Pub Date : 2009-08-15DOI: 10.1111/J.1699-0463.1981.TB00214.X
N. Graem, A. Fischer, N. Hastrup, C. Povlsen
In a follow-up study of a consecutive series of 1000 patients, who underwent Billroth II resection for duodenal ulcer 22-30 years earlier, the mucosal changes of the gastric stump could be studied by endoscopy and biopsy in 196 cases. At the histological examination only 7.1% of the patients had a normal gastric mucosa: the remaining 92.9% had chronic atrophic gastritis., which was diffuse and most marked at the gastro-jejunostomy. In 7.1% of the cases the inflammation was accompanied by focal accumulation of lipophages. 12.2% had non-neoplastic polyp formation caused either by cystic glandular dilatation of the mucosa at the gastro-jejunostomy, eosinophilic granulomatous polyps or protrusion of the mucosa at the lesser curvature caused by invagination at the resection. 14.8% of the patients had epithelial atypia close to the anastomosis, but no cancers were found, and it is concluded that the presented results do not indicate a cancer prophylactic endoscopic screening of patients treated with Billroth II resection for duodenal ulcer.
{"title":"Mucosal changes of the Billroth II resected stomach. A follow-up study of patients resected for duodenal ulcer,with special reference to gastritis, atypia and cancer.","authors":"N. Graem, A. Fischer, N. Hastrup, C. Povlsen","doi":"10.1111/J.1699-0463.1981.TB00214.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1981.TB00214.X","url":null,"abstract":"In a follow-up study of a consecutive series of 1000 patients, who underwent Billroth II resection for duodenal ulcer 22-30 years earlier, the mucosal changes of the gastric stump could be studied by endoscopy and biopsy in 196 cases. At the histological examination only 7.1% of the patients had a normal gastric mucosa: the remaining 92.9% had chronic atrophic gastritis., which was diffuse and most marked at the gastro-jejunostomy. In 7.1% of the cases the inflammation was accompanied by focal accumulation of lipophages. 12.2% had non-neoplastic polyp formation caused either by cystic glandular dilatation of the mucosa at the gastro-jejunostomy, eosinophilic granulomatous polyps or protrusion of the mucosa at the lesser curvature caused by invagination at the resection. 14.8% of the patients had epithelial atypia close to the anastomosis, but no cancers were found, and it is concluded that the presented results do not indicate a cancer prophylactic endoscopic screening of patients treated with Billroth II resection for duodenal ulcer.","PeriodicalId":6953,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section A, Pathology","volume":"36 1","pages":"227-34"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88033804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-08-15DOI: 10.1111/J.1699-0463.1976.TB00111.X
T. Jørgensen
Numerous papers have emphasized the damaging effect of salicylic acid compounds on the stomach mucosa. The investigations here reported aimed at examining the effect on gastric and duodenal morphology of a moderate dose of aspirin. Oxidative enzymes were evaluated histochemically. To rats in groups of 16, aspirin tablets, placebo tablets, or the same with additional 1 cc of 0.1 N HCl, were administered twice a day for 6 weeks. Approximately 160 mg/kg/24 hrs. were ingested. Microscopy revealed severe hyperaemia along with focal gastritis in the aspirin treated animals. Chronic gactric ulcers were observed in 18 rats in the aspirin treated groups, particularly in the group where HCl was added. Ulcerations in the area of the pyloricgland occurred in the latter group only. A reduction in mucopolysaccharides was demonstrated and involved the acid as well as the neutral ones. NADH-reductase and cytochrome oxidase were inhibited not only in the surface cells but also in those in the deeper layers. The reduction in oxidative enzymes in otherwise undamaged areas suggests an interference with the cellular metabolism, probably processes in the respiratory chain which might lead to reduction in energy-rich phosphate bonds.
{"title":"Ulcer formation and histochemical changes in rat-stomach mucosa induced by acetylsalicylic acid.","authors":"T. Jørgensen","doi":"10.1111/J.1699-0463.1976.TB00111.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1976.TB00111.X","url":null,"abstract":"Numerous papers have emphasized the damaging effect of salicylic acid compounds on the stomach mucosa. The investigations here reported aimed at examining the effect on gastric and duodenal morphology of a moderate dose of aspirin. Oxidative enzymes were evaluated histochemically. To rats in groups of 16, aspirin tablets, placebo tablets, or the same with additional 1 cc of 0.1 N HCl, were administered twice a day for 6 weeks. Approximately 160 mg/kg/24 hrs. were ingested. Microscopy revealed severe hyperaemia along with focal gastritis in the aspirin treated animals. Chronic gactric ulcers were observed in 18 rats in the aspirin treated groups, particularly in the group where HCl was added. Ulcerations in the area of the pyloricgland occurred in the latter group only. A reduction in mucopolysaccharides was demonstrated and involved the acid as well as the neutral ones. NADH-reductase and cytochrome oxidase were inhibited not only in the surface cells but also in those in the deeper layers. The reduction in oxidative enzymes in otherwise undamaged areas suggests an interference with the cellular metabolism, probably processes in the respiratory chain which might lead to reduction in energy-rich phosphate bonds.","PeriodicalId":6953,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section A, Pathology","volume":"1 1","pages":"64-72"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90956196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-08-15DOI: 10.1111/J.1699-0463.1970.TB03309.X
L. Danielsen, H. E. Christensen, J. Wanstrup
{"title":"Cutaneous amyloidosis. Classification, pathogenesis and relation to \"collagen disease\".","authors":"L. Danielsen, H. E. Christensen, J. Wanstrup","doi":"10.1111/J.1699-0463.1970.TB03309.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1970.TB03309.X","url":null,"abstract":"","PeriodicalId":6953,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section A, Pathology","volume":"86 1","pages":"335-344"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79930243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-08-15DOI: 10.1111/J.1699-0463.1976.TB00137.X
P. Krogh, F. Elling, N. Gyrd‐Hansen, B. Hald, A. Larsen, E. Lillehoj, A. Madsen, H. Mortensen, U. Ravnskov
Nine pigs were fed crystalline ochratoxin A in amounts corresponding to a feed level of 1 mg per kg for 3 months. The only observable lesion developed was a kidney damage, identical to the naturally occurring porcine nephropathy. The changes of renal function was characterized by impairment of proximal tubular function, indicated by a decrease of the ratio TmPAH/CIn, of the ability to concentrate urine, and by an increased urinary excretion of glucose. The decrease of the ratio TmPAH/CIn is correlated with time of exposure to ochratoxin A. The changes of renal structure were characterized by degeneration of the proximal tubules, leading to tubular atrophy accompanied by interstitial fibrosis. At the end of the experiment the kidney, liver, adipose and muscular tissue of the slaughtered pigs contained sizable amounts of ochratoxin A residues. As the pigs would have passed the meat inspection this represents a possible health problem. The changes observed in this study are identical to those observed by feeding to pigs grains naturally contaminated with ochratoxin A.
{"title":"Experimental porcine nephropathy: changes of renal function and structure perorally induced by crystalline ochratoxin A.","authors":"P. Krogh, F. Elling, N. Gyrd‐Hansen, B. Hald, A. Larsen, E. Lillehoj, A. Madsen, H. Mortensen, U. Ravnskov","doi":"10.1111/J.1699-0463.1976.TB00137.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1976.TB00137.X","url":null,"abstract":"Nine pigs were fed crystalline ochratoxin A in amounts corresponding to a feed level of 1 mg per kg for 3 months. The only observable lesion developed was a kidney damage, identical to the naturally occurring porcine nephropathy. The changes of renal function was characterized by impairment of proximal tubular function, indicated by a decrease of the ratio TmPAH/CIn, of the ability to concentrate urine, and by an increased urinary excretion of glucose. The decrease of the ratio TmPAH/CIn is correlated with time of exposure to ochratoxin A. The changes of renal structure were characterized by degeneration of the proximal tubules, leading to tubular atrophy accompanied by interstitial fibrosis. At the end of the experiment the kidney, liver, adipose and muscular tissue of the slaughtered pigs contained sizable amounts of ochratoxin A residues. As the pigs would have passed the meat inspection this represents a possible health problem. The changes observed in this study are identical to those observed by feeding to pigs grains naturally contaminated with ochratoxin A.","PeriodicalId":6953,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section A, Pathology","volume":"1173 1","pages":"429-34"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72708755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-08-15DOI: 10.1111/J.1699-0463.1970.TB03308.X
L. Boquist
Changes that were interpreted to be of regenerative nature were studied in Chinese hamsters treated with ethionine or excess methionine. Numerous ductules and associated nodules of rather large cells were seen in the light microscope. Ultrastructurally, the endoplasmic reticulum of unaffected and damaged acinar cells showed a whorled appearance. Exocrine cells with no or few zymogen granules and low or moderate cytoplasmic electron density were found. There were other exocrine cells that exhibited prominent endoplasmic reticulum consisting of vacuoles, vesicles, and cisternae, the latter containing electron dense masses. Occasional mitoses were seen in acinar and ductule cells. The endocrine pancreas showed some new formation of cells, with the occurence of granulated cells in ductules. It is suggested that, in pancreas damaged by the administration of ethionine or excess methionine; there is regeneration of acinar parenchyma by mitotic cell division, by restitution of damaged cells, as well as by new formation of cells from ductules. In addition, there is some new formation of endocrine cells.
{"title":"Regeneration of exo- and endocrine pancreas. Morphological studies of lesions induced by ethionine or excess methionine.","authors":"L. Boquist","doi":"10.1111/J.1699-0463.1970.TB03308.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1970.TB03308.X","url":null,"abstract":"Changes that were interpreted to be of regenerative nature were studied in Chinese hamsters treated with ethionine or excess methionine. Numerous ductules and associated nodules of rather large cells were seen in the light microscope. Ultrastructurally, the endoplasmic reticulum of unaffected and damaged acinar cells showed a whorled appearance. Exocrine cells with no or few zymogen granules and low or moderate cytoplasmic electron density were found. There were other exocrine cells that exhibited prominent endoplasmic reticulum consisting of vacuoles, vesicles, and cisternae, the latter containing electron dense masses. Occasional mitoses were seen in acinar and ductule cells. The endocrine pancreas showed some new formation of cells, with the occurence of granulated cells in ductules. It is suggested that, in pancreas damaged by the administration of ethionine or excess methionine; there is regeneration of acinar parenchyma by mitotic cell division, by restitution of damaged cells, as well as by new formation of cells from ductules. In addition, there is some new formation of endocrine cells.","PeriodicalId":6953,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section A, Pathology","volume":"144 1","pages":"323-34"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73324419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-08-15DOI: 10.1111/J.1699-0463.1974.TB00374.X
O. Closs, O. Haugen
{"title":"Experimental murine leprosy. 2. Further evidence for varying susceptibility of outbred mice and evaluation of the response of 5 inbred mouse strains to infection with Mycobacterium lepraemurium.","authors":"O. Closs, O. Haugen","doi":"10.1111/J.1699-0463.1974.TB00374.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1974.TB00374.X","url":null,"abstract":"","PeriodicalId":6953,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section A, Pathology","volume":"202 1","pages":"459-74"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74886264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-08-15DOI: 10.1111/j.1699-0463.1974.tb00382.x
Johan A. Andersen
During a retrospective histological study based on examination of 3299 female breast tissue specimens with otherwise benign diseases, 52 cases of lobular carcinoma in situ were found. Five cases presented previous invasive breast carcinoma, and one of these developed subsequently invasive carcinoma during the first year after the biopsy. Out of 47 cases without previous invasive breast carcinoma, 10 developed subsequently 12 invasive carcinomas. Eight were ipsilateral and were revealed within the 1st, 2nd, 3rd, 5th, 7th, 14th, 18th, and 22nd year, respectively. Four were contralateral and were found within the 7th, 8th, 12th, and 24th year after the primary biopsy. The average follow-up period was 15 years. Strict follow-up of patients with lobular carcinoma in situ, carried out by a permanent team, is considered a realistic alternative to mastectomy.
{"title":"Lobular carcinoma in situ. A long-term follow-up in 52 cases.","authors":"Johan A. Andersen","doi":"10.1111/j.1699-0463.1974.tb00382.x","DOIUrl":"https://doi.org/10.1111/j.1699-0463.1974.tb00382.x","url":null,"abstract":"During a retrospective histological study based on examination of 3299 female breast tissue specimens with otherwise benign diseases, 52 cases of lobular carcinoma in situ were found. Five cases presented previous invasive breast carcinoma, and one of these developed subsequently invasive carcinoma during the first year after the biopsy. Out of 47 cases without previous invasive breast carcinoma, 10 developed subsequently 12 invasive carcinomas. Eight were ipsilateral and were revealed within the 1st, 2nd, 3rd, 5th, 7th, 14th, 18th, and 22nd year, respectively. Four were contralateral and were found within the 7th, 8th, 12th, and 24th year after the primary biopsy. The average follow-up period was 15 years. Strict follow-up of patients with lobular carcinoma in situ, carried out by a permanent team, is considered a realistic alternative to mastectomy.","PeriodicalId":6953,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section A, Pathology","volume":"232 1","pages":"519-533"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79698615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-08-15DOI: 10.1111/J.1699-0463.1977.TB00453.X
H. Hamberg, U. Brunk, J. Ericsson, B. Jung
{"title":"CYTOPLASMIC EFFECTS OF X-IRRADIATION ON CULTURED CELLS IN A NON-DIVIDING STAGE: 2. Alterations in Lysosomes, Plasma Membrane, Golgi Apparatus, and Related Structures","authors":"H. Hamberg, U. Brunk, J. Ericsson, B. Jung","doi":"10.1111/J.1699-0463.1977.TB00453.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1977.TB00453.X","url":null,"abstract":"","PeriodicalId":6953,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section A, Pathology","volume":"18 1","pages":"625-639"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75732200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-08-15DOI: 10.1111/J.1699-0463.1981.TB00245.X
L. Rode, E. Ophus, B. Gylseth
Autopsy findings in a 55-year old man known to have been occupationally heavily exposed to titanium dioxide dust showed extensive pulmonary deposition of white pigment. By energy dispersive X-ray analysis (EDAX) and electron and X-ray diffraction, the pigment was identified as rutile. By ordinary transmitted light microscopy, deposits of the white crystalline titanium-dioxide could not be distinguished from anthracotic pigment present in the lung sections. By transmitted polarized and incident light microscopy, the different nature of the two types of pigment was immediately evident. Absence of inflammatory and fibrotic changes in the lungs in our case lends support to the view that rutile is biochemically inert.
{"title":"Massive pulmonary deposition of rutile after titanium dioxide exposure: Light-microscopical and physico-analytical methods in pigment identification.","authors":"L. Rode, E. Ophus, B. Gylseth","doi":"10.1111/J.1699-0463.1981.TB00245.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1981.TB00245.X","url":null,"abstract":"Autopsy findings in a 55-year old man known to have been occupationally heavily exposed to titanium dioxide dust showed extensive pulmonary deposition of white pigment. By energy dispersive X-ray analysis (EDAX) and electron and X-ray diffraction, the pigment was identified as rutile. By ordinary transmitted light microscopy, deposits of the white crystalline titanium-dioxide could not be distinguished from anthracotic pigment present in the lung sections. By transmitted polarized and incident light microscopy, the different nature of the two types of pigment was immediately evident. Absence of inflammatory and fibrotic changes in the lungs in our case lends support to the view that rutile is biochemically inert.","PeriodicalId":6953,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section A, Pathology","volume":"8 1","pages":"455-61"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74917557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-08-15DOI: 10.1111/J.1699-0463.1977.TB03884.X
P. Stubbe Teglbjaerg, M. Vetner
One-hundred and fifteen gastric adenocarcinomas were classified according to Mulligan and Rember into one of the following types: Intestinal cell carcinoma (IC), pyloro-cardiac gland carcinoma (PC), mucous cell carcinoma (MC) and unclassified. The tumour type was correlated to the growth pattern and inflammatory reaction at the margin of the tumour, invasion of the veins and nerve sheaths, Dukes' stage, intra- and extracellular mucous production, and occurrence of intestinal metaplasia in the non-tumour bearing parts of the gastric mucosa. MC was the only type of tumour producing the macroscopic picture "linitis plastica". PC was the type of tumour that dominated in the cardiac region. The following parameters showed no relation to tumour type: Sex and age, size of tumour, invasion of lymphatic vessels. This study suggests that the three types of tumour are different entities, MC being the most aggressive and IC the least aggressive of the types of tumour.
{"title":"Gastric carcinoma 2. An analysis of morphological and prognostic parameters correlated to the classification proposed by Masson, Rember and Mulligan.","authors":"P. Stubbe Teglbjaerg, M. Vetner","doi":"10.1111/J.1699-0463.1977.TB03884.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1977.TB03884.X","url":null,"abstract":"One-hundred and fifteen gastric adenocarcinomas were classified according to Mulligan and Rember into one of the following types: Intestinal cell carcinoma (IC), pyloro-cardiac gland carcinoma (PC), mucous cell carcinoma (MC) and unclassified. The tumour type was correlated to the growth pattern and inflammatory reaction at the margin of the tumour, invasion of the veins and nerve sheaths, Dukes' stage, intra- and extracellular mucous production, and occurrence of intestinal metaplasia in the non-tumour bearing parts of the gastric mucosa. MC was the only type of tumour producing the macroscopic picture \"linitis plastica\". PC was the type of tumour that dominated in the cardiac region. The following parameters showed no relation to tumour type: Sex and age, size of tumour, invasion of lymphatic vessels. This study suggests that the three types of tumour are different entities, MC being the most aggressive and IC the least aggressive of the types of tumour.","PeriodicalId":6953,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section A, Pathology","volume":"33 1","pages":"528-34"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86600001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：