题为“构建基于门诊体验的非接触式医疗服务新模式”的研究项目,重点改进会诊前服务,提供管家式服务,方便会诊后管理。结果:QCC活动后,移动预约率、错过预约率、智能登记比例和平均登记时间分别为55.68%、4.02%、39.75%和8.24±3.66分钟;相反,活动前分别为32.00%、7.88%、0.00%和14.96±4.98min;两组间差异有统计学意义(χ2=3480.112,4994.496;Fisher精确概率=936788.570;t=5.323,P<0.001),许多专家也到医院了解该系统,取得了社会效益和经济效益。结论:项目实现QCC活动适用于复杂的情况,如构建新的无接触医疗服务模式,可以显著提高门诊服务质量,增强患者体验,提高圈子成员的能力。
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引用次数: 0
Introduction of clinical research progress, mechanism analysis and application prospect of acupuncture and moxibustion when treating diabetic constipation 针灸治疗糖尿病便秘的临床研究进展、机理分析及应用前景介绍
Pub Date : 2023-06-21 DOI: 10.26689/jcnr.v7i4.5035
Leyao Qin, Z. Lei
Chronic diseases like diabetes, hypertension, and coronary heart disease are increasingly prevalent in Chinese ageing population due to its accelerated ageing process, which has been a serious threat to people's health. The prevention and treatment of these diseases have received increasing attention from the medical sector. Diabetes is a metabolic disease characterized by polydipsia, polyuria and emaciation, in which the incidence of type 2 diabetes is much higher compared to type 1 diabetes. Diabetes has a variety of complications that can occur after the progression of the disease. Diabetic constipation is one of the most common and harmful complications of diabetes, which can negatively impact the health of patients. Western medicine is limited when treating these diseases, and there are obvious side effects associated with some drugs. The tolerance of the middle-aged and elderly is poor. Therefore, more and more experts and scholars have advocated the introduction of Chinese medicine into the treatment of diabetic constipation, of which acupuncture is widely used and its efficacy is well recognized by doctors and patients. This study collated and analyzed the relevant literature reports and studies in the past three years. It was confirmed that the use of acupuncture for diabetic constipation can remarkably improve clinical symptoms, its efficacy and safety are good, and this treatment protocol has positive clinical application value.
糖尿病、高血压和冠心病等慢性疾病由于其加速的老龄化进程而在中国老龄化人口中日益流行,这对人们的健康构成了严重威胁。这些疾病的预防和治疗越来越受到医疗部门的重视。糖尿病是一种代谢性疾病,其特征是多饮、多尿和消瘦,其中2型糖尿病的发病率远高于1型糖尿病。糖尿病有多种并发症,可在疾病进展后发生。糖尿病便秘是糖尿病最常见、最有害的并发症之一,会对患者的健康产生负面影响。西医在治疗这些疾病时是有限的,而且一些药物有明显的副作用。中老年人的承受能力较差。因此,越来越多的专家学者主张将中医药引入糖尿病便秘的治疗中,其中针灸应用广泛,其疗效得到了医生和患者的认可。本研究对近三年来的相关文献报道和研究进行了整理和分析。经证实,针刺治疗糖尿病便秘能显著改善临床症状,疗效和安全性良好,该治疗方案具有积极的临床应用价值。
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引用次数: 0
Clinical Study of Liposuction Combined with Subareolar Incision Adenectomy for Gynecomastia 吸脂术联合乳沟下切口全切除治疗妇科肿瘤的临床研究
Pub Date : 2023-06-09 DOI: 10.26689/jcnr.v7i4.4989
Lu Sun, W. Shao, Xiao-Qi Weng
Objective: To investigate the clinical effect of liposuction combined with subareolar incision glandectomy in the treatment of Simon Grade Ⅲ adipo-glandular gynecomastia (GYN). Methods: From March 2021 to March 2022, the data of patients with Simon Grade Ⅲ adipo-glandular GYN treated by liposuction combined with glandectomy in the Department of Plastic Surgery, Zhongshan Hospital Affiliated to Dalian University and Henan Plastic Surgery and Aesthetic Hospital were retrospectively analyzed. Based on the medical records, color ultrasound was performed on the patient’s breast before surgery, which was determined to be GYN (more than 50% glandular tissue). A 3 mm long incision was made at the lower boundary of the surgical range, through which the adipose tissue in the hypertrophic region of the breast was repeatedly aspirated until a satisfactory thickness was achieved. The residual glandular tissue was removed by a semicircular arc incision under the areola, and then the areola incision was sutured in position. The blood flow, sensation, and wound healing of bilateral nipples and areola were observed after surgery, and the morphology of bilateral thorax and scar of incision were followed up. Results: A total of 15 GYN patients aged 18 to 35 years with body mass index of 23.8 to 26.5 kg/m2 (mean = 24.8 kg/m2) were included in this study. The average intraoperative liposuction volume of unilateral breast was 170 mL (150–200 mL), the average glandectomy volume was 115 g (95–125 g), and the average blood loss was about 40 mL (15–75 mL). Postoperative hypertrophic breast volume decreased significantly, and no complications such as hematoma, infection, skin ischemic necrosis, or sensory disturbance occurred in the nipple and areola, during the healing process. The patients were followed up for 3 to 6 months, and the bilateral thorax was smooth, symmetrical, and natural in contour. The incision was concealed, and the scar was not obvious. Conclusion: Liposuction combined with subareolar incision glandectomy in the treatment of Simon Grade Ⅲ adipo-glandular GYN is safe. The postoperative chest contour is smooth and natural, and the scar is small and invisible, which achieves good aesthetics.
目的:探讨抽脂联合乳腺切除术治疗西蒙Ⅲ级脂肪腺性男性乳房发育症的临床疗效。方法:回顾性分析2021年3月至2022年3月大连大学附属中山医院整形外科、河南省整形美容医院西蒙Ⅲ级脂肪腺妇科抽脂联合腺切除术的患者资料。根据病历,手术前对患者的乳房进行了彩色超声检查,确定为妇科检查(超过50%的腺体组织)。在手术范围的下边界处做了一个3毫米长的切口,通过该切口反复抽吸乳房肥大区域的脂肪组织,直到达到令人满意的厚度。乳晕下半圆形弧形切口切除残留的腺体组织,然后将乳晕切口缝合到位。术后观察双侧乳头和乳晕的血流、感觉和伤口愈合情况,并随访双侧胸部形态和切口瘢痕。结果:本研究共纳入15名年龄在18至35岁之间的妇科患者,其体重指数为23.8至26.5kg/m2(平均值=24.8 kg/m2)。单侧乳房的平均术中吸脂量为170 mL(150–200 mL),平均腺体切除量为115 g(95–125 g),平均失血量约为40 mL(15–75 mL)。术后肥大的乳房体积明显减少,在愈合过程中,乳头和乳晕没有出现血肿、感染、皮肤缺血性坏死或感觉障碍等并发症。患者随访3~6个月,双侧胸部光滑、对称、轮廓自然。切口隐蔽,疤痕不明显。结论:吸脂联合乳腺切除术治疗SimonⅢ级脂肪腺妇科是安全的。术后胸部轮廓光滑自然,疤痕小且不可见,达到了良好的美观效果。
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引用次数: 0
期刊
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