Pub Date : 2009-08-15DOI: 10.1111/J.1699-0463.1971.TB00517.X
O. Grüner
At autopsy, Actinomyces colonies were found in the tonsils in 9 out of 22 bodies under the age of 35 years. This seems to indicate that tonsillar crypts is a normal habitat of such colonies.
{"title":"Actinomyces in tonsillar tissue. A histological study of an autopsy material.","authors":"O. Grüner","doi":"10.1111/J.1699-0463.1971.TB00517.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1971.TB00517.X","url":null,"abstract":"At autopsy, Actinomyces colonies were found in the tonsils in 9 out of 22 bodies under the age of 35 years. This seems to indicate that tonsillar crypts is a normal habitat of such colonies.","PeriodicalId":6953,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section A, Pathology","volume":"78 1","pages":"77-8"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85504679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-08-15DOI: 10.1111/J.1699-0463.1977.TB00458.X
A. Bylock, S. Björkerud, R. Brattsand, G. Hansson, H. Hansson, G. Bondjers
: The aortic surface of rabbits given a supplement of 0.1--0.3 per cent cholesterol to the diet was studied by scanning electron microscopy. In regions where increased haemodynamic strain was anticipated, similar structural changes were observed in normal and hypercholesterolaemic rabbits. However, changes indicating cell injury were more wide-spread in cholesterolfed animals. This suggests that hypercholesterolaemia may increase cell susceptibility to injury. In the same regions, the development of intimal thickenings was observed in cholesterol-fed rabbits. The central parts of such thickenings had been reendothlialized, whereas a region with cell injury surrounded each lesion. In regions with low haemodynamic strain, a loss of fine-structural details was observed in hypercholesterolaemic rabbits. It is suggested that these changes may be related to the deteriorated functional properties of the intact endothelium in such rabbits. In view of these data it is suggested that the interrelationship between hypercholesterolaemia and atherosclerotic arterial disease may partly be due to a deleterious effect of hypercholesterolaemia on the functional and structural integrity of the arterial endothelium.
{"title":"ENDOTHELIAL STRUCTURE IN RABBITS WITH MODERATE HYPERCHOLESTEROLAEMI","authors":"A. Bylock, S. Björkerud, R. Brattsand, G. Hansson, H. Hansson, G. Bondjers","doi":"10.1111/J.1699-0463.1977.TB00458.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1977.TB00458.X","url":null,"abstract":": The aortic surface of rabbits given a supplement of 0.1--0.3 per cent cholesterol to the diet was studied by scanning electron microscopy. In regions where increased haemodynamic strain was anticipated, similar structural changes were observed in normal and hypercholesterolaemic rabbits. However, changes indicating cell injury were more wide-spread in cholesterolfed animals. This suggests that hypercholesterolaemia may increase cell susceptibility to injury. In the same regions, the development of intimal thickenings was observed in cholesterol-fed rabbits. The central parts of such thickenings had been reendothlialized, whereas a region with cell injury surrounded each lesion. In regions with low haemodynamic strain, a loss of fine-structural details was observed in hypercholesterolaemic rabbits. It is suggested that these changes may be related to the deteriorated functional properties of the intact endothelium in such rabbits. In view of these data it is suggested that the interrelationship between hypercholesterolaemia and atherosclerotic arterial disease may partly be due to a deleterious effect of hypercholesterolaemia on the functional and structural integrity of the arterial endothelium.","PeriodicalId":6953,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section A, Pathology","volume":"1937 1","pages":"671-682"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91171823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-08-15DOI: 10.1111/J.1699-0463.1976.TB00109.X
T. Berge, A. Brun, B. Hansing, B. Kjellman
: Generalized lipodystrophy (Berardinelli-Seip's syndrome) was diagnosied in a boy at the age of 8-1/2 months. Ten months later he died because of aspiration of food. Necropsy with special reference to the CNS revealed hypothalamic lesions, probably of a malformative or hamartomatous nature. The findings lend additional support to the view that hypothalamic dysfunction is responsible for the signs and symptoms of generalized lipodystrophy.
{"title":"Congenital generalized lipodystrophy. Report on one case, with special reference to postmortem findings.","authors":"T. Berge, A. Brun, B. Hansing, B. Kjellman","doi":"10.1111/J.1699-0463.1976.TB00109.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1976.TB00109.X","url":null,"abstract":": Generalized lipodystrophy (Berardinelli-Seip's syndrome) was diagnosied in a boy at the age of 8-1/2 months. Ten months later he died because of aspiration of food. Necropsy with special reference to the CNS revealed hypothalamic lesions, probably of a malformative or hamartomatous nature. The findings lend additional support to the view that hypothalamic dysfunction is responsible for the signs and symptoms of generalized lipodystrophy.","PeriodicalId":6953,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section A, Pathology","volume":"16 1","pages":"47-54"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81273373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-08-15DOI: 10.1111/J.1699-0463.1974.TB00370.X
R. Lemperg, J. Rosenquist
{"title":"Effects of supply and withdrawal of fluoride. Experimental studies on growing and adult rabbits. 3. Concentration of acid glycosaminoglycans and hydroxyproline in cortical bone.","authors":"R. Lemperg, J. Rosenquist","doi":"10.1111/J.1699-0463.1974.TB00370.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1974.TB00370.X","url":null,"abstract":"","PeriodicalId":6953,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section A, Pathology","volume":"53 1","pages":"435-44"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78137368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-08-15DOI: 10.1111/J.1699-0463.1977.TB03883.X
P. Stubbe Teglbjaerg, M. Vetner
The purpose of the present paper has been to examine the reproducibility of the classification of gastric carcinomas, as proposed by Mulligan and Rember. Two microscopic slides from each of one hundred randomly selected specimens of gastric carcinoma, obtained by gastrectomy or gastric resection, were classified independently by both authors. Neither of the authors knew which slides originated from the same specimen. The inter-examiner reproducibility rate was 79 per cent. The reproducibility rates of the diagnoses with two independent slides from the same tumour was 74 per cent with examiner I and 80 per cent with examiner II.
{"title":"Gastric carcinoma I. The reproducibility of a histogenetic classification proposed by Masson, Rember and Mulligan.","authors":"P. Stubbe Teglbjaerg, M. Vetner","doi":"10.1111/J.1699-0463.1977.TB03883.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1977.TB03883.X","url":null,"abstract":"The purpose of the present paper has been to examine the reproducibility of the classification of gastric carcinomas, as proposed by Mulligan and Rember. Two microscopic slides from each of one hundred randomly selected specimens of gastric carcinoma, obtained by gastrectomy or gastric resection, were classified independently by both authors. Neither of the authors knew which slides originated from the same specimen. The inter-examiner reproducibility rate was 79 per cent. The reproducibility rates of the diagnoses with two independent slides from the same tumour was 74 per cent with examiner I and 80 per cent with examiner II.","PeriodicalId":6953,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section A, Pathology","volume":"73 1","pages":"519-27"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83972446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-08-15DOI: 10.1111/J.1699-0463.1970.TB02536.X
Finn Lindahl
The development of a malignant tumour in a stillborn infant is reported. The tumour was localized to the maxilla and metastases to lymph nodes, liver, and adrenal glands were in evidence. By microscopy of the primary tumour the latter was found to be characterized by a sporadic occurrence of pigment; in addition, metastases to the adrenal glands were found to comprise fontana-positive cells. If these features be related to the localization of the tumour and the age of the patient it seems natural to suggest that it is a matter of a melanotic progonoma although this type of tumour previously has been considered a benign growth.
{"title":"MALIGNANT MELANOTIC PROGONOM","authors":"Finn Lindahl","doi":"10.1111/J.1699-0463.1970.TB02536.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1970.TB02536.X","url":null,"abstract":"The development of a malignant tumour in a stillborn infant is reported. The tumour was localized to the maxilla and metastases to lymph nodes, liver, and adrenal glands were in evidence. By microscopy of the primary tumour the latter was found to be characterized by a sporadic occurrence of pigment; in addition, metastases to the adrenal glands were found to comprise fontana-positive cells. If these features be related to the localization of the tumour and the age of the patient it seems natural to suggest that it is a matter of a melanotic progonoma although this type of tumour previously has been considered a benign growth.","PeriodicalId":6953,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section A, Pathology","volume":"1 1","pages":"532-536"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83624252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-08-15DOI: 10.1111/J.1699-0463.1974.TB00378.X
J. Rosenquist, R. Lemperg
{"title":"Effects of supply and withdrawal of fluoride. Experimental studies on growing and adult rabbits. 7. Long-term observations on the reversibility of skeletal fluorosis.","authors":"J. Rosenquist, R. Lemperg","doi":"10.1111/J.1699-0463.1974.TB00378.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1974.TB00378.X","url":null,"abstract":"","PeriodicalId":6953,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section A, Pathology","volume":"32 1","pages":"495-8"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73353203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-08-15DOI: 10.1111/j.1699-0463.1977.tb00436.x
Sørensen Fh
A quantitative study including total and differential counts of nuclei and determination of mesangial and total glomerular area was carried out on kidney tissue from 21 persons without renal disease, in order to determine the normal values of glomerular parameters and to estimate the possible influence of age and physiological degrees of arteriolosclerosis. No age dependency was found to exist for the glomerular parameters within the age category of 17 to 45 years. Above the age of forty-five a rise in mesangial area per cent of total area and mesangial nuclei per cent of total nuclei was found on increasing age, while a decline on increasing age was demonstrated for epithelial nuclei per cent of total nuclei. The mean value of mesangial nuclei per 1000 micron2 of mesangial area was found to be significantly higher in the older age category than in the younger. Arteriolosclerosis did not appear to influence the parameters. The study also attempted to describe the three variance components: interrenal, interfocal and interglomerular variation. Interfocal variation was the smallest part of the total variation, and interrenal plus interfocal variation was at most of the same size os interglomerular variation.
{"title":"Quantitative studies of the renal corpuscles IV. Determination of normal values in various age categories, and an analysis of the possible influence of physiological degrees of arteriolosclerosis.","authors":"Sørensen Fh","doi":"10.1111/j.1699-0463.1977.tb00436.x","DOIUrl":"https://doi.org/10.1111/j.1699-0463.1977.tb00436.x","url":null,"abstract":"A quantitative study including total and differential counts of nuclei and determination of mesangial and total glomerular area was carried out on kidney tissue from 21 persons without renal disease, in order to determine the normal values of glomerular parameters and to estimate the possible influence of age and physiological degrees of arteriolosclerosis. No age dependency was found to exist for the glomerular parameters within the age category of 17 to 45 years. Above the age of forty-five a rise in mesangial area per cent of total area and mesangial nuclei per cent of total nuclei was found on increasing age, while a decline on increasing age was demonstrated for epithelial nuclei per cent of total nuclei. The mean value of mesangial nuclei per 1000 micron2 of mesangial area was found to be significantly higher in the older age category than in the younger. Arteriolosclerosis did not appear to influence the parameters. The study also attempted to describe the three variance components: interrenal, interfocal and interglomerular variation. Interfocal variation was the smallest part of the total variation, and interrenal plus interfocal variation was at most of the same size os interglomerular variation.","PeriodicalId":6953,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section A, Pathology","volume":"19 1","pages":"356-366"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74522034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-08-15DOI: 10.1111/J.1699-0463.1976.TB00139.X
E. S. Hansen, P. Tauris
A case is reported of methicillin-induced acute interstitial lymphocytic nephritis following treatment of a Staphylococcus aureus infection. Direct immunofluorescence showed a linear staining of the tubular basement membrane with anti-IgG and -C3. It is suggested that both cellular and humoral immunologic mechanisms are of pathogenic importance.
{"title":"Methicillin-induced nephropathy. A case with linear deposition of IgG and C3 on the tubular-basement-membrane.","authors":"E. S. Hansen, P. Tauris","doi":"10.1111/J.1699-0463.1976.TB00139.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1976.TB00139.X","url":null,"abstract":"A case is reported of methicillin-induced acute interstitial lymphocytic nephritis following treatment of a Staphylococcus aureus infection. Direct immunofluorescence showed a linear staining of the tubular basement membrane with anti-IgG and -C3. It is suggested that both cellular and humoral immunologic mechanisms are of pathogenic importance.","PeriodicalId":6953,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section A, Pathology","volume":"37 1","pages":"440-2"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74750765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-08-15DOI: 10.1111/J.1699-0463.1976.TB00104.X
C. O. Polvsen
In 32 experiments involving transplantation of human malignant melanomas to the mouse mutant nude, tumourtake was observed in 14 instances. The tumour tissue which took and grew after inoculation was derived from malignant melanoma metastases of the skin (10 takes from 13 transplantations), and from primary malignant melanomas of the eye (4 takes from 6 transplantations). Not one of 13 attempts to transplant primary tumours of the skin was successful. In 7 instances serial transfers of transplanted tumour were successful, the degree of success ranging from 3 to 41 passages. Some passages were wilfully interrupted but two are continuing. The transplanted tumours grow locally. Neither lymph node metastases nor organ metastases have been observed. Histological appearances of the transplanted tumours, also after serial passages, were identical with those of the original human donor material. The human tumour/nude mouse system is contrasted and compared with other heterotransplantation models.
{"title":"Heterotransplantation of human malignant melanomas to the mouse mutant nude.","authors":"C. O. Polvsen","doi":"10.1111/J.1699-0463.1976.TB00104.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1976.TB00104.X","url":null,"abstract":"In 32 experiments involving transplantation of human malignant melanomas to the mouse mutant nude, tumourtake was observed in 14 instances. The tumour tissue which took and grew after inoculation was derived from malignant melanoma metastases of the skin (10 takes from 13 transplantations), and from primary malignant melanomas of the eye (4 takes from 6 transplantations). Not one of 13 attempts to transplant primary tumours of the skin was successful. In 7 instances serial transfers of transplanted tumour were successful, the degree of success ranging from 3 to 41 passages. Some passages were wilfully interrupted but two are continuing. The transplanted tumours grow locally. Neither lymph node metastases nor organ metastases have been observed. Histological appearances of the transplanted tumours, also after serial passages, were identical with those of the original human donor material. The human tumour/nude mouse system is contrasted and compared with other heterotransplantation models.","PeriodicalId":6953,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section A, Pathology","volume":"113 1","pages":"9-16"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80823074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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